Development Level

Tbio 4 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal eye morphology 1 | 68
decreased circulating creatini... 1 | 39
decreased grip strength 1 | 116
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 7 | 8,520
Carcinoma 6 | 11,493
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
Cancer 4 | 2,499
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Vesico-Ureteral Reflux 3 | 33
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Abnormal cortical bone morphology 2 | 22
Agenesis of corpus callosum 2 | 83
Byzanthine arch palate 2 | 194
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Craniofacial Abnormalities 2 | 151
Dilated ventricles (finding) 2 | 121
Ectopic Tissue 2 | 14
Frontal lobe hypoplasia 2 | 9
Glaucoma 2 | 239
Global developmental delay 2 | 608
Hyperreflexia 2 | 209
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 2 | 16
Mental and motor retardation 2 | 608
Mesothelioma, Malignant 2 | 105
Microcephaly 2 | 166
Pachygyria 2 | 41
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Severe mental retardation (I.Q. 20-34) 2 | 99
Short stature 2 | 531
Sloping forehead 2 | 46
Small head 2 | 374
Thin upper lip vermilion 2 | 67
Unilateral agenesis of kidney 2 | 20
Upward slant of palpebral fissure 2 | 75
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
non-small cell lung carcinoma 2 | 317
subependymal giant cell astrocytoma 2 | 2,287
Abnormal brain FDG positron emission tomography 1 | 9
Aortic Aneurysm, Thoracic 1 | 8
Autosomal dominant nonsyndromic deafness 10 1 | 4
Autosomal dominant nonsyndromic deafness 23 1 | 3
Behavioral variant of frontotemporal dementia 1 | 8
Blurred vision 1 | 19
Bone Diseases, Developmental 1 | 27
Branchioma 1 | 3
Chromosome Aberrations 1 | 16
Compulsive hoarding 1 | 7
Deep overbite 1 | 4
Developmental arithmetic disorder 1 | 8
Difficulty making arithmetical calculations 1 | 8
Dissection of aorta 1 | 9
Duodenal Ulcer due to H. Pylori 1 | 7
Duodenal ulcer disease 1 | 7
Dysphasia 1 | 23
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Erosive esophagitis 1 | 6
Frontotemporal cerebral atrophy 1 | 8
Gastric Hypersecretory Conditions 1 | 5
Gastric ulcer 1 | 33
Hyperorality 1 | 7
Hypoplastic cochlea 1 | 6
Incomplete partition of the cochlea type II 1 | 3
Learning Disorders 1 | 29
Macular holes 1 | 11
Maintenance of Healing Duodenal Ulcer 1 | 7
Middle ear malformations 1 | 5
Mondini malformation 1 | 3
Mutism 1 | 17
Narrowing of ear canal 1 | 13
Overbite 1 | 4
Peptic Ulcer 1 | 27
Posterior lingual occlusion of mandibular teeth 1 | 4
Posterior polar cataract 1 | 6
Renal hypoplasia/aplasia 1 | 7
Repeated speech 1 | 9
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Stenosis of external auditory canal 1 | 13
Thoracic aortic aneurysm 1 | 15
Zollinger-Ellison syndrome 1 | 18

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192

Target Family

Non-IDG 3 | 12,091
Kinase 2 | 634
Transcription Factor 2 | 1,400

GO Process

generation of neurons 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
THO complex subunit 2 THOC2 Tbio Non-IDG -1.89777 77.8 44
Citron Rho-interacting kinase CIT Tchem Kinase -0.69610 4.69 117
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
Microtubule-associated protein tau MAPT Tchem Non-IDG -3.88207 7239.3 3951
Homeobox protein SIX1 SIX1 Tbio Transcription Factor -2.64041 433.7 111