Development Level

Tbio 7 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased exploration in new e... 1 | 11
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
preweaning lethality, incomple... 1 | 499

Disease

malignant mesothelioma 7 | 3,232
Carcinoma 6 | 11,493
psoriasis 6 | 6,694
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
medulloblastoma, large-cell 4 | 6,241
Breast cancer 3 | 3,578
Congenital adrenal hyperplasia 3 | 73
Endometriosis 3 | 540
Hyperandrogenism 3 | 34
Infertility 3 | 188
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
active Crohn's disease 3 | 922
Anovulation 2 | 21
Autosomal recessive predisposition 2 | 1,442
Endometrial Neoplasms 2 | 55
Hypogonadism 2 | 173
Luteoma 2 | 4
Multiple myeloma 2 | 1,332
Pseudohermaphroditism 2 | 16
Testicular Leydig cell tumor 2 | 2
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
ulcerative colitis 2 | 1,819
Acanthosis Nigricans 1 | 27
Acne vulgaris 1 | 14
Adenocarcinoma 1 | 122
Advanced bone age 1 | 35
Age related macular degeneration 1 | 72
Amenorrhea 1 | 58
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
Bone pain 1 | 42
Breast Neoplasms 1 | 445
Carcinoma of female breast 1 | 20
Chemotherapy-induced nausea and vomiting 1 | 16
Contraception 1 | 15
Cushing's syndrome 1 | 48
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Endometrial cancer 1 | 311
Enlarged polycystic ovaries 1 | 10
Esophageal Neoplasms 1 | 69
Fatty Liver 1 | 70
Female infertility 1 | 30
Fibrosis 1 | 44
GLUCOCORTICOID DEFICIENCY 1 1 | 5
Generalized hirsutism 1 | 36
Generalized osteopenia 1 | 99
Gestational diabetes 1 | 26
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Gynecomastia 1 | 64
Hyperaldosteronism 1 | 35
Hyperlipidemia 1 | 43
Hypospadias 1 | 53
Infertility, Female 1 | 28
Insulin Resistance 1 | 72
Knee joint valgus deformity 1 | 56
Liver Cirrhosis, Experimental 1 | 769
Mammary Neoplasms 1 | 425
Myopia 1 | 176
Neoplasm Metastasis 1 | 168
Neuroblastoma 1 | 80
Osteopenia 1 | 99
Osteoporosis 1 | 363
Ovarian dysfunction 1 | 18
Ovarian hyperstimulation syndrome 1 | 19
Penile hypospadias 1 | 106
Poor growth 1 | 114
Premature ovarian failure 1 | 65
Prevention of Post-Operative Nausea and Vomiting 1 | 14
Prevention of Radiation-Induced Nausea and Vomiting 1 | 7
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Recurrence 1 | 33
Refractive error 1 | 50
Steatohepatitis 1 | 44
Tall stature 1 | 34
Very poor growth 1 | 114
active ulcerative colitis 1 | 764
adrenocortical adenoma 1 | 131
substance-related disorder 1 | 162

Tissue

Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Blood and immune system 12 | 16,909
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Respiratory system 10 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 1 | 12,091

GO Process

estrogen biosynthetic process 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Retinol dehydrogenase 8 RDH8 Tbio Enzyme -1.04003 12.6 0
Estradiol 17-beta-dehydrogenase 11 HSD17B11 Tbio Enzyme -0.99026 11.0 141
Very-long-chain 3-oxoacyl-CoA reductase HSD17B12 Tbio Enzyme -1.58879 36.7 136
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Aldo-keto reductase family 1 member B15 AKR1B15 Tbio Enzyme -0.24304 2.90 6
Dehydrogenase/reductase SDR family member 11 DHRS11 Tbio Enzyme -0.26324 1.91 126
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.36315 220.8 198
17-beta-hydroxysteroid dehydrogenase 14 HSD17B14 Tchem Enzyme -0.76122 5.51 84
Estradiol 17-beta-dehydrogenase 2 HSD17B2 Tchem Enzyme -1.92628 78.8 209