Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal embryo size 2 | 220
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased circulating alkaline... 1 | 46
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
increased bone mineral density 1 | 72
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 15 | 11,493
osteosarcoma 9 | 7,950
atypical teratoid / rhabdoid tumor 8 | 5,112
ovarian cancer 8 | 8,520
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
Cancer 6 | 2,499
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
interstitial cystitis 4 | 2,312
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Liver cancer 3 | 604
Short stature 3 | 531
Small head 3 | 374
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
Abdominal Pain 2 | 98
Adenoma 2 | 167
Alopecia 2 | 115
Biliary tract cancer 2 | 19
Breast Neoplasms 2 | 445
Class III malocclusion 2 | 78
Colorectal Neoplasms 2 | 243
Conductive hearing loss 2 | 123
Congenital deafness 2 | 185
Craniofacial Abnormalities 2 | 151
Deafness 2 | 198
Decreased joint mobility 2 | 53
Dull intelligence 2 | 645
Endometrial cancer 2 | 311
Esophageal carcinoma 2 | 16
Familial adenomatous polyposis 2 | 32
Glioma 2 | 74
Headache 2 | 37
Hearing Loss, Partial 2 | 185
Hypertrophy of lower jaw 2 | 78
Increased size of mandible 2 | 78
Increased thickness of cranium 2 | 17
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Liver neoplasms 2 | 130
Low intelligence 2 | 645
Mammary Neoplasms 2 | 425
Mandibular hyperplasia 2 | 78
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Metaphyseal widening 2 | 22
Multiple synostoses syndrome 2 | 9
Multiple, subcutaneous nodules 2 | 53
Muscle hypotonia 2 | 571
Myopathy 2 | 185
Orbital separation excessive 2 | 244
Osteoporosis 2 | 363
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Platyspondyly 2 | 56
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
Somatic mutation 2 | 61
Stomach Neoplasms 2 | 300
Stomach cancer 2 | 30
Strabismus 2 | 270
Subcutaneous nodule 2 | 53
Thickened calvaria 2 | 17
Thin upper lip vermilion 2 | 67
Thyroid cancer 2 | 36
Ventricular Septal Defects 2 | 119
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
group 3 medulloblastoma 2 | 4,104
hearing impairment 2 | 199
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
mandibular excess (physical finding) 2 | 78
non-small cell lung cancer 2 | 2,890
osteoporosis-pseudoglioma syndrome 2 | 9
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Exudative vitreoretinopathy 1 | 15
Renal fibrosis 1 | 6
Retinitis pigmentosa 32 1 | 1
Subcapsular cataract 1 | 5
Thickened cortex of long bones 1 | 4

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400

GO Process

gastrulation with mouth formin... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Teneurin-4 TENM4 Tbio Non-IDG -1.41343 23.9 19
Angiomotin AMOT Tbio Non-IDG -1.75932 64.8 318
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
Chordin CHRD Tbio Non-IDG -2.33214 201.6 198
LIM/homeobox protein Lhx1 LHX1 Tbio Transcription Factor -1.69625 49.3 365
UDP-glucose 6-dehydrogenase UGDH Tbio Enzyme -2.38443 245.9 221
Zinc finger and BTB domain-containing protein 17 ZBTB17 Tbio Transcription Factor -1.57508 40.4 92
Activin receptor type-2B ACVR2B Tchem Kinase -2.14321 122.9 303