Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal QT variability 2 | 10
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal retinal vasculature m... 1 | 27
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
increased body temperature 1 | 9
increased circulating alkaline... 1 | 122
increased or absent threshold ... 1 | 101

Disease

psoriasis 5 | 6,694
lung cancer 4 | 4,740
Autosomal recessive predisposition 3 | 1,442
Carcinoma 3 | 11,493
ductal carcinoma in situ 3 | 1,745
fructose-1,6-bisphosphatase deficiency 3 | 7
ovarian cancer 3 | 8,520
Cancer 2 | 2,499
Comatose 2 | 56
Epilepsy 2 | 792
Glycogen storage disease 2 | 39
Hepatomegaly 2 | 285
Hypoglycemia 2 | 152
Icterus 2 | 82
Lethargy 2 | 77
Metabolic acidosis 2 | 90
Prostate carcinoma in situ 2 | 11
Schizophrenia 2 | 1,160
Seizures 2 | 596
Stomach Neoplasms 2 | 300
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
Abdominal Pain 1 | 98
Acidosis, Lactic 1 | 97
Adenocarcinoma of lung 1 | 142
Autoimmune polyendocrine syndrome type 1 1 | 9
Blepharoptosis 1 | 231
Borna disease 1 | 6
Breast Neoplasms 1 | 445
Carcinoma, Hepatocellular 1 | 228
Chemical and Drug Induced Liver Injury 1 | 195
Cholecystitis 1 | 18
Colonic Neoplasms 1 | 142
Congenital Epicanthus 1 | 177
Congenital hemolytic anemia 1 | 32
Cystinosis 1 | 14
Delayed Puberty 1 | 97
Dyspnea 1 | 76
Elevated heart rate 1 | 25
Elevated hepatic transaminases 1 | 81
Failure to gain weight 1 | 365
Fanconi syndrome 1 | 14
Fever 1 | 138
Galactosemia 1 | 19
Hepatic enzyme increased 1 | 81
Hypermethioninemia 1 | 11
Hyperuricemia 1 | 49
Hyperventilation 1 | 6
Hypophosphatemia 1 | 40
Hypoxia 1 | 33
Increased bilirubin level (finding) 1 | 18
Irritable bowel syndrome 1 | 60
Ketonemia 1 | 11
Ketosis 1 | 11
Lactic acidemia 1 | 95
Lactic acidosis 1 | 51
Lactose intolerance 1 | 7
Liver Cirrhosis 1 | 181
Liver Dysfunction 1 | 99
Liver carcinoma 1 | 240
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low posterior hairline 1 | 52
Lymphoid leukemia 1 | 160
Malnutrition 1 | 11
Mammary Neoplasms 1 | 425
Mood Disorders 1 | 184
Nausea 1 | 20
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Parkinson Disease 1 | 64
Pediatric failure to thrive 1 | 365
Renal Tubular Acidosis, Type II 1 | 4
Renal tubular acidosis 1 | 24
Steatohepatitis 1 | 44
Subclinical abnormal liver function tests 1 | 81
Tachycardia 1 | 43
Transaminases increased 1 | 81
Tropical sprue 1 | 5
Tyrosinemia 1 | 10
Vomiting 1 | 116
Wilson disease 1 | 16
drug-induced hepatitis 1 | 44

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192

Target Family

Enzyme 6 | 4,145
Kinase 1 | 634

GO Process

fructose 1,6-bisphosphate meta... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fructose-1,6-bisphosphatase 1 FBP1 Tchem Enzyme -2.06824 111.8 202
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240
Fructose-2,6-bisphosphatase TIGAR TIGAR Tbio Enzyme -1.74902 58.9 273
Fructose-bisphosphate aldolase A ALDOA Tbio Enzyme -2.11333 124.4 435
Fructose-bisphosphate aldolase C ALDOC Tbio Enzyme -1.67315 44.0 268
Fructose-1,6-bisphosphatase isozyme 2 FBP2 Tbio Enzyme -2.05630 110.1 144
Fructose-bisphosphate aldolase B ALDOB Tbio Enzyme -2.65232 442.1 260