Development Level

Tbio 16 | 10,625
Tchem 6 | 1,890
Tdark 2 | 7,003

IMPC Phenotype

decreased total body fat amoun... 4 | 186
increased lean body mass 2 | 107
abnormal heart left ventricle ... 1 | 20
abnormal retinal pigmentation 1 | 61
decreased NK T cell number 1 | 28
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating serum al... 1 | 79
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
increased NK T cell number 1 | 11
increased circulating alkaline... 1 | 119
increased circulating fructosa... 1 | 11
increased circulating serum al... 1 | 25
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased lymphocyte cell numb... 1 | 9
increased marginal zone B cell... 1 | 3
increased or absent threshold ... 1 | 128
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
thick ventricular wall 1 | 7
thin ventricular wall 1 | 5

Disease

ovarian cancer 12 | 8,491
lung cancer 8 | 4,473
malignant mesothelioma 7 | 3,163
psoriasis 7 | 6,685
Glycogen storage disease 6 | 37
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
medulloblastoma, large-cell 6 | 6,234
osteosarcoma 6 | 7,933
pancreatic cancer 6 | 2,300
Myocardial Ischemia 5 | 169
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
Cancer 4 | 2,346
astrocytic glioma 4 | 2,241
glioblastoma 4 | 5,572
lung adenocarcinoma 4 | 2,714
Breast cancer 3 | 3,098
Congenital hemolytic anemia 3 | 31
Diabetes Mellitus, Experimental 3 | 106
Multiple myeloma 3 | 1,327
cystic fibrosis 3 | 1,670
dermatomyositis 3 | 966
ependymoma 3 | 2,514
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
invasive ductal carcinoma 3 | 2,950
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287
Charcot-Marie-Tooth disease 2 | 74
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Gestational Diabetes 2 | 17
Hemolytic anemia 2 | 70
Hypoglycemia 2 | 81
Male infertility 2 | 170
Mouth Neoplasms 2 | 44
Myoglobinuria 2 | 11
Neurodegenerative disease 2 | 383
Neuropathy 2 | 210
Obesity 2 | 616
Osteoporosis 2 | 259
Squamous cell carcinoma 2 | 96
Stomach Neoplasms 2 | 282
Type 2 diabetes mellitus 2 | 192
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 785
acute quadriplegic myopathy 2 | 1,157
atypical teratoid / rhabdoid tumor 2 | 4,369
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
colon cancer 2 | 1,475
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
facioscapulohumeral dystrophy 2 | 286
fructose-1,6-bisphosphatase deficiency 2 | 8
juvenile dermatomyositis 2 | 1,189
mucosa-associated lymphoid tissue lymphoma 2 | 480
nephrosclerosis 2 | 329
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
primitive neuroectodermal tumor 2 | 3,031
spina bifida 2 | 1,064
tuberculosis and treatment for 3 months 2 | 327
Adenocarcinoma 1 | 115
Adenocarcinoma of lung (disorder) 1 | 48
Amyloidosis 1 | 68
Animal Mammary Neoplasms 1 | 135
Autoimmune polyendocrine syndrome type 1 1 | 7
Cryptosporidiosis 1 | 12
Diabetes Mellitus, Insulin-Dependent 1 | 77
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Diarrhea 1 | 155
Galactosemia 1 | 20
Giardiasis 1 | 10
Hyperglycemia 1 | 120
Hyperinsulinism 1 | 63
Hypermethioninemia 1 | 12
Hyperuricemia 1 | 35
Irritable bowel syndrome 1 | 59
Lactose intolerance 1 | 7
Liver Cirrhosis, Experimental 1 | 108
Mammary Neoplasms, Experimental 1 | 149
Menkes disease 1 | 20
Myocardial Infarction 1 | 126
Neoplasm Invasiveness 1 | 127
Polycythemia 1 | 19
Prostate carcinoma in situ 1 | 11
Renal tubular acidosis 1 | 14
Squamous cell carcinoma of esophagus 1 | 82
Tropical sprue 1 | 5
Type 1 diabetes mellitus 1 | 104
Tyrosinemia 1 | 12
Wilson disease 1 | 16
maturity-onset diabetes of the young 1 | 30
non-inflammatory breast cancer 1 | 208

Tissue

Blood and immune system 24 | 17,994
Cardiovascular System 24 | 17,957
Digestive Tract 24 | 18,472
Endocrine System 24 | 18,511
Female tissues 24 | 18,646
Liver and Pancreas 24 | 18,135
Male tissues 24 | 17,968
Nervous System 24 | 18,560
Respiratory system 24 | 17,483
Skin and soft tissues 24 | 18,114
Urinary Tract 24 | 18,443

Target Family

Enzyme 13 | 4,146
Kinase 11 | 634

GO Process

glycolytic process 24 | 24
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphoglycerate mutase 2 PGAM2 Tbio Enzyme -1.54638 36.2 160
Hexokinase-2 HK2 Tchem Kinase -2.60415 391.1 373
Phosphoglycerate mutase 1 PGAM1 Tbio Enzyme -1.74935 55.3 185
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.68147 478.5 119
Glucokinase GCK Tchem Kinase -2.88674 738.6 291
Putative hexokinase HKDC1 HKDC1 Tchem Kinase -0.65835 4.71 84
Triosephosphate isomerase TPI1 Tbio Enzyme -2.85904 704.6 261
ATP-dependent 6-phosphofructokinase, muscle type PFKM Tbio Kinase -2.48787 295.5 251
Phosphoglycerate kinase 2 PGK2 Tbio Kinase -1.83180 68.0 130
Bisphosphoglycerate mutase BPGM Tbio Enzyme -1.26416 17.9 163