Development Level

Tbio 52 | 11,445
Tchem 8 | 1,598
Tdark 8 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased bone mineral content 3 | 108
increased lean body mass 3 | 172
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
hyperactivity 2 | 148
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
prenatal lethality 1 | 28
small testis 1 | 58

Disease

Carcinoma 45 | 11,493
ovarian cancer 41 | 8,520
medulloblastoma, large-cell 37 | 6,241
glioblastoma 36 | 5,792
atypical teratoid / rhabdoid tumor 34 | 5,112
osteosarcoma 33 | 7,950
ependymoma 28 | 4,679
Astrocytoma, Pilocytic 27 | 3,081
adult high grade glioma 27 | 3,801
psoriasis 27 | 6,694
group 3 medulloblastoma 22 | 4,104
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
primitive neuroectodermal tumor 19 | 3,035
oligodendroglioma 18 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung carcinoma 17 | 2,843
subependymal giant cell astrocytoma 17 | 2,287
lung cancer 16 | 4,740
malignant mesothelioma 15 | 3,232
pancreatic cancer 15 | 2,398
interstitial cystitis 13 | 2,312
invasive ductal carcinoma 13 | 2,951
Kidney cancer 12 | 2,613
lung adenocarcinoma 12 | 2,716
non-small cell lung cancer 12 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Pick disease 11 | 1,894
tuberculosis 11 | 2,010
diabetes mellitus 10 | 1,728
Breast cancer 9 | 3,578
Schizophrenia 9 | 1,160
group 4 medulloblastoma 9 | 1,855
active ulcerative colitis 8 | 764
cystic fibrosis 8 | 1,696
juvenile dermatomyositis 8 | 1,187
primary pancreatic ductal adenocarcinoma 8 | 1,109
acute quadriplegic myopathy 7 | 1,158
aldosterone-producing adenoma 7 | 665
pituitary cancer 7 | 1,972
Cancer 6 | 2,499
ductal carcinoma in situ 6 | 1,745
progressive supranuclear palsy 6 | 676
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
Arthritis 4 | 290
Epilepsy 4 | 792
Infantile onset 4 | 238
Multiple myeloma 4 | 1,332
Nystagmus 4 | 317
Obesity 4 | 678
Retinitis pigmentosa 24 4 | 15
Seizures 4 | 596
Small head 4 | 374
Tetanus 4 | 68
active Crohn's disease 4 | 922
gastric carcinoma 4 | 807
pancreatic carcinoma 4 | 562
sarcoidosis 4 | 370
Alzheimer's disease 3 | 658
Asthma 3 | 385
Atherosclerosis 3 | 291
Botulism 3 | 24
Breast Neoplasms 3 | 445
Chronic Lymphocytic Leukemia 3 | 262
Gaucher disease type 1 3 | 180
Griscelli syndrome 3 | 24
Human immunodeficiency virus infectious disease 3 | 138
Hypersensitivity 3 | 63
Influenza 3 | 142
Meningitis 3 | 67
Multiple Sclerosis 3 | 540
Muscle hypotonia 3 | 571
Pneumonia 3 | 174
Severe mental retardation (I.Q. 20-34) 3 | 99
Vascular disease 3 | 319
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
fibroadenoma 3 | 559
mucosa-associated lymphoid tissue lymphoma 3 | 484
posterior fossa group A ependymoma 3 | 468

Tissue

Endocrine System 69 | 18,159
Blood and immune system 68 | 16,909
Digestive Tract 68 | 17,369
Liver and Pancreas 68 | 16,750
Male tissues 68 | 17,142
Skin and soft tissues 68 | 17,230
Female tissues 67 | 17,400
Nervous System 67 | 16,725
Respiratory system 67 | 16,393
Urinary Tract 67 | 16,678
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 10 | 4,145
Kinase 4 | 634
GPCR 2 | 408
Transporter 1 | 473

GO Process

exocytosis 69 | 69
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exocyst complex component 3-like protein EXOC3L1 Tdark Non-IDG 0.10 1.30 62
Syntaxin-binding protein 5-like STXBP5L Tbio Non-IDG -0.71494 6.16 5
Serine/threonine-protein kinase BRSK2 BRSK2 Tchem Kinase -1.92813 85.3 187
Solute carrier family 17 member 9 SLC17A9 Tchem Transporter -1.56271 40.4 11
Secernin-3 SCRN3 Tbio Enzyme -1.24097 16.1 56
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26757 23.0 148
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 ARFGEF1 Tbio Non-IDG -0.85174 8.71 57
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 ARFGEF2 Tbio Non-IDG -1.15371 14.4 81
Synaptotagmin-like protein 2 SYTL2 Tbio Non-IDG -1.27949 19.5 60
[F-actin]-monooxygenase MICAL3 MICAL3 Tbio Enzyme -0.76459 5.21 20