Development Level

Tbio 31 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

enlarged heart 3 | 210
preweaning lethality, incomple... 3 | 499
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal head morphology 2 | 10
abnormal seminal vesicle morph... 2 | 114
abnormal snout morphology 2 | 23
decreased circulating HDL chol... 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
hydrometra 2 | 53
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
abnormal autopod morphology 1 | 1
abnormal coat- hair morphology 1 | 19
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal motor capabilities-co... 1 | 5
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal skin morphology 1 | 50
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal stomach morphology 1 | 10
abnormal tail length 1 | 3
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal thymus morphology 1 | 7
abnormal tibia morphology 1 | 14
absent vibrissae 1 | 12
athymia 1 | 2
brachydactyly 1 | 19
cataract 1 | 92
curly tail 1 | 1
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
fusion of vertebral arches 1 | 7
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
kinked tail 1 | 2
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 27 | 11,493
ovarian cancer 21 | 8,520
psoriasis 20 | 6,694
glioblastoma 17 | 5,792
osteosarcoma 17 | 7,950
Breast cancer 16 | 3,578
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 13 | 4,679
lung cancer 13 | 4,740
Kidney cancer 12 | 2,613
adult high grade glioma 12 | 3,801
interstitial cystitis 12 | 2,312
malignant mesothelioma 12 | 3,232
medulloblastoma, large-cell 12 | 6,241
Astrocytoma, Pilocytic 10 | 3,081
group 3 medulloblastoma 10 | 4,104
Cancer 9 | 2,499
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
oligodendroglioma 9 | 2,850
pancreatic cancer 9 | 2,398
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
Autosomal recessive predisposition 7 | 1,442
Hypotrichosis 6 | 47
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
Breast Neoplasms 5 | 445
Mammary Neoplasms 5 | 425
Pick disease 5 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Acquired scoliosis 4 | 281
Alopecia 4 | 115
Craniofacial Abnormalities 4 | 151
Curvature of spine 4 | 282
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Schizophrenia 4 | 1,160
cutaneous lupus erythematosus 4 | 1,057
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Adenoma 3 | 167
Anencephaly 3 | 26
Animal Mammary Neoplasms 3 | 136
Big calvaria 3 | 147
Byzanthine arch palate 3 | 194
Colonic Neoplasms 3 | 142
Colorectal Neoplasms 3 | 243
Concave bridge of nose 3 | 195
Congenital Epicanthus 3 | 177
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Hypertensive disease 3 | 292
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Lung Neoplasms 3 | 232
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Melanoma 3 | 711
Monilethrix 3 | 18
Neural Tube Defects, Susceptibility to 3 | 8
Orbital separation excessive 3 | 244
Sparse eyebrow 3 | 42
Tooth Abnormalities 3 | 69
active Crohn's disease 3 | 922
atypical teratoid/rhabdoid tumor 3 | 357
esophageal adenocarcinoma 3 | 737
head and neck cancer 3 | 271
tuberculosis 3 | 2,010
Adenocarcinoma of lung 2 | 142
Blepharoptosis 2 | 231
Exophthalmos 2 | 112
Frontal bossing 2 | 157
Joint hyperflexibility 2 | 78
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Mesothelioma, Malignant 2 | 105
Neoplasm Invasiveness 2 | 161
Pediatric failure to thrive 2 | 365
Skin cancer 2 | 469
Unipolar Depression 2 | 250
posterior fossa group A ependymoma 2 | 468

Tissue

Skin and soft tissues 37 | 17,230
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Digestive Tract 35 | 17,369
Blood and immune system 34 | 16,909
Male tissues 34 | 17,142
Urinary Tract 34 | 16,678
Nervous System 33 | 16,725
Liver and Pancreas 32 | 16,750
Respiratory system 32 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 19 | 12,091
Transcription Factor 8 | 1,400
GPCR 5 | 408
Enzyme 3 | 4,145
Kinase 2 | 634

GO Process

hair follicle development 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor SOX-21 SOX21 Tbio Transcription Factor -1.47198 29.1 106
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Palmitoyltransferase ZDHHC21 ZDHHC21 Tbio Enzyme -0.65091 4.34 94
LIM/homeobox protein Lhx2 LHX2 Tbio Transcription Factor -1.93103 91.8 221
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Homeobox protein aristaless-like 4 ALX4 Tbio Transcription Factor -1.77762 62.7 213
LIM domain-binding protein 2 LDB2 Tbio Non-IDG -1.58628 38.6 191
Forkhead box protein N1 FOXN1 Tbio Transcription Factor -2.30206 196.4 204
Homeobox protein Hox-C13 HOXC13 Tbio Transcription Factor -1.59845 41.7 89