Development Level

Tchem 38 | 1,890
Tbio 27 | 10,625
Tclin 5 | 602
Tdark 3 | 7,003

IMPC Term

embryonic lethality prior to t... 2 | 187
preweaning lethality, complete... 2 | 633
short tibia 2 | 82
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal esophagus morphology 1 | 4
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pancreas morphology 1 | 6
abnormal seminal vesicle morph... 1 | 47
abnormal skin coloration 1 | 18
abnormal skin morphology 1 | 23
abnormal thyroid gland morphol... 1 | 3
abnormal tooth morphology 1 | 24
abnormal trachea morphology 1 | 3
abnormal vibrissa morphology 1 | 17
absent lymph nodes 1 | 3
anophthalmia 1 | 20
athymia 1 | 1
brachydactyly 1 | 2
decreased body length 1 | 108
decreased circulating alkaline... 1 | 41
decreased circulating free fat... 1 | 39
decreased heart weight 1 | 44
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
enlarged spleen 1 | 26
hyperactivity 1 | 108
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52

Disease

ovarian cancer 41 | 8,484
Cancer 37 | 2,346
osteosarcoma 35 | 7,933
glioblastoma 31 | 5,572
invasive ductal carcinoma 31 | 2,950
pancreatic cancer 29 | 2,300
psoriasis 29 | 6,685
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
malignant mesothelioma 26 | 3,162
ulcerative colitis 26 | 2,087
atypical teratoid / rhabdoid tumor 25 | 4,369
lung cancer 25 | 4,466
pilocytic astrocytoma 25 | 3,086
non-small cell lung cancer 24 | 2,798
cystic fibrosis 22 | 1,665
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
lung carcinoma 22 | 2,844
Breast cancer 21 | 3,094
interstitial cystitis 21 | 2,299
lung adenocarcinoma 21 | 2,713
primary pancreatic ductal adenocarcinoma 21 | 1,271
Carcinoma 20 | 2,147
medulloblastoma, large-cell 20 | 6,234
ductal carcinoma in situ 19 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
diabetes mellitus 17 | 1,663
Arthritis 16 | 248
Duchenne muscular dystrophy 16 | 602
gastric carcinoma 16 | 832
posterior fossa group A ependymoma 16 | 1,511
Atopic dermatitis 15 | 944
pediatric high grade glioma 15 | 2,712
cutaneous lupus erythematosus 14 | 1,056
Kidney disease 13 | 396
oligodendroglioma 13 | 2,849
sonic hedgehog group medulloblastoma 13 | 1,482
Vascular disease 12 | 281
breast carcinoma 12 | 1,614
esophageal adenocarcinoma 12 | 737
Lung disease 11 | 132
acute quadriplegic myopathy 11 | 1,157
inflammatory breast cancer 11 | 404
subependymal giant cell astrocytoma 11 | 2,287
tuberculosis 11 | 1,557
Heart disease 10 | 279
Neoplasm Invasiveness 10 | 127
adult high grade glioma 10 | 2,148
astrocytic glioma 10 | 2,241
nasopharyngeal carcinoma 10 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
periodontitis 10 | 269
primitive neuroectodermal tumor 10 | 3,031
Atherosclerosis 9 | 275
Becker muscular dystrophy 9 | 187
IGA Glomerulonephritis 9 | 454
Mammary Neoplasms 9 | 410
colon cancer 9 | 1,475
juvenile dermatomyositis 9 | 1,189
Endometriosis 8 | 535
Neoplasm Metastasis 8 | 138
Periodontal disease 8 | 37
Rheumatoid Arthritis 8 | 1,160
adrenocortical carcinoma 8 | 1,427
astrocytoma 8 | 1,493
dermatomyositis 8 | 933
pituitary cancer 8 | 1,972
Degenerative disc disease 7 | 28
Glaucoma 7 | 134
Hypertension 7 | 287
Liver Cirrhosis, Experimental 7 | 108
Multiple Sclerosis 7 | 498
Spontaneous abortion 7 | 108
active Crohn's disease 7 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
ependymoma 7 | 2,514
Alzheimer's disease 6 | 644
Asthma 6 | 349
Hypersensitivity reaction type II disease 6 | 235
Liver disease 6 | 219
Mammary Neoplasms, Experimental 6 | 150
Marfan Syndrome 6 | 14
Multiple myeloma 6 | 1,327
Osteoarthritis 6 | 96
Prostatic Neoplasms 6 | 471
Pulmonary Fibrosis 6 | 66
limb girdle muscular dystrophy 2A 6 | 156
non-small cell lung carcinoma 6 | 413
primary Sjogren syndrome 6 | 789
Barrett's esophagus 5 | 183
Contact Dermatitis 5 | 80
Coronary artery disease 5 | 240
Down syndrome 5 | 548
Hypertensive disease 5 | 193
Inflammatory bowel disease 5 | 142
Stomach Neoplasms 5 | 282
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
interstitial lung disease 5 | 291
mucosa-associated lymphoid tissue lymphoma 5 | 480
nephrosclerosis 5 | 329
non diabetic and post-ischemic heart failure 5 | 200

Tissue

Digestive Tract 72 | 18,473
Endocrine System 72 | 18,512
Female tissues 72 | 18,647
Blood and immune system 71 | 17,995
Liver and Pancreas 71 | 18,136
Male tissues 71 | 17,969
Nervous System 71 | 18,561
Urinary Tract 71 | 18,444
Cardiovascular System 70 | 17,958
Respiratory system 69 | 17,484
Skin and soft tissues 69 | 18,115

Target Family

Enzyme 39 | 4,146
Non-IDG 34 | 11,971

GO Process

extracellular matrix disassemb... 73 | 73
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Plasma kallikrein KLKB1 Tclin Enzyme -2.88472 708.0 231
Tolloid-like protein 1 TLL1 Tbio Non-IDG -1.40066 23.4 60
Macrophage metalloelastase MMP12 Tchem Enzyme 0.00000 382
Bone morphogenetic protein 1 BMP1 Tchem Non-IDG -2.32178 220.1 155
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129
Fibronectin FN1 Tchem Non-IDG -3.04098 1121.3 1253
A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAMTS4 Tchem Enzyme -1.59386 46.6 337
Exocyst complex component 8 EXOC8 Tbio Non-IDG -1.17455 14.6 65
Stromelysin-3 MMP11 Tchem Non-IDG -2.68918 504.6 327