Development Level

Tbio 53 | 11,445
Tchem 9 | 1,598
Tdark 5 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
decreased circulating choleste... 2 | 93
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased vertical activity 2 | 208
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal glucose homeostasis 1 | 4
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
short tibia 1 | 97
small adrenal glands 1 | 16
small heart 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 46 | 11,493
ovarian cancer 42 | 8,520
osteosarcoma 36 | 7,950
medulloblastoma, large-cell 35 | 6,241
psoriasis 32 | 6,694
atypical teratoid / rhabdoid tumor 27 | 5,112
lung cancer 27 | 4,740
glioblastoma 25 | 5,792
Breast cancer 24 | 3,578
ependymoma 24 | 4,679
Obesity 23 | 678
malignant mesothelioma 21 | 3,232
Cancer 20 | 2,499
adult high grade glioma 20 | 3,801
invasive ductal carcinoma 19 | 2,951
pituitary cancer 18 | 1,972
diabetes mellitus 17 | 1,728
group 3 medulloblastoma 17 | 4,104
Astrocytoma, Pilocytic 16 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung carcinoma 16 | 2,843
non-small cell lung cancer 16 | 2,890
ulcerative colitis 16 | 1,819
Rheumatoid arthritis 15 | 1,191
breast carcinoma 15 | 1,638
ductal carcinoma in situ 15 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung adenocarcinoma 14 | 2,716
Autosomal recessive predisposition 13 | 1,442
Kidney cancer 13 | 2,613
interstitial cystitis 13 | 2,312
oligodendroglioma 13 | 2,850
pancreatic cancer 13 | 2,398
Pick disease 12 | 1,894
astrocytic glioma 12 | 2,597
tuberculosis 12 | 2,010
cystic fibrosis 11 | 1,696
subependymal giant cell astrocytoma 11 | 2,287
Intellectual disability 10 | 1,016
Liver Cirrhosis, Experimental 10 | 769
Schizophrenia 10 | 1,160
acute quadriplegic myopathy 10 | 1,158
adrenocortical carcinoma 10 | 1,428
astrocytoma 10 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Short stature 9 | 531
gastric cancer 9 | 459
group 4 medulloblastoma 9 | 1,855
Bipolar Disorder 8 | 666
Hypertensive disease 8 | 292
juvenile dermatomyositis 8 | 1,187
pancreatic carcinoma 8 | 562
primitive neuroectodermal tumor 8 | 3,035
Bardet-Biedl syndrome 7 | 51
Bardet-Biedl syndrome 1 7 | 22
Congenital hypoplasia of penis 7 | 176
Epilepsy 7 | 792
Multicystic Dysplastic Kidney 7 | 52
Nystagmus 7 | 317
Polydactyly 7 | 107
Retinitis Pigmentosa 7 | 226
colon cancer 7 | 1,478
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
non primary Sjogren syndrome sicca 7 | 891
primary pancreatic ductal adenocarcinoma 7 | 1,109
Atopic dermatitis 6 | 952
Congenital hypoplasia of ovary 6 | 30
Delayed speech and language development 6 | 112
Electroretinogram abnormal 6 | 95
Hyperinsulinism 6 | 133
Hypogonadism 6 | 173
Hypoplastic ovary 6 | 30
Increase in blood pressure 6 | 119
Insulin Resistance 6 | 72
Language Delay 6 | 112
Lipodystrophy 6 | 40
Major Depressive Disorder 6 | 301
Multiple myeloma 6 | 1,332
Speech Delay 6 | 112
Speech impairment 6 | 112
Ulnar polydactyly of fingers 6 | 47
active Crohn's disease 6 | 922
chronic rhinosinusitis 6 | 512
hepatocellular carcinoma 6 | 547
medulloblastoma 6 | 720
nasopharyngeal carcinoma 6 | 1,058
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Myocardial Ischemia 5 | 169
Waldenstrons macroglobulinemia 5 | 765
acute myeloid leukemia 5 | 783
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 559

Tissue

Digestive Tract 68 | 17,369
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Skin and soft tissues 68 | 17,230
Blood and immune system 67 | 16,909
Male tissues 66 | 17,142
Nervous System 66 | 16,725
Respiratory system 66 | 16,393
Cardiovascular System 65 | 15,192
Urinary Tract 65 | 16,678
Liver and Pancreas 64 | 16,750

Target Family

Non-IDG 32 | 12,091
Transcription Factor 16 | 1,400
Enzyme 10 | 4,145
GPCR 3 | 408
Kinase 3 | 634
Nuclear Receptor 3 | 48
Epigenetic 1 | 242

GO Process

fat cell differentiation 68 | 68
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Nucleolar complex protein 3 homolog NOC3L Tbio Non-IDG -1.13056 15.6 168
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Transmembrane protein 120B TMEM120B Tdark Non-IDG 0.41 0.30 20
Oxysterol-binding protein-related protein 11 OSBPL11 Tbio Non-IDG -0.39260 3.03 185
Transmembrane protein 120A TMEM120A Tdark Non-IDG 0.00000 16