Development Level

Tbio 9 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 9 | 11,493
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 6 | 7,950
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
glioblastoma 4 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
Bilateral fifth finger clinodactyly 3 | 110
Cancer 3 | 2,499
Congenital hypoplasia of penis 3 | 176
Congenital hypoplasia of radius 3 | 23
Craniofacial Abnormalities 3 | 151
Curvature of little finger 3 | 110
Holt-Oram syndrome 3 | 12
Liver cancer 3 | 604
Radial ray hypoplasia 3 | 23
Short stature 3 | 531
Short ulnae 3 | 24
Strabismus 3 | 270
ULNAR HYPOPLASIA 3 | 24
Ventricular Septal Defects 3 | 119
atypical teratoid / rhabdoid tumor 3 | 5,112
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
Accessory rib 2 | 10
Acheiropody 2 | 4
Acquired metabolic disease 2 | 336
Arthritis, Rheumatoid 2 | 174
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Bilateral single transverse palmar creases 2 | 34
Blepharoptosis 2 | 231
Bowed and upward slanting eyebrows 2 | 41
Bushy eyebrows 2 | 49
Concave bridge of nose 2 | 195
Congenital heart disease 2 | 93
Congenital hypoplasia of femur 2 | 8
Cryptorchidism 2 | 296
Delayed bone age 2 | 136
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dull intelligence 2 | 645
Fibular hypoplasia 2 | 9
Flatfoot 2 | 73
Hernia, Inguinal 2 | 89
Hypodontia 2 | 81
Hypoplasia of nipple 2 | 16
Hypoplastic feet 2 | 66
Intellectual disability 2 | 1,016
Joint stiffness 2 | 84
Late tooth eruption 2 | 61
Low intelligence 2 | 645
Low set ears 2 | 181
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Micromelia 2 | 58
Obesity 2 | 678
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Pyloric Stenosis 2 | 47
Radial aplasia/hypoplasia 2 | 29
Sensorineural Hearing Loss (disorder) 2 | 284
Short first metacarpals 2 | 11
Short middle phalanx of the 5th finger 2 | 13
Short tibia 2 | 9
Short upper arms 2 | 16
Sick sinus syndrome 2 | 15
Simple syndactyly of toes, first web space 2 | 23
Single transverse palmar crease 2 | 29
Small head 2 | 374
Speech Disorders 2 | 58
Thick, flared eyebrows 2 | 41
Thin lips 2 | 49
Thumb aplasia 2 | 16
Ulnar polydactyly of fingers 2 | 47
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
ulnar-mammary syndrome 2 | 8
Chromosome 18q deletion syndrome 1 | 10
Ductus Arteriosus, Patent 1 | 6
First degree atrioventricular block 1 | 5
Proximal symphalangism 1 | 7
Spondylolysis 1 | 14

Tissue

Endocrine System 10 | 18,159
Male tissues 10 | 17,142
Urinary Tract 10 | 16,678
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Skin and soft tissues 9 | 17,230
Blood and immune system 8 | 16,909
Liver and Pancreas 8 | 16,750
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Transcription Factor 6 | 1,400
Non-IDG 4 | 12,091

GO Process

forelimb morphogenesis 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.42253 255.6 328
E3 ubiquitin-protein ligase RNF165 RNF165 Tdark Non-IDG 0.33 0.39 113
Sal-like protein 3 SALL3 Tbio Transcription Factor -0.98197 10.1 22
Zinc finger and BTB domain-containing protein 16 ZBTB16 Tbio Transcription Factor -2.31797 210.0 275
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
Homeobox protein Hox-D10 HOXD10 Tbio Transcription Factor -1.78620 51.3 214
Formin-1 FMN1 Tbio Non-IDG -2.80166 584.6 58
Transcription factor AP-2-beta TFAP2B Tbio Transcription Factor -1.74089 52.9 225
T-box transcription factor TBX5 TBX5 Tbio Transcription Factor -2.38269 244.4 198
Growth/differentiation factor 5 GDF5 Tbio Non-IDG -2.57648 401.8 301