Development Level

Tbio 35 | 11,445
Tchem 10 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal QT variability 2 | 10
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased or absent threshold ... 1 | 101
mammalian phenotype 1 | 17

Disease

Carcinoma 31 | 11,493
ovarian cancer 25 | 8,520
psoriasis 22 | 6,694
Autosomal recessive predisposition 18 | 1,442
atypical teratoid / rhabdoid tumor 18 | 5,112
lung cancer 18 | 4,740
glioblastoma 17 | 5,792
osteosarcoma 17 | 7,950
invasive ductal carcinoma 15 | 2,951
non-small cell lung cancer 15 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
medulloblastoma, large-cell 14 | 6,241
astrocytic glioma 13 | 2,597
lung adenocarcinoma 13 | 2,716
Cancer 12 | 2,499
ependymoma 12 | 4,679
malignant mesothelioma 12 | 3,232
Liver Cirrhosis, Experimental 11 | 769
Schizophrenia 10 | 1,160
adrenocortical carcinoma 10 | 1,428
adult high grade glioma 10 | 3,801
breast carcinoma 10 | 1,638
diabetes mellitus 10 | 1,728
ductal carcinoma in situ 10 | 1,745
primitive neuroectodermal tumor 10 | 3,035
Breast cancer 9 | 3,578
Multiple myeloma 9 | 1,332
Obesity 9 | 678
Pick disease 9 | 1,894
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Epilepsy 8 | 792
Liver carcinoma 8 | 240
acute quadriplegic myopathy 8 | 1,158
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung carcinoma 8 | 2,843
nephrosclerosis 8 | 333
Astrocytoma, Pilocytic 7 | 3,081
Glycogen storage disease 7 | 39
Hypoglycemia 7 | 152
Seizures 7 | 596
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
Hepatomegaly 6 | 285
Hyperglycemia 6 | 137
Osteoporosis 6 | 363
Waldenstrons macroglobulinemia 6 | 765
cystic fibrosis 6 | 1,696
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
Alzheimer's disease 5 | 658
Animal Mammary Neoplasms 5 | 136
Bipolar Disorder 5 | 666
Carcinoma, Hepatocellular 5 | 228
Cognitive delay 5 | 608
Congenital hemolytic anemia 5 | 32
Depressive disorder 5 | 409
Elevated hepatic transaminases 5 | 81
Fatty liver disease 5 | 103
Global developmental delay 5 | 608
Hepatic enzyme increased 5 | 81
Icterus 5 | 82
Liver Dysfunction 5 | 99
Liver enzymes abnormal 5 | 81
Liver function test increased 5 | 81
Liver function tests abnormal finding 5 | 81
Mammary Neoplasms, Animal 5 | 136
Mammary Neoplasms, Experimental 5 | 154
Mental and motor retardation 5 | 608
Rheumatoid arthritis 5 | 1,191
Steatohepatitis 5 | 44
Stomach Neoplasms 5 | 300
Subclinical abnormal liver function tests 5 | 81
Transaminases increased 5 | 81
colon cancer 5 | 1,478
ulcerative colitis 5 | 1,819
Acidosis, Lactic 4 | 97
Adenocarcinoma of lung 4 | 142
Atopic dermatitis 4 | 952
Chemical and Drug Induced Liver Injury 4 | 195
Cholecystitis 4 | 18
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Heart failure 4 | 162
Hypoxia 4 | 33
Lactic acidemia 4 | 95
Lactic acidosis 4 | 51
Low intelligence 4 | 645
Mental Depression 4 | 333
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Mouth Neoplasms 4 | 55
Poor school performance 4 | 645
Short stature 4 | 531
Splenomegaly 4 | 190
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
fibroadenoma 4 | 559
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187

Tissue

Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Blood and immune system 43 | 16,909
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Cardiovascular System 41 | 15,192
Respiratory system 40 | 16,393

Target Family

Enzyme 28 | 4,145
Transporter 6 | 473
Non-IDG 5 | 12,091
Kinase 4 | 634
Transcription Factor 2 | 1,400

GO Process

gluconeogenesis 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glucose-6-phosphatase 3 G6PC3 Tbio Enzyme -1.55249 37.2 54
Malate dehydrogenase, mitochondrial MDH2 Tchem Enzyme -2.25018 186.1 256
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Phosphoglycerate kinase 1 PGK1 Tchem Kinase -2.79738 602.5 340
Glucose-6-phosphate exchanger SLC37A4 SLC37A4 Tchem Transporter 0.00000 0
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.64656 428.3 291
Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 Tbio Transporter -1.72278 56.8 134
Triosephosphate isomerase TPI1 Tbio Enzyme -2.88127 742.8 315
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] PCK1 Tbio Kinase -2.33937 203.6 442
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.68870 491.5 141