Development Level

Tbio 24 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal heart morphology 3 | 162
enlarged heart 3 | 210
decreased lymphocyte cell numb... 2 | 83
prenatal lethality prior to he... 2 | 87
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal response to new envir... 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cleft palate 1 | 8
cyanosis 1 | 7
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499
scaly skin 1 | 4
small superior vagus ganglion 1 | 74

Disease

Carcinoma 25 | 11,493
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 18 | 6,241
psoriasis 18 | 6,694
pancreatic cancer 16 | 2,398
Cancer 15 | 2,499
lung cancer 15 | 4,740
glioblastoma 14 | 5,792
osteosarcoma 13 | 7,950
Breast cancer 12 | 3,578
Hypoplastic mandible condyle 12 | 275
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
non-small cell lung cancer 12 | 2,890
Cleft Palate 11 | 271
atypical teratoid / rhabdoid tumor 11 | 5,112
group 3 medulloblastoma 11 | 4,104
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
Short stature 10 | 531
adrenocortical carcinoma 10 | 1,428
malignant mesothelioma 10 | 3,232
primary pancreatic ductal adenocarcinoma 10 | 1,109
adult high grade glioma 9 | 3,801
breast carcinoma 9 | 1,638
ependymoma 9 | 4,679
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Astrocytoma, Pilocytic 8 | 3,081
Craniofacial Abnormalities 8 | 151
Kidney cancer 8 | 2,613
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
lung carcinoma 8 | 2,843
ulcerative colitis 8 | 1,819
Acquired scoliosis 7 | 281
Autosomal recessive predisposition 7 | 1,442
Cleft Lip 7 | 141
Curvature of spine 7 | 282
Orbital separation excessive 7 | 244
Osteoporosis 7 | 363
Pick disease 7 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
Blepharoptosis 6 | 231
Byzanthine arch palate 6 | 194
Duchenne muscular dystrophy 6 | 601
Exophthalmos 6 | 112
Intellectual disability 6 | 1,016
Prominent eyes 6 | 96
Prominent globes 6 | 96
Protruding eyes 6 | 96
Rheumatoid arthritis 6 | 1,191
Small head 6 | 374
astrocytic glioma 6 | 2,597
Broad flat nasal bridge 5 | 236
Congenital Epicanthus 5 | 177
Cryptorchidism 5 | 296
Decreased projection of maxilla 5 | 66
Decreased projection of midface 5 | 105
Deficiency of upper jaw bones 5 | 66
Downward slant of palpebral fissure 5 | 158
Dull intelligence 5 | 645
Epilepsy 5 | 792
Feeding difficulties in infancy 5 | 175
Hernia, Inguinal 5 | 89
Hypoplasia of the maxilla 5 | 66
Hypotrophic maxilla 5 | 66
Hypotrophic midface 5 | 105
Kyphoscoliosis deformity of spine 5 | 60
Liver Cirrhosis, Experimental 5 | 769
Long philtrum 5 | 137
Low intelligence 5 | 645
Low-set, posteriorly rotated ears 5 | 110
Maxillary retrognathia 5 | 66
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Midface retrusion 5 | 105
Muscle hypotonia 5 | 571
Nasal bridge wide 5 | 236
Pectus excavatum 5 | 100
Poor school performance 5 | 645
Retrusion of upper jaw bones 5 | 66
Seizures 5 | 596
Small midface 5 | 105
Strabismus 5 | 270
Uranostaphyloschisis 5 | 167
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
gastric carcinoma 5 | 807
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
primitive neuroectodermal tumor 5 | 3,035
spina bifida 5 | 1,074
Multiple myeloma 4 | 1,332
acute myeloid leukemia 4 | 783

Tissue

Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Nervous System 31 | 16,725
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 8 | 1,400
Enzyme 7 | 4,145
Kinase 1 | 634

GO Process

face morphogenesis 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157
Zinc finger protein 84 ZNF84 Tdark Transcription Factor -0.57958 3.24 27
Cysteine-rich secretory protein LCCL domain-containing 2 CRISPLD2 Tbio Non-IDG -1.13460 15.4 88
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.84150 362.9 46
Myosin-3 MYH3 Tbio Non-IDG -1.74714 48.2 51
Ankyrin repeat domain-containing protein 11 ANKRD11 Tbio Non-IDG -2.55588 339.7 93
Claudin-5 CLDN5 Tbio Non-IDG -2.58968 349.4 300