Development Level

Tbio 37 | 11,445
Tchem 33 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal skin coloration 2 | 25
embryonic lethality prior to t... 2 | 278
increased bone mineral content 2 | 108
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal esophagus morphology 1 | 5
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal thyroid gland morphol... 1 | 3
abnormal tooth morphology 1 | 24
abnormal trachea morphology 1 | 3
abnormal vibrissa morphology 1 | 25
absent lymph nodes 1 | 3
anophthalmia 1 | 33
athymia 1 | 2
brachydactyly 1 | 19
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased fasted circulating g... 1 | 76
small superior vagus ganglion 1 | 74

Disease

Carcinoma 57 | 11,493
ovarian cancer 43 | 8,520
osteosarcoma 39 | 7,950
Cancer 38 | 2,499
glioblastoma 33 | 5,792
invasive ductal carcinoma 32 | 2,951
psoriasis 32 | 6,694
pancreatic cancer 31 | 2,398
Breast cancer 30 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
Astrocytoma, Pilocytic 26 | 3,081
atypical teratoid / rhabdoid tumor 26 | 5,112
malignant mesothelioma 26 | 3,232
non-small cell lung cancer 26 | 2,890
lung cancer 25 | 4,740
cystic fibrosis 23 | 1,696
lung carcinoma 23 | 2,843
ulcerative colitis 23 | 1,819
adult high grade glioma 22 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
lung adenocarcinoma 22 | 2,716
medulloblastoma, large-cell 22 | 6,241
Kidney cancer 21 | 2,613
interstitial cystitis 21 | 2,312
ependymoma 20 | 4,679
diabetes mellitus 19 | 1,728
ductal carcinoma in situ 19 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Arthritis 17 | 290
primary pancreatic ductal adenocarcinoma 17 | 1,109
Atopic dermatitis 16 | 952
Autosomal recessive predisposition 16 | 1,442
Duchenne muscular dystrophy 16 | 601
gastric carcinoma 16 | 807
Kidney disease 14 | 430
Liver Cirrhosis, Experimental 14 | 769
cutaneous lupus erythematosus 14 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
astrocytic glioma 13 | 2,597
breast carcinoma 13 | 1,638
oligodendroglioma 13 | 2,850
Vascular disease 12 | 319
esophageal adenocarcinoma 12 | 737
periodontitis 12 | 293
tuberculosis 12 | 2,010
Heart disease 11 | 306
Hypertension 11 | 396
acute quadriplegic myopathy 11 | 1,158
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
Lung disease 10 | 142
Neoplasm Invasiveness 10 | 161
nasopharyngeal carcinoma 10 | 1,058
pituitary cancer 10 | 1,972
Atherosclerosis 9 | 291
Becker muscular dystrophy 9 | 191
Breast Neoplasms 9 | 445
Degenerative disc disease 9 | 35
Endometriosis 9 | 540
Mammary Neoplasms 9 | 425
Osteoporosis 9 | 363
Rheumatoid arthritis 9 | 1,191
adrenocortical carcinoma 9 | 1,428
colon cancer 9 | 1,478
juvenile dermatomyositis 9 | 1,187
Dental caries 8 | 164
Hypertensive disease 8 | 292
Multiple Sclerosis 8 | 540
Neoplasm Metastasis 8 | 168
Pulmonary Fibrosis 8 | 106
Schizophrenia 8 | 1,160
Short stature 8 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
dermatomyositis 8 | 966
limb girdle muscular dystrophy 2A 8 | 213
medulloblastoma 8 | 720
Abortion, Spontaneous 7 | 109
Aortic aneurysm 7 | 38
Glaucoma 7 | 239
Liver Cirrhosis 7 | 181
Liver disease 7 | 237
Obesity 7 | 678
Periodontal disease 7 | 40
Spontaneous abortion 7 | 113
active Crohn's disease 7 | 922
group 3 medulloblastoma 7 | 4,104
Alzheimer's disease 6 | 658
Anemia 6 | 365
Asthma 6 | 385
Coronary artery disease 6 | 268
Hypersensitivity reaction type II disease 6 | 253
Mammary Neoplasms, Experimental 6 | 154
Melanoma 6 | 711
Multiple myeloma 6 | 1,332
Osteoarthritis 6 | 184
Prostatic Neoplasms 6 | 495
active ulcerative colitis 6 | 764
interstitial lung disease 6 | 298
non-small cell lung carcinoma 6 | 317
posterior fossa group A ependymoma 6 | 468

Tissue

Digestive Tract 76 | 17,369
Female tissues 76 | 17,400
Endocrine System 75 | 18,159
Urinary Tract 75 | 16,678
Blood and immune system 74 | 16,909
Male tissues 74 | 17,142
Skin and soft tissues 74 | 17,230
Respiratory system 73 | 16,393
Liver and Pancreas 72 | 16,750
Nervous System 70 | 16,725
Cardiovascular System 63 | 15,192

Target Family

Enzyme 40 | 4,145
Non-IDG 37 | 12,091

GO Process

extracellular matrix disassemb... 77 | 77
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
A disintegrin and metalloproteinase with thrombospondin motifs 5 ADAMTS5 Tchem Enzyme -2.26251 168.4 371
Elastin ELN Tbio Non-IDG -3.36288 2144.5 299
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Signal peptide, CUB and EGF-like domain-containing protein 3 SCUBE3 Tbio Non-IDG -0.96784 11.8 138
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.36066 28.2 70
Neutrophil elastase ELANE Tclin Enzyme -3.61753 3958.4 411
Cathepsin S CTSS Tchem Enzyme -3.31099 1955.9 291
Opticin OPTC Tbio Non-IDG -1.45504 33.3 73