Development Level

Tclin 11 | 602
Tbio 4 | 10,625

Collection

Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

abnormal behavior 1 | 226
abnormal gait 1 | 51
decreased circulating alanine ... 1 | 53
enlarged heart 1 | 111
hyperactivity 1 | 108
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38

Disease

atypical teratoid / rhabdoid tumor 12 | 4,369
medulloblastoma, large-cell 12 | 6,234
glioblastoma 11 | 5,572
psoriasis 11 | 6,685
Carcinoma 10 | 2,147
Schizophrenia 10 | 503
oligodendroglioma 9 | 2,849
primitive neuroectodermal tumor 9 | 3,031
Epilepsy 8 | 346
Lennox-Gastaut syndrome 8 | 34
Simple partial seizure 8 | 26
astrocytic glioma 8 | 2,241
osteosarcoma 8 | 7,933
ependymoma 7 | 2,514
lung carcinoma 7 | 2,844
ovarian cancer 7 | 8,491
pilocytic astrocytoma 7 | 3,086
Bipolar Disorder 6 | 266
Epilepsy characterized by intractable complex partial seizures 6 | 28
Migraine Prevention 6 | 22
Pick disease 6 | 1,893
Tonic-clonic epilepsy 6 | 47
adult high grade glioma 6 | 2,148
pediatric high grade glioma 6 | 2,712
General anesthesia 5 | 53
Local anesthesia 5 | 40
group 4 medulloblastoma 5 | 1,875
lung cancer 5 | 4,473
medulloblastoma 5 | 1,524
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 320
Intellectual disability 4 | 573
Alcohol dependence 3 | 107
Alcoholism 3 | 14
Arteriosclerotic Parkinsonism 3 | 8
Breast cancer 3 | 3,098
Extrapyramidal disease 3 | 8
Huntington's disease 3 | 72
Influenza A Prevention 3 | 7
Influenza due to Influenza A virus 3 | 7
Major Depressive Disorder 3 | 106
Neurodegenerative disease 3 | 383
Parkinson's disease 3 | 364
Parkinsonism 3 | 19
Postencephalitic parkinsonism 3 | 12
Toxic encephalopathy 3 | 131
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Attention deficit hyperactivity disorder 2 | 156
Brain Ischemia 2 | 87
Cancer 2 | 2,346
Cerebrovascular disease 2 | 231
Craniofacial Abnormalities 2 | 147
Down syndrome 2 | 548
Fetal alcohol syndrome 2 | 10
Melanoma 2 | 261
Moderate to Severe Alzheimer's Type Dementia 2 | 5
Opiate dependence 2 | 12
Partial seizure 2 | 15
Psychosexual Disorders 2 | 6
Rheumatoid Arthritis 2 | 1,170
Skin cancer 2 | 37
Substance-Related Disorders 2 | 114
West Syndrome 2 | 24
gastric carcinoma 2 | 832
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,714
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
obsessive-compulsive disorder 2 | 34
progressive supranuclear palsy 2 | 674
sarcoidosis 2 | 368
tuberculosis and treatment for 3 months 2 | 327
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Amenorrhea 1 | 60
Brain disease 1 | 84
Cerebellar Ataxia 1 | 72
Child Development Disorders, Pervasive 1 | 55
Colorectal Neoplasms 1 | 217
Congenital Heart Defects 1 | 37
Early infantile epileptic encephalopathy with suppression bursts 1 | 18
Encephalitis 1 | 54
Fragile X syndrome 1 | 31
Impotence 1 | 45
Language Development Disorders 1 | 9
Learning disability 1 | 20
Liver cancer 1 | 31
Long QT syndrome 1 | 53
MYELODYSPLASTIC SYNDROME 1 | 39
Muscle Weakness 1 | 92
Myopia 1 | 99
Osteoporosis 1 | 259
Refractive Errors 1 | 18

Tissue

Blood and immune system 15 | 17,994
Cardiovascular System 15 | 17,957
Digestive Tract 15 | 18,472
Endocrine System 15 | 18,511
Female tissues 15 | 18,646
Liver and Pancreas 15 | 18,135
Male tissues 15 | 17,968
Nervous System 15 | 18,560
Respiratory system 15 | 17,483
Skin and soft tissues 15 | 18,114
Urinary Tract 15 | 18,443

Target Family

Ion Channel 11 | 341
Enzyme 1 | 4,146
Epigenetic 1 | 242
GPCR 1 | 408
Non-IDG 1 | 11,969

GO Process

glutamate receptor signaling p... 15 | 15
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.13194 126.3 290
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.02679 111.0 70
Glutamate receptor 3 GRIA3 Tclin Ion Channel -1.95421 83.7 203
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.49899 328.4 157
Glutamate receptor ionotropic, kainate 2 GRIK2 Tclin Ion Channel -2.42011 265.6 219
Glutamate receptor ionotropic, kainate 3 GRIK3 Tclin Ion Channel -1.48916 28.2 125
Glutamate receptor ionotropic, kainate 4 GRIK4 Tclin Ion Channel -2.17439 139.3 91
Glutamate receptor 4 GRIA4 Tclin Ion Channel -2.42299 246.0 294
Synaptic functional regulator FMR1 FMR1 Tbio Epigenetic -3.36032 2331.5 449
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.07842 1098.2 460