Development Level

Tbio 20 | 11,651
Tchem 9 | 1,388
Tclin 2 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
edema 1 | 59
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
increased basophil cell number 1 | 7
increased body length 1 | 32
increased body weight 1 | 25
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
pale liver 1 | 6
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Cancer 19 | 2,499
ovarian cancer 18 | 8,520
psoriasis 18 | 6,694
Carcinoma 17 | 11,493
osteosarcoma 14 | 7,950
lung cancer 13 | 4,740
medulloblastoma, large-cell 13 | 6,241
glioblastoma 11 | 5,792
malignant mesothelioma 10 | 3,232
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
oligodendroglioma 9 | 2,850
Breast cancer 8 | 3,578
pancreatic cancer 8 | 2,398
tuberculosis 8 | 2,010
Prostatic Neoplasms 7 | 495
Schizophrenia 7 | 1,160
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
Astrocytoma, Pilocytic 6 | 3,081
Hypersensitivity reaction type II disease 6 | 253
Multiple Sclerosis 6 | 540
Rheumatoid arthritis 6 | 1,191
astrocytic glioma 6 | 2,597
dermatomyositis 6 | 966
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer's disease 5 | 658
Arthritis 5 | 290
Autosomal recessive predisposition 5 | 1,442
Diabetes Mellitus, Experimental 5 | 108
Fever 5 | 138
Intellectual disability 5 | 1,016
Lung Neoplasms 5 | 232
diabetes mellitus 5 | 1,728
gastric carcinoma 5 | 807
lung adenocarcinoma 5 | 2,716
Adenocarcinoma 4 | 122
Colonic Neoplasms 4 | 142
Depressive disorder 4 | 409
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Fatigue 4 | 182
Kidney cancer 4 | 2,613
Leukemia, Myelocytic, Acute 4 | 120
Leukemia, Myeloid, Acute 4 | 105
Liver disease 4 | 237
Myocardial Infarction 4 | 151
Nerve Degeneration 4 | 121
Polycystic ovary syndrome 4 | 360
Splenomegaly 4 | 190
Vasculitis 4 | 80
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
esophageal adenocarcinoma 4 | 737
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Alzheimer Disease 3 | 83
Asthma 3 | 385
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Brain Ischemia 3 | 110
Cardiomyopathies 3 | 110
Cardiomyopathy, Dilated 3 | 83
Diarrhea 3 | 253
Endometriosis 3 | 540
Glaucoma 3 | 239
Heart failure 3 | 162
Infantile onset 3 | 238
Inflammatory bowel disease 3 | 151
Liver Failure, Acute 3 | 29
Lung disease 3 | 142
Melanoma 3 | 711
Mental Depression 3 | 333
Mesothelioma, Malignant 3 | 105
Multiple myeloma 3 | 1,332
Necrosis 3 | 53
Osteoarthritis 3 | 184
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Parkinson's disease 3 | 392
Sensorineural Hearing Loss (disorder) 3 | 284
Urticaria 3 | 67
Vascular disease 3 | 319
adult high grade glioma 3 | 3,801
cutaneous lupus erythematosus 3 | 1,057
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634

GO Process

extrinsic apoptotic signaling ... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-binding death effector domain-containing protein 2 DEDD2 Tbio Non-IDG -0.55115 3.37 164
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Death-associated protein kinase 1 DAPK1 Tchem Kinase -2.34153 226.1 276
CASP8-associated protein 2 CASP8AP2 Tbio Non-IDG 0.00000 0
Tumor necrosis factor ligand superfamily member 6 FASLG Tbio Non-IDG -3.53551 3585.2 953
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.51919 316.4 758
Apoptosis regulator BAX BAX Tchem Non-IDG -2.57834 248.4 1395
Apoptosis regulator Bcl-2 BCL2 Tclin Non-IDG -2.20455 130.6 2273
Tumor necrosis factor receptor superfamily member 10B TNFRSF10B Tbio Non-IDG -3.15963 1514.8 849