Development Level

Tbio 26 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal retina morphology 2 | 71
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal locomotor activation 1 | 16
abnormal optic disc morphology 1 | 10
abnormal retinal inner nuclear... 1 | 8
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 19 | 11,493
ovarian cancer 17 | 8,520
ependymoma 16 | 4,679
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
lung cancer 15 | 4,740
psoriasis 14 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
osteosarcoma 13 | 7,950
Breast cancer 12 | 3,578
oligodendroglioma 12 | 2,850
adult high grade glioma 11 | 3,801
astrocytic glioma 10 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Astrocytoma, Pilocytic 9 | 3,081
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung carcinoma 9 | 2,843
Cancer 8 | 2,499
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
pancreatic cancer 8 | 2,398
primitive neuroectodermal tumor 8 | 3,035
Kidney cancer 7 | 2,613
Pick disease 7 | 1,894
astrocytoma 6 | 1,146
Obesity 5 | 678
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Autosomal recessive predisposition 4 | 1,442
Intellectual disability 4 | 1,016
Waldenstrons macroglobulinemia 4 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
lung adenocarcinoma 4 | 2,716
Anteverted nostril 3 | 191
Asthma 3 | 385
Cataract 3 | 297
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Lens Opacities 3 | 231
Low Vision 3 | 174
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Nystagmus 3 | 317
Optic Atrophy 3 | 242
Parkinson's disease 3 | 392
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Visual Impairment 3 | 174
Wiskott-Aldrich syndrome 3 | 30
chronic rhinosinusitis 3 | 512
diabetes mellitus 3 | 1,728
gastric cancer 3 | 459
group 4 medulloblastoma 3 | 1,855
hereditary spastic paraplegia 3 | 318
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
Abnormality of retinal pigmentation 2 | 111
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Broad flat nasal bridge 2 | 236
Colorectal Neoplasms 2 | 243
Conductive hearing loss 2 | 123
Down syndrome 2 | 499
Electroretinogram abnormal 2 | 95
Gaucher disease type 1 2 | 180
Glaucoma 2 | 239
Liver cancer 2 | 604
Nasal bridge wide 2 | 236
Night Blindness 2 | 101
Ophthalmoplegia 2 | 106
Retinal pigment epithelial abnormality 2 | 111
Sensorineural Hearing Loss (disorder) 2 | 284
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
hepatocellular carcinoma 2 | 547
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
tuberculosis 2 | 2,010

Tissue

Blood and immune system 29 | 16,909
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Digestive Tract 28 | 17,369
Nervous System 28 | 16,725
Urinary Tract 28 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634

GO Process

establishment or maintenance o... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Actin-related protein 2 ACTR2 Tbio Non-IDG -1.88412 78.5 211
Capping protein, Arp2/3 and myosin-I linker protein 2 CARMIL2 Tbio Non-IDG -0.95074 9.07 5
CLIP-associating protein 1 CLASP1 Tbio Non-IDG -1.29173 19.3 219
Protein crumbs homolog 1 CRB1 Tbio Non-IDG -2.21993 162.3 31
T-cell surface glycoprotein CD3 gamma chain CD3G Tclin Non-IDG -2.34430 223.5 239
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Protocadherin Fat 1 FAT1 Tbio Non-IDG -2.45270 303.5 93
Secreted frizzled-related protein 5 SFRP5 Tbio Non-IDG -1.81796 74.9 180
Adenylyl cyclase-associated protein 1 CAP1 Tbio Enzyme -1.03272 8.93 160