Development Level

Tbio 16 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
increased total body fat amoun... 3 | 134
abnormal retina morphology 2 | 71
decreased lean body mass 2 | 135
impaired pupillary reflex 2 | 26
increased startle reflex 2 | 112
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating serum al... 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
fused cornea and lens 1 | 5
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
iris synechia 1 | 3
limb grasping 1 | 41
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 20 | 11,493
psoriasis 15 | 6,694
Cancer 14 | 2,499
glioblastoma 14 | 5,792
ovarian cancer 13 | 8,520
Breast cancer 11 | 3,578
ependymoma 11 | 4,679
Astrocytoma, Pilocytic 10 | 3,081
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 10 | 4,740
medulloblastoma, large-cell 10 | 6,241
interstitial cystitis 9 | 2,312
non-small cell lung cancer 9 | 2,890
osteosarcoma 9 | 7,950
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
Cleft Palate 7 | 271
Intellectual disability 7 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
Cleft Lip 6 | 141
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
spina bifida 6 | 1,074
Alzheimer's disease 5 | 658
Craniofacial Abnormalities 5 | 151
Kidney cancer 5 | 2,613
Skin cancer 5 | 469
Syndactyly of fingers 5 | 48
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
Atopic dermatitis 4 | 952
Cell Transformation, Neoplastic 4 | 97
Choanal Atresia 4 | 42
Colonic Neoplasms 4 | 142
Dental caries 4 | 164
Hydronephrosis 4 | 89
Hypodontia 4 | 81
Hypotrichosis 4 | 47
Liver Cirrhosis 4 | 181
Lymphoid leukemia 4 | 160
Neoplastic Cell Transformation 4 | 89
Palmoplantar keratosis 4 | 74
Rotting teeth 4 | 73
Schizophrenia 4 | 1,160
Short stature 4 | 531
Skin Abnormalities 4 | 37
Strabismus 4 | 270
Syndactyly 4 | 88
Syndactyly of the toes 4 | 45
Wooly hair 4 | 17
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
nephrosclerosis 4 | 333
Adenoma 3 | 167
Bilateral fifth finger clinodactyly 3 | 110
Byzanthine arch palate 3 | 194
Craniosynostosis 3 | 74
Curvature of little finger 3 | 110
Epilepsy 3 | 792
Hernia, Inguinal 3 | 89
High forehead 3 | 102
Liver cancer 3 | 604
Long philtrum 3 | 137
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Melanoma 3 | 711
Mesothelioma, Malignant 3 | 105
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
Skin hyperelastic 3 | 32
Sparse hair 3 | 59
Stomach Neoplasms 3 | 300
Thin, sparse hair 3 | 59
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010

Tissue

Female tissues 25 | 17,400
Endocrine System 24 | 18,159
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Liver and Pancreas 23 | 16,750
Digestive Tract 22 | 17,369
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Blood and immune system 21 | 16,909
Urinary Tract 21 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 17 | 12,091
Transcription Factor 4 | 1,400
Enzyme 3 | 4,145
GPCR 1 | 408
Kinase 1 | 634

GO Process

hair follicle morphogenesis 26 | 26
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Insulin-like growth factor-binding protein 5 IGFBP5 Tchem Non-IDG -2.52721 351.8 278
Sclerostin domain-containing protein 1 SOSTDC1 Tbio Non-IDG -2.29355 177.8 109
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Protein Wnt-10a WNT10A Tbio Non-IDG -2.66153 436.3 118
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Keratin, type I cytoskeletal 27 KRT27 Tdark Non-IDG 0.04 0.92 11
Keratin, type I cytoskeletal 25 KRT25 Tbio Non-IDG -0.59195 2.65 85
Keratin, type II cytoskeletal 71 KRT71 Tbio Non-IDG -0.88301 7.82 64
Forkhead box protein E1 FOXE1 Tbio Transcription Factor -2.41790 254.9 187