Development Level

Tbio 5 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

increased circulating triglyce... 1 | 42
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499

Disease

atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Atopic dermatitis 3 | 952
Carcinoma 3 | 11,493
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Autosomal dominant cerebellar ataxia 2 | 33
Breast cancer 2 | 3,578
Ichthyosis 2 | 56
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
gastric cancer 2 | 459
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
Abnormal color vision 1 | 31
Abnormal visual evoked potential 1 | 26
Abnormality of the choroid 1 | 7
Adrenoleukodystrophy 1 | 29
Age related macular degeneration 1 | 72
Alzheimer's disease 1 | 658
Aplasia/Hypoplasia of the macula 1 | 8
Attention deficit hyperactivity disorder 1 | 278
Axenfeld-Rieger syndrome 1 | 14
Choroid Diseases 1 | 7
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Decreased tendon reflex 1 | 122
Difficulties with night vision 1 | 87
Dry skin 1 | 75
Duchenne muscular dystrophy 1 | 601
Dysarthria 1 | 192
Dysdiadochokinesis 1 | 25
Epilepsy 1 | 792
Erythrokeratodermia variabilis 1 | 10
Fatty liver disease 1 | 103
Fundus dystrophy 1 | 83
Gastric antral vascular ectasia 1 | 10
Glaucoma 1 | 239
Heart failure 1 | 162
Hypohidrosis 1 | 34
Infertility, Male 1 | 46
Liver Cirrhosis, Experimental 1 | 769
Macular degeneration 1 | 65
Macule 1 | 19
Male infertility 1 | 206
Mitochondrial encephalomyopathy 1 | 15
Night Blindness 1 | 101
Open-angle glaucoma 1 | 27
Papule 1 | 43
Peroxisomal disease 1 | 22
Progressive cerebellar ataxia 1 | 13
Reduced visual acuity 1 | 63
Retinal Degeneration 1 | 106
Retinitis pigmentosa 25 1 | 9
Simpson-Golabi-Behmel syndrome 1 | 19
Spastic Quadriplegia 1 | 42
Spinocerebellar Ataxias 1 | 34
Stargardt disease 1 | 6
Umbilical hernia 1 | 93
Urticaria 1 | 67
Waldenstrons macroglobulinemia 1 | 765
Xerosis 1 | 75
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic rhinosinusitis 1 | 512
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
hepatocellular carcinoma 1 | 547
juvenile dermatomyositis 1 | 1,187
non diabetic and post-ischemic heart failure 1 | 200
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192

Target Family

Non-IDG 7 | 12,091

GO Process

fatty acid elongation, saturat... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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