Development Level

Tbio 14 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 2 | 298
decreased circulating serum al... 2 | 82
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
hyperactivity 1 | 148
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating free fat... 1 | 20
increased circulating total pr... 1 | 28
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
increased mature B cell number 1 | 1
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased vertical activity 1 | 24
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 13 | 11,493
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
non-small cell lung cancer 8 | 2,890
ovarian cancer 8 | 8,520
ependymoma 7 | 4,679
Aarskog syndrome 6 | 12
Breast cancer 6 | 3,578
glioblastoma 6 | 5,792
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
ductal carcinoma in situ 5 | 1,745
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
breast carcinoma 4 | 1,638
gastric cancer 4 | 459
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
Cancer 3 | 2,499
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
ulcerative colitis 3 | 1,819
Animal Mammary Neoplasms 2 | 136
Autosomal recessive predisposition 2 | 1,442
Brachydactyly 2 | 156
Common variable immunodeficiency 2 | 101
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Urogenital Abnormalities 2 | 9
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
ANONYCHIA 1 | 20
Aplasia Cutis Congenita 1 | 14
Atrophic scar 1 | 18
Attention Deficit Disorder with Hyperactivity 1 | 21
Axillary pterygia 1 | 6
Broad feet 1 | 19
Congenital scar 1 | 13
Decreased projection of maxilla 1 | 66
Defective enamel matrix 1 | 35
Deficiency of upper jaw bones 1 | 66
Delayed Puberty 1 | 97
Dental Enamel Hypoplasia 1 | 43
Diabetes Mellitus, Experimental 1 | 108
Dysplasia of tooth enamel 1 | 35
Epidermolysis bullosa 1 | 21
Esophageal atresia 1 | 43
Everted lower lip vermilion 1 | 54
Fragile skin 1 | 18
Griscelli syndrome 1 | 24
Growth Disorders 1 | 35
Hypodontia 1 | 81
Hypoplasia of the maxilla 1 | 66
Hypoplastic feet 1 | 66
Hypotrophic maxilla 1 | 66
Junctional split 1 | 6
Maxillary retrognathia 1 | 66
Milium Cyst 1 | 16
Neurofibromatosis 1 | 40
ODONTOID HYPOPLASIA 1 | 16
Oral mucosal blistering 1 | 10
Protruding lower lip 1 | 54
Retrusion of upper jaw bones 1 | 66
Round face 1 | 45
Round, full face 1 | 45
Scoliosis 1 | 44
Syndactyly of fingers 1 | 48
Thin dental enamel 1 | 35
Urethral Stricture 1 | 18
X- linked recessive 1 | 110

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Skin and soft tissues 17 | 17,230
Cardiovascular System 16 | 15,192
Respiratory system 16 | 16,393
Urinary Tract 16 | 16,678

Target Family

Non-IDG 13 | 12,091
Enzyme 3 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

filopodium assembly 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SH3 domain-binding protein 1 SH3BP1 Tbio Non-IDG 0.00000 168
Neurabin-2 PPP1R9B Tdark Non-IDG 0.00000 0
FYVE, RhoGEF and PH domain-containing protein 1 FGD1 Tbio Non-IDG -2.02545 109.7 42
SLIT-ROBO Rho GTPase-activating protein 2 SRGAP2 Tbio Enzyme -1.09985 24.7 0
FYVE, RhoGEF and PH domain-containing protein 3 FGD3 Tbio Non-IDG -0.92940 8.84 116
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
FYVE, RhoGEF and PH domain-containing protein 2 FGD2 Tbio Non-IDG 0.00000 51
Protein tweety homolog 1 TTYH1 Tbio Ion Channel -0.94799 0.00000 131
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.40554 28.0 126
Dynamin-3 DNM3 Tbio Non-IDG -1.43916 22.6 146