Development Level

Tchem 17 | 1,598
Tbio 16 | 11,445
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal vitreous body morphol... 2 | 10
hyperactivity 2 | 148
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased body weight 1 | 161
decreased granulocyte number 1 | 6
decreased hematocrit 1 | 46
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased B cell number 1 | 9
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 27 | 11,493
ovarian cancer 19 | 8,520
Cancer 18 | 2,499
osteosarcoma 16 | 7,950
lung cancer 14 | 4,740
Kidney cancer 11 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
psoriasis 11 | 6,694
glioblastoma 10 | 5,792
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
medulloblastoma, large-cell 9 | 6,241
Breast cancer 8 | 3,578
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
atypical teratoid / rhabdoid tumor 6 | 5,112
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Multiple myeloma 5 | 1,332
Parkinson's disease 5 | 392
Pick disease 5 | 1,894
Splenomegaly 5 | 190
Stomach Neoplasms 5 | 300
invasive ductal carcinoma 5 | 2,951
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Breast Neoplasms 4 | 445
Hypertension 4 | 396
Intellectual disability 4 | 1,016
Mammary Neoplasms 4 | 425
Myocardial Reperfusion Injury 4 | 37
Rheumatoid arthritis 4 | 1,191
Somatic mutation 4 | 61
Toxic encephalopathy 4 | 141
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
tuberculosis 4 | 2,010
Atopic dermatitis 3 | 952
Autoimmune lymphoproliferative syndrome 3 | 11
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Squamous Cell 3 | 110
Colorectal Neoplasms 3 | 243
Edema 3 | 81
Failure to gain weight 3 | 365
Hemangioma 3 | 69
Huntington's disease 3 | 76
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Melanoma 3 | 711
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Retinal Detachment 3 | 51
Schizophrenia 3 | 1,160
Skin Neoplasms 3 | 69
Squamous cell carcinoma 3 | 129
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
non-small cell lung carcinoma 3 | 317
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Adenoma 2 | 167
Brain Ischemia 2 | 110
Dermatitis, Allergic Contact 2 | 67
Endometrial cancer 2 | 311
Heart disease 2 | 306
Hepatomegaly 2 | 285
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Lung disease 2 | 142
Myopathy 2 | 185
Reperfusion Injury 2 | 86
Seizures 2 | 596
Skin cancer 2 | 469
Status Epilepticus 2 | 98
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
atypical teratoid/rhabdoid tumor 2 | 357
medulloblastoma 2 | 720

Tissue

Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Blood and immune system 33 | 16,909
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 32 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 12 | 12,091
Kinase 9 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

execution phase of apoptosis 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045