Development Level

Tchem 15 | 1,598
Tbio 14 | 11,445
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased total body fat amoun... 3 | 207
preweaning lethality, complete... 3 | 979
decreased lean body mass 2 | 135
hypoactivity 2 | 132
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased erythrocyte cell num... 1 | 62
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased body weight 1 | 25
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Cancer 25 | 2,499
ovarian cancer 22 | 8,520
psoriasis 21 | 6,694
glioblastoma 18 | 5,792
medulloblastoma, large-cell 18 | 6,241
Carcinoma 17 | 11,493
osteosarcoma 15 | 7,950
Schizophrenia 13 | 1,160
ependymoma 13 | 4,679
diabetes mellitus 11 | 1,728
lung cancer 11 | 4,740
tuberculosis 11 | 2,010
Vascular disease 10 | 319
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
Alzheimer's disease 9 | 658
Astrocytoma, Pilocytic 9 | 3,081
Breast cancer 9 | 3,578
atypical teratoid / rhabdoid tumor 9 | 5,112
lung carcinoma 9 | 2,843
Rheumatoid arthritis 8 | 1,191
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
ulcerative colitis 8 | 1,819
Bipolar Disorder 7 | 666
Diabetes Mellitus, Experimental 7 | 108
Fever 7 | 138
Prostatic Neoplasms 7 | 495
cutaneous lupus erythematosus 7 | 1,057
group 4 medulloblastoma 7 | 1,855
invasive ductal carcinoma 7 | 2,951
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Arthritis 6 | 290
Asthma 6 | 385
Hypersensitivity reaction type II disease 6 | 253
Inflammatory bowel disease 6 | 151
Kidney disease 6 | 430
Lung Neoplasms 6 | 232
Myocardial Infarction 6 | 151
Obesity 6 | 678
gastric cancer 6 | 459
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
nasopharyngeal carcinoma 6 | 1,058
primitive neuroectodermal tumor 6 | 3,035
spina bifida 6 | 1,074
Alzheimer Disease 5 | 83
Breast Neoplasms 5 | 445
Cerebral Hemorrhage 5 | 42
Chemical and Drug Induced Liver Injury 5 | 195
Depressive disorder 5 | 409
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Kidney cancer 5 | 2,613
Lung disease 5 | 142
Mammary Neoplasms 5 | 425
Multiple Sclerosis 5 | 540
Multiple myeloma 5 | 1,332
Parkinson's disease 5 | 392
Toxic encephalopathy 5 | 141
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
primary pancreatic ductal adenocarcinoma 5 | 1,109
sarcoidosis 5 | 370
Anemia 4 | 365
Autistic Disorder 4 | 364
Brain Injuries 4 | 65
Brain Ischemia 4 | 110
Cardiomyopathies 4 | 110
Colonic Neoplasms 4 | 142
Dermatitis 4 | 157
Dermatitis, Allergic Contact 4 | 67
Esophageal Neoplasms 4 | 69
Heart disease 4 | 306
Hypertension 4 | 396
Influenza 4 | 142
Leishmaniasis 4 | 47
Liver disease 4 | 237
Major Depressive Disorder 4 | 301
Mental Depression 4 | 333
Myopathy 4 | 185
Neoplasm Metastasis 4 | 168
Nerve Degeneration 4 | 121
Neuropathy 4 | 261
Reperfusion Injury 4 | 86
aldosterone-producing adenoma 4 | 665
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Female tissues 33 | 17,400
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Endocrine System 32 | 18,159
Liver and Pancreas 32 | 16,750
Urinary Tract 32 | 16,678
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Transcription Factor 1 | 1,400

GO Process

extrinsic apoptotic signaling ... 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
MAP kinase-interacting serine/threonine-protein kinase 2 MKNK2 Tchem Kinase -1.32729 19.5 234
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.64193 42.6 207
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Bcl-2 homologous antagonist/killer BAK1 Tbio Non-IDG -2.29199 175.9 554