Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal pericardium morpholog... 1 | 26
edema 1 | 59
embryonic lethality prior to t... 1 | 278

Disease

ovarian cancer 7 | 8,520
Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
osteosarcoma 5 | 7,950
primitive neuroectodermal tumor 5 | 3,035
Cancer 4 | 2,499
Oculodentodigital dysplasia 4 | 14
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
pancreatic cancer 4 | 2,398
Erythrokeratodermia variabilis 3 | 10
Hypertension 3 | 396
Hypertensive disease 3 | 292
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Adenoma 2 | 167
Alopecia 2 | 115
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Bilateral fifth finger clinodactyly 2 | 110
Cardiomyopathy 2 | 116
Clouston syndrome 2 | 9
Conductive hearing loss 2 | 123
Congenital pes cavus 2 | 88
Cortical white matter abnormalities seen on MRI 2 | 18
Curvature of little finger 2 | 110
Deafness, autosomal recessive 1A 2 | 4
Dull intelligence 2 | 645
Dysarthria 2 | 192
Dystrophic fingernails 2 | 18
Erythema 2 | 58
Fine hair 2 | 42
First degree atrioventricular block 2 | 5
Flushing 2 | 60
Frontal bossing 2 | 157
Heart disease 2 | 306
Hyperkeratosis, generalized 2 | 14
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Leukoaraiosis 2 | 18
Low Vision 2 | 174
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Nail dysplasia 2 | 52
Neuropathy 2 | 261
Palmoplantar keratosis 2 | 74
Paraparesis 2 | 6
Poor school performance 2 | 645
Sinoatrial node disease 2 | 5
Skin Neoplasms 2 | 69
Small head 2 | 374
Sparse eyelashes 2 | 31
Sparse hair 2 | 59
Thin lips 2 | 49
Thin, sparse hair 2 | 59
Visual Impairment 2 | 174
X- linked recessive 2 | 110
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318
Abnormality of the nasopharynx 1 | 9
Bulbous internal auditory canal 1 | 5
Chromosome 1q21.1 Deletion Syndrome, 1.35-Mb 1 | 2
Congenital hypoplasia of aortic arch 1 | 2
Endocardial Fibroelastosis 1 | 9
Fleshy earlobes 1 | 8
Hidradenitis suppurativa 1 | 13
Hyperplasia of permanent maxillary central incisor 1 | 3
Hypertrophy of craniofacial bones 1 | 11
Hypertrophy of permanent maxillary central incisor 1 | 3
Increased size of permanent maxillary central incisor 1 | 3
Progressive hearing loss stapes fixation 1 | 3
Prominent, protruding upper incisors 1 | 3
Stapes ankylosis 1 | 4

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 8 | 12,091

GO Process

gap junction assembly 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-1 protein GJB1 Tbio Non-IDG -2.93115 861.6 295
Gap junction delta-3 protein GJD3 Tbio Non-IDG -0.48785 4.49 23
Catenin alpha-1 CTNNA1 Tbio Non-IDG -1.94479 78.1 488
Gap junction gamma-1 protein GJC1 Tbio Non-IDG -2.29774 186.2 236
Gap junction alpha-1 protein GJA1 Tbio Non-IDG -3.59195 4122.5 889