Development Level

Tbio 10 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal tooth morphology 1 | 24
decreased body weight 1 | 161
decreased hemoglobin content 1 | 68
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to t... 1 | 278
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 15 | 11,493
ovarian cancer 12 | 8,520
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 9 | 7,950
lung cancer 8 | 4,740
glioblastoma 7 | 5,792
Autosomal recessive predisposition 6 | 1,442
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
psoriasis 6 | 6,694
Cognitive delay 5 | 608
Epilepsy 5 | 792
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
subependymal giant cell astrocytoma 5 | 2,287
Breast cancer 4 | 3,578
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Poor school performance 4 | 645
Seizures 4 | 596
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
Cancer 3 | 2,499
Cerebellar Ataxia 3 | 304
Failure to gain weight 3 | 365
Hyperammonemia 3 | 30
Infantile onset 3 | 238
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
gastric cancer 3 | 459
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
primitive neuroectodermal tumor 3 | 3,035
Abnormality of metabolism/homeostasis 2 | 134
Autistic Disorder 2 | 364
Blepharoptosis 2 | 231
Byzanthine arch palate 2 | 194
Delayed speech and language development 2 | 112
Dilated ventricles (finding) 2 | 121
Electroencephalogram abnormal 2 | 101
Feeding difficulties 2 | 127
Hyperreflexia 2 | 209
Hypoplastic mandible condyle 2 | 275
Kidney cancer 2 | 2,613
Language Delay 2 | 112
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Liver Cirrhosis, Experimental 2 | 769
Macrotia 2 | 87
Mandibular hypoplasia 2 | 275
Microcephaly 2 | 166
Motor delay 2 | 147
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
No development of motor milestones 2 | 147
Progressive disorder 2 | 142
Psychotic Disorders 2 | 151
Skeletal muscle atrophy 2 | 139
Small head 2 | 374
Speech Delay 2 | 112
Speech impairment 2 | 112
Steatorrhea 2 | 34
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
muscle degeneration 2 | 139
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Respiratory system 15 | 16,393

Target Family

Enzyme 14 | 4,145
Epigenetic 1 | 242
Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

GO Process

glutamine metabolic process 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Phosphoribosylformylglycinamidine synthase PFAS Tbio Enzyme -2.83741 653.1 88
Asparagine synthetase domain-containing protein 1 ASNSD1 Tdark Enzyme 1.41 0.02 103
GMP synthase [glutamine-hydrolyzing] GMPS Tbio Enzyme -2.48490 295.1 194
Succinate-semialdehyde dehydrogenase, mitochondrial ALDH5A1 Tclin Enzyme -2.23586 168.4 347
CAD protein CAD Tchem Non-IDG -2.23887 168.4 224
Asparagine synthetase [glutamine-hydrolyzing] ASNS Tchem Enzyme -2.40144 244.3 223
Glycine N-acyltransferase-like protein 1 GLYATL1 Tbio Enzyme -2.19209 154.4 55
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.39787 257.7 148
Carbamoyl-phosphate synthase [ammonia], mitochondrial CPS1 Tclin Enzyme -2.28267 188.9 238