Development Level

Tbio 10 | 11,445
Tdark 6 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
embryonic lethality prior to t... 2 | 278
increased startle reflex 2 | 112
abnormal allantois morphology 1 | 8
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal iris transilluminatio... 1 | 2
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal optic vesicle formati... 1 | 4
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitreous body morphol... 1 | 10
anophthalmia 1 | 33
cataract 1 | 92
cornea ulcer 1 | 1
corneal opacity 1 | 32
decreased body length 1 | 101
decreased body weight 1 | 161
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
female infertility 1 | 60
fused cornea and lens 1 | 5
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
iris synechia 1 | 3
male infertility 1 | 123
narrow eye opening 1 | 12
pale yolk sac 1 | 25

Disease

Carcinoma 10 | 11,493
ovarian cancer 6 | 8,520
glioblastoma 5 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Cancer 4 | 2,499
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
Autosomal recessive predisposition 3 | 1,442
Cryptorchidism 3 | 296
Intellectual disability 3 | 1,016
Pick disease 3 | 1,894
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
group 4 medulloblastoma 3 | 1,855
medulloblastoma, large-cell 3 | 6,241
Abnormally small eyeball 2 | 97
Acquired scoliosis 2 | 281
Almond-shaped eyes 2 | 23
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Birthmark 2 | 35
Cafe-au-Lait Spots 2 | 37
Chromosome Breakage 2 | 36
Cleft Lip 2 | 141
Cognitive delay 2 | 608
Congenital absence of kidney 2 | 31
Curvature of spine 2 | 282
Decreased platelet count 2 | 111
Decreased size of eyeball 2 | 97
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Esophageal atresia 2 | 43
Esophageal atresia with or without tracheoesophageal fistula 2 | 21
Fanconi anemia 2 | 56
Global developmental delay 2 | 608
Hemoglobin low 2 | 124
Increased chromosomal breakage 2 | 27
Irregular hyperpigmentation 2 | 33
Leukopenia 2 | 72
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microphthalmos 2 | 100
Poor school performance 2 | 645
Pyridoxine-responsive sideroblastic anemia 2 | 17
Radial aplasia/hypoplasia 2 | 29
Short palpebral fissure 2 | 38
Short stature 2 | 531
Small head 2 | 374
Thrombocytopenia 2 | 197
Tracheoesophageal Fistula 2 | 36
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
ependymoma 2 | 4,679
esophageal atresia/tracheoesophageal fistula 2 | 22
facioscapulohumeral dystrophy 2 | 288
hypopigmented skin patch 2 | 59
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
Abnormal pigmentation 1 | 25
Absence of radius and ulna 1 | 15
Absent radius 1 | 15
Aplasia/Hypoplasia involving the nose 1 | 5
Azoospermia 1 | 110
Celiac disease 1 | 116
Chemical and Drug Induced Liver Injury 1 | 195
Cleft palate with cleft lip 1 | 23
Congenital Heart Defects 1 | 58
Congenital deafness 1 | 185
Congenital heart disease 1 | 93
Congenital hypoplasia of nose 1 | 5
Contagious pustular dermatitis 1 | 11
Deafness 1 | 198
Eastern equine encephalitis 1 | 16
Ecchymosis 1 | 66
Eclampsia 1 | 6
Epidermodysplasia verruciformis 1 | 21
Hearing Loss, Partial 1 | 185
Horseshoe Kidney 1 | 16
Hypospadias 1 | 53
Hypotrophic nose 1 | 5
Increased tendency to bruise 1 | 66
Neutrophil count decreased 1 | 47
Oral cleft 1 | 18
Primary hypogonadism 1 | 37
Radial aplasia 1 | 15
X-linked cerebral adrenoleukodystrophy 1 | 116
chronic kidney disease 1 | 90
hearing impairment 1 | 199
sarcoidosis 1 | 370

Tissue

Endocrine System 17 | 18,159
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 10 | 12,091
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145
Nuclear Receptor 1 | 48

GO Process

gamete generation 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase FANCL FANCL Tbio Enzyme -2.46302 286.2 146
Gametogenetin GGN Tbio Non-IDG -2.15183 135.1 57
Spindlin-2A SPIN2A Tdark Non-IDG -1.44354 24.2 32
Rhox homeobox family member 1 RHOXF1 Tbio Transcription Factor -0.75150 5.38 106
Fanconi anemia group D2 protein FANCD2 Tbio Non-IDG -2.59123 391.6 404
Krueppel-like factor 17 KLF17 Tbio Transcription Factor -1.18669 18.8 137
Nuclear receptor subfamily 6 group A member 1 NR6A1 Tbio Nuclear Receptor -2.36193 227.5 236
Gap junction alpha-10 protein GJA10 Tdark Non-IDG 0.15 0.90 51
Spindlin-1 SPIN1 Tbio Non-IDG -2.02987 109.3 128
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.77339 65.4 193