Development Level

Tchem 17 | 1,598
Tbio 16 | 11,445
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal vitreous body morphol... 2 | 10
hyperactivity 2 | 148
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased body weight 1 | 161
decreased granulocyte number 1 | 6
decreased hematocrit 1 | 46
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased B cell number 1 | 9
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 27 | 11,493
ovarian cancer 19 | 8,520
Cancer 18 | 2,499
osteosarcoma 16 | 7,950
lung cancer 14 | 4,740
Kidney cancer 11 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
psoriasis 11 | 6,694
glioblastoma 10 | 5,792
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
medulloblastoma, large-cell 9 | 6,241
Breast cancer 8 | 3,578
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
atypical teratoid / rhabdoid tumor 6 | 5,112
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Multiple myeloma 5 | 1,332
Parkinson's disease 5 | 392
Pick disease 5 | 1,894
Splenomegaly 5 | 190
Stomach Neoplasms 5 | 300
invasive ductal carcinoma 5 | 2,951
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Breast Neoplasms 4 | 445
Hypertension 4 | 396
Intellectual disability 4 | 1,016
Mammary Neoplasms 4 | 425
Myocardial Reperfusion Injury 4 | 37
Rheumatoid arthritis 4 | 1,191
Somatic mutation 4 | 61
Toxic encephalopathy 4 | 141
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
tuberculosis 4 | 2,010
Atopic dermatitis 3 | 952
Autoimmune lymphoproliferative syndrome 3 | 11
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Squamous Cell 3 | 110
Colorectal Neoplasms 3 | 243
Edema 3 | 81
Failure to gain weight 3 | 365
Hemangioma 3 | 69
Huntington's disease 3 | 76
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Melanoma 3 | 711
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Retinal Detachment 3 | 51
Schizophrenia 3 | 1,160
Skin Neoplasms 3 | 69
Squamous cell carcinoma 3 | 129
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
non-small cell lung carcinoma 3 | 317
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Adenoma 2 | 167
Brain Ischemia 2 | 110
Dermatitis, Allergic Contact 2 | 67
Endometrial cancer 2 | 311
Heart disease 2 | 306
Hepatomegaly 2 | 285
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Lung disease 2 | 142
Myopathy 2 | 185
Reperfusion Injury 2 | 86
Seizures 2 | 596
Skin cancer 2 | 469
Status Epilepticus 2 | 98
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
atypical teratoid/rhabdoid tumor 2 | 357
medulloblastoma 2 | 720

Tissue

Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Blood and immune system 33 | 16,909
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 32 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 12 | 12,091
Kinase 9 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

execution phase of apoptosis 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apoptotic chromatin condensation inducer in the nucleus ACIN1 Tbio Non-IDG -1.51987 31.1 429
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121
Serine/threonine-protein kinase 24 STK24 Tchem Kinase -2.24110 132.9 243
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Caspase-14 CASP14 Tchem Enzyme -1.81937 73.7 348
B-cell receptor-associated protein 31 BCAP31 Tbio Non-IDG -1.70781 57.4 398
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013