Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal optic disc morphology 1 | 10
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
enlarged heart 1 | 210
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Carcinoma 3 | 11,493
Kidney cancer 3 | 2,613
Broad flat nasal bridge 2 | 236
Corneal diameter decreased 2 | 47
Endometrial cancer 2 | 311
Microcornea 2 | 47
Nasal bridge wide 2 | 236
Strabismus 2 | 270
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
medulloblastoma, large-cell 2 | 6,241
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
sonic hedgehog group medulloblastoma 2 | 467
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Abnormality of the abdominal wall 1 | 10
Abnormality of the conjunctiva 1 | 2
Abnormally prominent line of Schwalbe 1 | 2
Amenorrhea 1 | 58
Amyloidosis 1 | 67
Aniridia 1 | 25
Anterior chamber anomalies 1 | 4
Anterior segment mesenchymal dysgenesis 1 | 7
Axenfeld anomaly (disorder) 1 | 3
Axenfeld-Rieger Syndrome, Type 1 1 | 3
Axenfeld-Rieger syndrome 1 | 14
Bardet-Biedl syndrome 5 1 | 2
Brittle cornea syndrome 1 | 4
Cogan-Reese syndrome 1 | 3
Corneal abnormalities 1 | 6
Cornela disease 1 | 6
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Dental abnormalities 1 | 60
Elevated gonadotropins 1 | 15
Epicanthus inversus 1 | 3
Everted lower lip vermilion 1 | 54
Gonadoblastoma 1 | 34
Hair shaft abnormalities 1 | 30
Hypercalcemia 1 | 59
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypertrichosis 1 | 46
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Hypodontia 1 | 81
Hypoplasia of iris 1 | 10
Hypoplasia of the maxilla 1 | 66
Hypoplastic iris stoma 1 | 4
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
IRIDOGONIODYSGENESIS, TYPE 2 1 | 1
Iridogoniodysgenesis syndrome 1 | 9
Isolated somatotropin deficiency 1 | 30
Keloid 1 | 37
Laryngostenosis 1 | 10
Lymphoproliferative syndrome 1 | 58
Macroglobulinemia 1 | 18
Maxillary retrognathia 1 | 66
Midface retrusion 1 | 105
Mobius syndrome 1 | 6
Myofibrillar myopathy 5 1 | 5
Necrotizing fasciitis 1 | 10
Non-immune hydrops fetalis 1 | 11
Ovarian dysfunction 1 | 18
POEMS syndrome 1 | 6
Persistent hyperplastic primary vitreous 1 | 20
Peters anomaly 1 | 16
Pharyngitis 1 | 17
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Pituitary hypoplasia 1 | 23
Polycoria 1 | 1
Polyneuropathy 1 | 64
Premature Menopause 1 | 31
Premature ovarian failure 1 | 65
Prominent supraorbital ridges 1 | 19
Protruding lower lip 1 | 54
Pyoderma 1 | 4
RING DERMOID OF CORNEA 1 | 1
Retrusion of upper jaw bones 1 | 66
Rheumatic fever 1 | 19
Rheumatic heart disease 1 | 10
Rieger syndrome 1 | 8
Scarlet fever 1 | 8
Septooptic dysplasia 1 | 19
Small midface 1 | 105
Stomatitis 1 | 21
Stricture of anus 1 | 13
Subacute sclerosing panencephalitis 1 | 11
Tonsillitis 1 | 16
Tooth Abnormalities 1 | 69
Tooth agenesis 1 | 44
Toxic shock syndrome 1 | 28
Vitiligo 1 | 73
blepharophimosis, ptosis, and epicanthus inversus syndrome 1 | 8
hair abnormalities (non-specific) 1 | 30
menstrual periods stopped for over 6 months 1 | 13

Tissue

Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Male tissues 5 | 17,142
Skin and soft tissues 5 | 17,230
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Liver and Pancreas 4 | 16,750
Nervous System 4 | 16,725
Blood and immune system 3 | 16,909
Respiratory system 3 | 16,393
Urinary Tract 3 | 16,678

Target Family

Non-IDG 3 | 12,091
Transcription Factor 2 | 1,400

GO Process

extraocular skeletal muscle de... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Myosin-15 MYH15 Tbio Non-IDG -0.95780 9.01 40
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.81557 652.1 234
Myomesin-2 MYOM2 Tbio Non-IDG -3.36742 2270.3 100