Development Level

Tbio 28 | 11,445
Tchem 10 | 1,598
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
enlarged heart 3 | 210
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased lean body mass 2 | 172
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal duodenum morphology 1 | 4
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
premature death 1 | 5
prolonged QRS complex duration 1 | 8
short tibia 1 | 97

Disease

Carcinoma 37 | 11,493
ovarian cancer 28 | 8,520
Cancer 25 | 2,499
psoriasis 25 | 6,694
medulloblastoma, large-cell 23 | 6,241
glioblastoma 22 | 5,792
atypical teratoid / rhabdoid tumor 21 | 5,112
osteosarcoma 21 | 7,950
lung cancer 20 | 4,740
Kidney cancer 19 | 2,613
ependymoma 18 | 4,679
group 3 medulloblastoma 18 | 4,104
malignant mesothelioma 17 | 3,232
Breast cancer 14 | 3,578
pancreatic cancer 13 | 2,398
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
astrocytic glioma 12 | 2,597
lung adenocarcinoma 12 | 2,716
non-small cell lung cancer 12 | 2,890
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
Schizophrenia 11 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pediatric high grade glioma 10 | 1,064
Astrocytoma, Pilocytic 9 | 3,081
Epilepsy 9 | 792
Pick disease 9 | 1,894
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung carcinoma 9 | 2,843
Dull intelligence 8 | 645
Intellectual disability 8 | 1,016
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Muscle hypotonia 8 | 571
Poor school performance 8 | 645
Seizures 8 | 596
adult high grade glioma 8 | 3,801
subependymal giant cell astrocytoma 8 | 2,287
ulcerative colitis 8 | 1,819
Bipolar Disorder 7 | 666
Breast Neoplasms 7 | 445
Liver cancer 7 | 604
Mammary Neoplasms 7 | 425
Short stature 7 | 531
group 4 medulloblastoma 7 | 1,855
Craniofacial Abnormalities 6 | 151
Holoprosencephaly 6 | 56
Parkinson's disease 6 | 392
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
invasive ductal carcinoma 6 | 2,951
Adenoma 5 | 167
Cryptorchidism 5 | 296
Small head 5 | 374
Status Epilepticus 5 | 98
Strabismus 5 | 270
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
Abnormally small eyeball 4 | 97
Acromegaly 4 | 51
Adenoid Cystic Carcinoma 4 | 99
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Carcinoid syndrome 4 | 5
Carcinoma, Adenoid Cystic 4 | 99
Colorectal Neoplasms 4 | 243
Decreased size of eyeball 4 | 97
Depressed nasal ridge 4 | 51
Diarrhea from Pancreatic VIPoma 4 | 5
Gait abnormality 4 | 135
Liver Cirrhosis, Experimental 4 | 769
Major Depressive Disorder 4 | 301
Malar flattening 4 | 129
Microphthalmos 4 | 100
Neurodegenerative disease 4 | 414
Neuroendocrine Tumors 4 | 11
Obesity 4 | 678
Orbital separation excessive 4 | 244
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Pituitary adenoma 4 | 38
Rheumatoid arthritis 4 | 1,191
Stomach Neoplasms 4 | 300
Unipolar Depression 4 | 250
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010

Tissue

Nervous System 44 | 16,725
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 41 | 17,400
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Blood and immune system 40 | 16,909
Liver and Pancreas 40 | 16,750
Respiratory system 39 | 16,393
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 17 | 12,091
Transcription Factor 9 | 1,400
Enzyme 7 | 4,145
GPCR 5 | 408
Kinase 4 | 634
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

GO Process

forebrain development 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.60757 39.5 23
Serine/threonine-protein kinase DCLK1 DCLK1 Tchem Kinase -2.08177 129.5 320
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Draxin DRAXIN Tbio Non-IDG -1.20890 16.8 111
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 NDST1 Tbio Enzyme -1.91878 84.7 146
Lysine-specific demethylase 2B KDM2B Tchem Epigenetic -1.56328 41.7 248
Twisted gastrulation protein homolog 1 TWSG1 Tbio Non-IDG -2.47209 291.9 79