Development Level

Tbio 47 | 11,445
Tchem 8 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 5 | 278
abnormal behavior 3 | 298
decreased body weight 3 | 161
increased blood urea nitrogen ... 3 | 48
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal embryo turning 2 | 31
abnormal forebrain development 2 | 20
abnormal gait 2 | 69
abnormal hindbrain development 2 | 16
abnormal limb bud morphology 2 | 17
abnormal midbrain development 2 | 20
abnormal neural tube closure 2 | 46
abnormal pericardium morpholog... 2 | 26
decreased lean body mass 2 | 135
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
pale yolk sac 2 | 25
pallor 2 | 34
thrombocytopenia 2 | 56
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal left-right axis patte... 1 | 2
abnormal limb morphology 1 | 13
abnormal liver size 1 | 5
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal somite shape 1 | 5
abnormal stomach morphology 1 | 10
abnormal tail bud morphology 1 | 8
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
abnormal whole-body plethysmog... 1 | 4
curly tail 1 | 1
cyanosis 1 | 7
decreased B cell number 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
kinked tail 1 | 2
mammalian phenotype 1 | 17
pale liver 1 | 6
respiratory system phenotype 1 | 2
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 43 | 11,493
osteosarcoma 32 | 7,950
ovarian cancer 28 | 8,520
ependymoma 23 | 4,679
glioblastoma 22 | 5,792
Cancer 21 | 2,499
psoriasis 20 | 6,694
medulloblastoma, large-cell 19 | 6,241
atypical teratoid / rhabdoid tumor 17 | 5,112
malignant mesothelioma 17 | 3,232
lung cancer 16 | 4,740
Breast cancer 15 | 3,578
Polydactyly 15 | 107
group 3 medulloblastoma 15 | 4,104
invasive ductal carcinoma 15 | 2,951
Autosomal recessive predisposition 14 | 1,442
lung adenocarcinoma 14 | 2,716
non-small cell lung cancer 14 | 2,890
Intellectual disability 13 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Congenital heart disease 12 | 93
lung carcinoma 12 | 2,843
pancreatic cancer 12 | 2,398
Astrocytoma, Pilocytic 11 | 3,081
Brachydactyly 11 | 156
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Short stature 11 | 531
adult high grade glioma 11 | 3,801
astrocytic glioma 11 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
breast carcinoma 10 | 1,638
interstitial cystitis 10 | 2,312
Cognitive delay 9 | 608
Congenital hypoplasia of penis 9 | 176
Global developmental delay 9 | 608
Kidney cancer 9 | 2,613
Mental and motor retardation 9 | 608
diabetes mellitus 9 | 1,728
primitive neuroectodermal tumor 9 | 3,035
Ciliopathy 8 | 71
Hypertensive disease 8 | 292
Pick disease 8 | 1,894
Seizures 8 | 596
Situs Inversus 8 | 65
chronic rhinosinusitis 8 | 512
ductal carcinoma in situ 8 | 1,745
oligodendroglioma 8 | 2,850
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
Cleft Palate 7 | 271
Epilepsy 7 | 792
Gastrointestinal Stromal Tumors 7 | 48
Increase in blood pressure 7 | 119
Obesity 7 | 678
Orbital separation excessive 7 | 244
Broad flat nasal bridge 6 | 236
Cardiomegaly 6 | 116
Craniofacial Abnormalities 6 | 151
Cryptorchidism 6 | 296
Hypogonadism 6 | 173
Nasal bridge wide 6 | 236
Osteoporosis 6 | 363
Retinitis Pigmentosa 6 | 226
Right atrial isomerism 6 | 29
Ulnar polydactyly of fingers 6 | 47
Vascular disease 6 | 319
dermatomyositis 6 | 966
medulloblastoma 6 | 720
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,109
Anteverted nostril 5 | 191
Congenital hypoplasia of ovary 5 | 30
Electroretinogram abnormal 5 | 95
Heart disease 5 | 306
Hydrocephalus 5 | 152
Hypoplastic ovary 5 | 30
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Language Delay 5 | 112
Lobar Holoprosencephaly 5 | 20
Nystagmus 5 | 317
Small head 5 | 374
Strabismus 5 | 270
Syndactyly 5 | 88
Ventricular Septal Defects 5 | 119
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
cystic fibrosis 5 | 1,696
gastric cancer 5 | 459
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819

Tissue

Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Skin and soft tissues 54 | 17,230
Digestive Tract 52 | 17,369
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Respiratory system 52 | 16,393
Nervous System 51 | 16,725
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 29 | 12,091
Transcription Factor 20 | 1,400
Enzyme 4 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Process

heart looping 57 | 57
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Transcription factor Ovo-like 2 OVOL2 Tbio Transcription Factor -1.20117 17.4 110
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Mesoderm posterior protein 1 MESP1 Tbio Transcription Factor -1.38536 26.8 208
Homeobox protein notochord NOTO Tdark Transcription Factor -2.36366 209.2 26
[F-actin]-monooxygenase MICAL2 MICAL2 Tbio Enzyme -0.47649 3.62 57