Development Level

Tbio 8 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

psoriasis 7 | 6,694
ovarian cancer 6 | 8,520
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
pancreatic cancer 5 | 2,398
Carcinoma 4 | 11,493
lung cancer 4 | 4,740
tuberculosis 4 | 2,010
Autosomal recessive predisposition 3 | 1,442
Dysarthria 3 | 192
Kidney cancer 3 | 2,613
Muscle hypotonia 3 | 571
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
non-small cell lung cancer 3 | 2,890
Acquired scoliosis 2 | 281
Blepharoptosis 2 | 231
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Carcinoma, Hepatocellular 2 | 228
Cognitive delay 2 | 608
Curvature of spine 2 | 282
Deglutition Disorders 2 | 132
Down syndrome 2 | 499
Dull intelligence 2 | 645
Epilepsy 2 | 792
Feeding difficulties in infancy 2 | 175
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Immune system cancer 2 | 140
Intellectual disability 2 | 1,016
Liver carcinoma 2 | 240
Low intelligence 2 | 645
Lymphoid leukemia 2 | 160
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Obesity 2 | 678
Poor school performance 2 | 645
Seizures 2 | 596
Splenomegaly 2 | 190
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
limb girdle muscular dystrophy 2A 2 | 213
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
Abnormal dermatoglyphic pattern 1 | 24
Abnormal platelet function 1 | 12
Anomalous pulmonary artery 1 | 4
Bitemporal Hemianopia 1 | 2
Broad chest 1 | 8
Bundle-Branch Block 1 | 8
Cafe au lait spots, multiple 1 | 17
Carcinoma of lung 1 | 3
Cardio-facio-cutaneous syndrome 1 | 6
Central Diabetes Insipidus 1 | 5
Congenital bronchogenic cyst 1 | 3
Connective tissue cancer 1 | 10
Costello syndrome (disorder) 1 | 6
Craniopharyngioma 1 | 16
Deep palmar crease 1 | 8
EARLOBE CREASE 1 | 1
Excess nuchal skin 1 | 30
Hairy Cell Leukemia 1 | 5
Hashimoto-Pritzker syndrome 1 | 1
Hyperextensible digits 1 | 7
Long palpebral fissure 1 | 17
Mandibular Neoplasms 1 | 1
Multiple lentigines 1 | 10
Multiple palmar creases 1 | 1
Multiple plantar creases 1 | 1
Neurofibrosarcoma 1 | 7
Numerous nevi 1 | 5
Papule 1 | 43
Partial to total absence of eyelashes 1 | 7
Pectus carinatum superiorly 1 | 4
Pectus excavatum inferiorly 1 | 5
Pituitary gland enlarged 1 | 2
Secondary Adrenal Insufficiency 1 | 6
Senile lentigo 1 | 10
Shield chest 1 | 8
Skin nodule 1 | 3
Slow decrease in visual acuity 1 | 13
Slow-growing hair 1 | 19
Small intestine cancer 1 | 12
Sparse to absent eyelashes 1 | 7
Submucous cleft of hard palate 1 | 11
Thickened helices 1 | 15
Tongue thrusting 1 | 2
Visual field tests abnormal 1 | 2
pre-malignant neoplasm 1 | 2

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 4 | 4,145
Non-IDG 4 | 12,091
Kinase 1 | 634

GO Process

establishment of protein local... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase B-raf BRAF Tclin Kinase -2.33582 220.9 1431
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Ras-related protein Rab-10 RAB10 Tbio Enzyme -1.62208 41.1 164
Acetylcholinesterase collagenic tail peptide COLQ Tbio Enzyme -1.69962 61.3 122
Ras-related protein Rab-11B RAB11B Tbio Enzyme -1.87884 68.3 108
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.77 107
FERM and PDZ domain-containing protein 1 FRMPD1 Tbio Non-IDG -0.91695 8.18 88