Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
osteosarcoma 4 | 7,950
subependymal giant cell astrocytoma 4 | 2,287
Down syndrome 3 | 499
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Cancer 2 | 2,499
Generalized dystonia 2 | 4
Heart disease 2 | 306
Hypoglycemia 2 | 152
Liver Cirrhosis, Experimental 2 | 769
astrocytic glioma 2 | 2,597
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
Abortion, Spontaneous 1 | 109
Acute endometritis 1 | 1
Alzheimer's disease 1 | 658
Anhedonia 1 | 27
Ataxia, Truncal 1 | 21
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Bilirubin metabolic disorder 1 | 41
Bipolar Disorder 1 | 666
Chromosome 5p13 duplication syndrome 1 | 2
Congenital myasthenic syndrome 10 1 | 8
D-2-hydroxyglutaric aciduria 1 | 9
Degenerative polyarthritis 1 | 115
Dicarboxylic aminoaciduria 1 | 4
Dull intelligence 1 | 645
Epilepsy 1 | 792
Episodic ataxia 1 | 22
Glaucoma 1 | 239
Hemiparesis 1 | 34
Hemiplegia 1 | 25
Hyperammonemia 1 | 30
Hyperglycemia 1 | 137
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemic hypoglycemia 1 | 17
Hyperinsulinism 1 | 133
Hypertension 1 | 396
Hypoglycaemic seizure 1 | 10
Hypoglycemic coma 1 | 10
Intermittent migraine headaches 1 | 68
Juvenile dermatitis herpetiformis 1 | 1
Kidney cancer 1 | 2,613
L-2-hydroxyglutaric aciduria 1 | 8
Migraine Disorders 1 | 76
Multiple myeloma 1 | 1,332
Neonatal Jaundice 1 | 30
Neurodegenerative disease 1 | 414
Osteoarthritis 1 | 184
PARKINSON DISEASE, LATE-ONSET 1 | 20
Polyhydramnios 1 | 108
Poor school performance 1 | 645
Rheumatoid arthritis 1 | 1,191
Seizures 1 | 596
Slurred speech 1 | 7
Spontaneous abortion 1 | 113
Stomach carcinoma in situ 1 | 2
Toxic encephalopathy 1 | 141
Vascular disease 1 | 319
Wernicke encephalopathy 1 | 12
active Crohn's disease 1 | 922
aldosterone-producing adenoma 1 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
cystic fibrosis 1 | 1,696
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
fibroadenoma 1 | 559
gastric cancer 1 | 459
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 4 | 4,145
Transporter 1 | 473

GO Process

glutamate biosynthetic process 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Glutaminase kidney isoform, mitochondrial GLS Tchem Enzyme -2.92171 795.3 268
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.39787 257.7 148
Excitatory amino acid transporter 1 SLC1A3 Tchem Transporter -2.76402 569.7 221
Glutamate dehydrogenase 2, mitochondrial GLUD2 Tbio Enzyme -1.21617 14.6 164