Development Level

Tbio 25 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
increased blood urea nitrogen ... 2 | 48
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased circulating triglyce... 1 | 79
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total retina thickne... 1 | 4
male infertility 1 | 123
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 26 | 11,493
psoriasis 22 | 6,694
Autosomal recessive predisposition 15 | 1,442
Kidney disease 15 | 430
osteosarcoma 12 | 7,950
ovarian cancer 11 | 8,520
Failure to gain weight 10 | 365
Hypertension 10 | 396
Pediatric failure to thrive 10 | 365
Hypertensive disease 8 | 292
Hypokalemia 8 | 52
Kidney Failure 8 | 111
Renal Insufficiency 8 | 90
Renal failure in adulthood 8 | 76
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Edema 7 | 81
Nephrocalcinosis 7 | 35
Polyuria 7 | 23
lung adenocarcinoma 7 | 2,716
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
ulcerative colitis 7 | 1,819
Breast cancer 6 | 3,578
Constipation 6 | 181
Dehydration 6 | 40
Dull intelligence 6 | 645
Hyperaldosteronism 6 | 35
Hyponatremia 6 | 25
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Metabolic acidosis 6 | 90
Nephrogenic Diabetes Insipidus 6 | 16
Poor school performance 6 | 645
Proteinuria 6 | 144
Vomiting 6 | 116
adult high grade glioma 6 | 3,801
cystic fibrosis 6 | 1,696
interstitial cystitis 6 | 2,312
lung cancer 6 | 4,740
Anemia 5 | 365
Calcinosis 5 | 70
Cancer 5 | 2,499
Diarrhea 5 | 253
Dyschezia 5 | 135
Feeding difficulties in infancy 5 | 175
Growth delay 5 | 114
Growth failure 5 | 114
Growth retardation 5 | 115
Hyperactive renin-angiotensin system 5 | 8
Increased calcium level in kidney 5 | 21
Increased plasma renin activity 5 | 8
Kidney Diseases 5 | 114
Polydipsia 5 | 15
Polyhydramnios 5 | 108
Poor growth 5 | 114
Renal salt wasting 5 | 18
Short stature 5 | 531
Very poor growth 5 | 114
active Crohn's disease 5 | 922
glioblastoma 5 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
tuberculosis 5 | 2,010
Bartter disease 4 | 13
Epilepsy 4 | 792
Hypochloremia (disorder) 4 | 6
Impairment of urinary concentration 4 | 5
Kidney damage 4 | 25
Liver Cirrhosis, Experimental 4 | 769
Meniere's disease 4 | 24
Nephrolithiasis 4 | 56
Nephrotic Syndrome 4 | 78
Premature Birth 4 | 77
Premature birth of newborn 4 | 67
Seizures 4 | 596
Sensorineural hearing loss 4 | 106
Serum chloride level decreased (finding) 4 | 6
Tubular atrophy 4 | 10
adrenocortical carcinoma 4 | 1,428
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Astrocytoma, Pilocytic 3 | 3,081
Coronary artery disease 3 | 268
Focal glomerulosclerosis 3 | 37
Kidney cancer 3 | 2,613
Prenatal onset 3 | 139
Prostatic Neoplasms 3 | 495
active ulcerative colitis 3 | 764
colon cancer 3 | 1,478
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398

Tissue

Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Urinary Tract 36 | 16,678
Female tissues 35 | 17,400
Nervous System 35 | 16,725
Blood and immune system 33 | 16,909
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Respiratory system 28 | 16,393
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 7 | 4,145
Ion Channel 7 | 344
GPCR 4 | 408
Transporter 4 | 473
Transcription Factor 2 | 1,400

GO Process

excretion 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Aquaporin-6 AQP6 Tbio Non-IDG -1.52088 32.7 57
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Nuclear factor of activated T-cells 5 NFAT5 Tbio Transcription Factor -2.23838 214.7 193
Aquaporin-9 AQP9 Tbio Non-IDG -2.13315 155.0 84
ATP-sensitive inward rectifier potassium channel 1 KCNJ1 Tchem Ion Channel -2.50371 327.8 188
Chloride anion exchanger SLC26A3 Tbio Transporter -2.83731 669.8 49
Aquaporin-7 AQP7 Tbio Non-IDG -2.03961 165.7 101
Solute carrier family 22 member 18 SLC22A18 Tbio Transporter -2.37972 229.8 107
Podocin NPHS2 Tbio Non-IDG -2.59327 375.7 96