Development Level

Tbio 25 | 11,445
Tchem 10 | 1,598
Tclin 6 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
abnormal coat- hair morphology 2 | 19
abnormal embryo size 2 | 220
abnormal midbrain development 2 | 20
abnormal neural tube closure 2 | 46
cataract 2 | 92
embryonic lethality prior to o... 2 | 239
increased prepulse inhibition 2 | 32
small superior vagus ganglion 2 | 74
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased circulating glycerol... 1 | 16
decreased heart left ventricle... 1 | 28
decreased lymphocyte cell numb... 1 | 83
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased erythrocyte cell num... 1 | 39
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
short tibia 1 | 97
small adrenal glands 1 | 16
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Cancer 31 | 2,499
ovarian cancer 26 | 8,520
osteosarcoma 24 | 7,950
psoriasis 23 | 6,694
Carcinoma 22 | 11,493
glioblastoma 19 | 5,792
lung cancer 17 | 4,740
atypical teratoid / rhabdoid tumor 16 | 5,112
Astrocytoma, Pilocytic 15 | 3,081
medulloblastoma, large-cell 15 | 6,241
ulcerative colitis 14 | 1,819
adult high grade glioma 13 | 3,801
interstitial cystitis 13 | 2,312
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
subependymal giant cell astrocytoma 12 | 2,287
tuberculosis 12 | 2,010
cutaneous lupus erythematosus 11 | 1,057
ependymoma 11 | 4,679
Breast cancer 10 | 3,578
Rheumatoid arthritis 10 | 1,191
Arthritis 9 | 290
Liver Cirrhosis, Experimental 9 | 769
Liver disease 9 | 237
Multiple Sclerosis 9 | 540
Schizophrenia 9 | 1,160
Vascular disease 9 | 319
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
Asthma 8 | 385
Breast Neoplasms 8 | 445
Hypersensitivity reaction type II disease 8 | 253
Mammary Neoplasms 8 | 425
Pneumonia 8 | 174
group 4 medulloblastoma 8 | 1,855
lung adenocarcinoma 8 | 2,716
primary Sjogren syndrome 8 | 735
Liver Cirrhosis 7 | 181
Prostatic Neoplasms 7 | 495
Splenomegaly 7 | 190
Vasculitis 7 | 80
astrocytic glioma 7 | 2,597
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 4,104
non-small cell lung cancer 7 | 2,890
Bipolar Disorder 6 | 666
Fever 6 | 138
Inflammatory bowel disease 6 | 151
Kidney cancer 6 | 2,613
Liver Failure, Acute 6 | 29
Lung Neoplasms 6 | 232
Lung disease 6 | 142
colon cancer 6 | 1,478
gastric carcinoma 6 | 807
Adenocarcinoma 5 | 122
Atherosclerosis 5 | 291
Coronary artery disease 5 | 268
Crohn's disease 5 | 321
Depressive disorder 5 | 409
Diabetes Mellitus, Experimental 5 | 108
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Hepatitis C 5 | 94
Hepatomegaly 5 | 285
Hypertensive disease 5 | 292
Kidney disease 5 | 430
Mental Depression 5 | 333
Myocardial Infarction 5 | 151
Pick disease 5 | 1,894
Stomach Neoplasms 5 | 300
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
nasopharyngeal carcinoma 5 | 1,058
non-small cell lung carcinoma 5 | 317
pancreatic cancer 5 | 2,398
Anemia 4 | 365
Arthritis, Rheumatoid 4 | 174
Colonic Neoplasms 4 | 142
Dermatitis 4 | 157
Disease Models, Animal 4 | 155
Endometriosis 4 | 540
Glaucoma 4 | 239
Hepatitis B 4 | 108
Hypereosinophilic syndrome 4 | 71
Hypersensitivity 4 | 63
Liver carcinoma 4 | 240
Liver neoplasms 4 | 130
Major Depressive Disorder 4 | 301
Melanoma 4 | 711
Neurodegenerative disease 4 | 414
Polycystic ovary syndrome 4 | 360
Urticaria 4 | 67
aldosterone-producing adenoma 4 | 665
hepatocellular carcinoma 4 | 547
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 39 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 6 | 4,145
Kinase 5 | 634
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

GO Process

extrinsic apoptotic signaling ... 41 | 41
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
Sphingosine-1-phosphate phosphatase 1 SGPP1 Tbio Enzyme -0.90666 6.54 76
Tumor necrosis factor receptor superfamily member 12A TNFRSF12A Tbio Non-IDG -2.13589 160.9 382
Apoptosis regulatory protein Siva SIVA1 Tbio Non-IDG -1.84195 71.7 191
Activin receptor type-1B ACVR1B Tchem Kinase -2.00550 91.2 418
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565