Development Level

Tclin 2 | 613

Disease

Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Carcinoma 2 | 11,493
Cognitive delay 2 | 608
Epilepsy 2 | 792
Epilepsy characterized by intractable complex partial seizures 2 | 28
Global developmental delay 2 | 608
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Succinic semialdehyde dehydrogenase deficiency 2 | 16
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal behavior 1 | 52
Abnormal ocular motility 1 | 19
Abnormality of metabolism/homeostasis 1 | 134
Absence Epilepsy 1 | 22
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Anxiety 1 | 136
Anxiety disease 1 | 113
Bipolar affective disorder, current episode manic 1 | 13
Breast cancer 1 | 3,578
Cardiovascular system disease 1 | 246
Chronic Lymphocytic Leukemia 1 | 262
Death in childhood 1 | 14
Decreased tendon reflex 1 | 122
Delayed speech and language development 1 | 112
Downward slant of palpebral fissure 1 | 158
Dystonia Disorders 1 | 6
Dystonic Disorders 1 | 7
Electroencephalogram abnormal 1 | 101
Epilepsies, Myoclonic 1 | 32
Gastroesophageal reflux disease 1 | 110
Generalized myoclonic seizures 1 | 30
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hyperactive behavior 1 | 91
Hyperreflexia 1 | 209
Hypotonia, severe 1 | 33
Infantile onset 1 | 238
Kidney cancer 1 | 2,613
Language Delay 1 | 112
Lethargy 1 | 77
Leukodystrophy 1 | 55
Liver Cirrhosis, Experimental 1 | 769
Motor delay 1 | 147
Myoclonic Epilepsies, Progressive 1 | 44
No development of motor milestones 1 | 147
Paraplegia 1 | 74
Peroneal nerve paralysis 1 | 11
Phenotypic variability 1 | 150
Physical aggression 1 | 76
Pick disease 1 | 1,894
Posterior fossa cyst 1 | 8
Psychomotor Disorders 1 | 7
Psychotic Disorders 1 | 151
Retrognathia 1 | 54
Seizures 1 | 596
Self-Injurious Behavior 1 | 12
Speech Delay 1 | 112
Speech impairment 1 | 112
Status Epilepticus 1 | 98
Tall stature 1 | 34
Tonic - clonic seizures 1 | 44
Waldenstrons macroglobulinemia 1 | 765
West Syndrome 1 | 28
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
fibroadenoma 1 | 559
gastric cancer 1 | 459
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
pancreatic cancer 1 | 2,398
pituitary cancer 1 | 1,972
primary Sjogren syndrome 1 | 735
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
subependymal giant cell astrocytoma 1 | 2,287
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

GO Process

gamma-aminobutyric acid catabo... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Succinate-semialdehyde dehydrogenase, mitochondrial ALDH5A1 Tclin Enzyme -2.23586 168.4 347
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204