Development Level

Tbio 35 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
increased neutrophil cell numb... 1 | 46
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
small kidney 1 | 16

Disease

Carcinoma 28 | 11,493
psoriasis 25 | 6,694
ovarian cancer 22 | 8,520
glioblastoma 17 | 5,792
osteosarcoma 16 | 7,950
atypical teratoid / rhabdoid tumor 15 | 5,112
Astrocytoma, Pilocytic 14 | 3,081
ependymoma 14 | 4,679
Breast cancer 13 | 3,578
primitive neuroectodermal tumor 13 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
malignant mesothelioma 11 | 3,232
medulloblastoma, large-cell 11 | 6,241
lung cancer 10 | 4,740
non-small cell lung cancer 10 | 2,890
cystic fibrosis 9 | 1,696
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
group 3 medulloblastoma 8 | 4,104
pancreatic cancer 8 | 2,398
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
Autosomal recessive predisposition 7 | 1,442
Cryptorchidism 7 | 296
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
tuberculosis 7 | 2,010
Broad flat nasal bridge 6 | 236
Craniofacial Abnormalities 6 | 151
Muscle hypotonia 6 | 571
Nasal bridge wide 6 | 236
ductal carcinoma in situ 6 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Acquired scoliosis 5 | 281
Cancer 5 | 2,499
Congenital Epicanthus 5 | 177
Curvature of spine 5 | 282
Hereditary spherocytosis type 3 5 | 14
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Short neck 5 | 140
Short stature 5 | 531
Simpson-Golabi-Behmel syndrome 5 | 19
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
sonic hedgehog group medulloblastoma 5 | 467
Abnormality of the metaphyses 4 | 48
Anteverted nostril 4 | 191
Atopic dermatitis 4 | 952
Atrial Septal Defects 4 | 85
Big calvaria 4 | 147
Cleft Palate 4 | 271
Concave bridge of nose 4 | 195
Congenital clubfoot 4 | 109
Delayed bone age 4 | 136
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Downward slant of palpebral fissure 4 | 158
Generalized osteopenia 4 | 99
Hypoplastic mandible condyle 4 | 275
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Low-set, posteriorly rotated ears 4 | 110
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Orbital separation excessive 4 | 244
Osteopenia 4 | 99
Osteoporosis 4 | 363
Radioulnar synostosis 4 | 35
Umbilical hernia 4 | 93
Uranostaphyloschisis 4 | 167
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Dull intelligence 3 | 645
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Hepatomegaly 3 | 285
Mental and motor retardation 3 | 608
Micromelia 3 | 58
Seizures 3 | 596
Ventricular Septal Defects 3 | 119
aldosterone-producing adenoma 3 | 665
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Digestive Tract 38 | 17,369
Female tissues 38 | 17,400
Respiratory system 38 | 16,393
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Endocrine System 37 | 18,159
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Blood and immune system 36 | 16,909
Liver and Pancreas 36 | 16,750
Cardiovascular System 34 | 15,192

Target Family

Enzyme 25 | 4,145
Non-IDG 11 | 12,091
Kinase 1 | 634
Transporter 1 | 473

GO Process

glycosaminoglycan biosynthetic... 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Beta-1,3-galactosyltransferase 6 B3GALT6 Tbio Enzyme -1.00350 10.1 132
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 HS3ST3B1 Tbio Enzyme -0.73945 5.98 27
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 Tbio Enzyme -1.43805 32.2 112
Exostosin-2 EXT2 Tbio Enzyme -2.48068 279.7 154
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 Tbio Enzyme -0.79764 6.35 32
Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 Tbio Enzyme -2.99264 1021.1 225
Glypican-3 GPC3 Tbio Non-IDG -2.92699 862.1 768
Glypican-1 GPC1 Tbio Non-IDG -2.38207 232.3 202