Development Level

Tbio 21 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased lean body mass 3 | 135
abnormal cornea morphology 2 | 31
abnormal lens morphology 2 | 81
cataract 2 | 92
corneal opacity 2 | 32
decreased body weight 2 | 161
preweaning lethality, incomple... 2 | 499
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye pigmentation 1 | 3
abnormal head morphology 1 | 10
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tail morphology 1 | 25
absent pinna reflex 1 | 23
corneal vascularization 1 | 6
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
female infertility 1 | 60
fused cornea and lens 1 | 5
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 15 | 11,493
ovarian cancer 14 | 8,520
glioblastoma 11 | 5,792
psoriasis 11 | 6,694
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Intellectual disability 8 | 1,016
lung cancer 8 | 4,740
Astrocytoma, Pilocytic 7 | 3,081
Breast cancer 7 | 3,578
adrenocortical carcinoma 7 | 1,428
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
oligodendroglioma 7 | 2,850
primitive neuroectodermal tumor 7 | 3,035
malignant mesothelioma 6 | 3,232
subependymal giant cell astrocytoma 6 | 2,287
Cancer 5 | 2,499
Kidney cancer 5 | 2,613
Microcephaly 5 | 166
invasive ductal carcinoma 5 | 2,951
non-small cell lung cancer 5 | 2,890
Cerebellar Hypoplasia 4 | 61
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Schizophrenia 4 | 1,160
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Autosomal recessive predisposition 3 | 1,442
Cleft Palate 3 | 271
Craniofacial Abnormalities 3 | 151
Dilated ventricles (finding) 3 | 121
Dull intelligence 3 | 645
Epilepsy 3 | 792
Hyperreflexia 3 | 209
Lissencephaly 3 | 69
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Seizures 3 | 596
Short stature 3 | 531
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Anteverted nostril 2 | 191
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Bradykinesia 2 | 34
Cerebral atrophy 2 | 178
Depressive disorder 2 | 409
Electroencephalogram abnormal 2 | 101
Endometriosis 2 | 540
Highly variable severity 2 | 157
Hypoplasia of the brainstem 2 | 22
Large auricle 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Macrotia 2 | 87
Mental Depression 2 | 333
Miller-Dieker lissencephaly syndrome 2 | 19
Mood Disorders 2 | 184
Movement Disorders 2 | 55
Multiple myeloma 2 | 1,332
Muscle Spasticity 2 | 195
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Pachygyria 2 | 41
Parkinson's disease 2 | 392
Psychotic Disorders 2 | 151
Skeletal muscle atrophy 2 | 139
Variable expressivity 2 | 157
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
atypical teratoid/rhabdoid tumor 2 | 357
dermatomyositis 2 | 966
muscle degeneration 2 | 139
nasopharyngeal carcinoma 2 | 1,058
posterior fossa group B ependymoma 2 | 416
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

establishment of mitotic spind... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Suppressor APC domain-containing protein 2 SAPCD2 Tbio Non-IDG -1.10655 16.6 38
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.30647 213.2 45
CDK5 regulatory subunit-associated protein 2 CDK5RAP2 Tbio Non-IDG -1.70804 54.4 81
Microcephalin MCPH1 Tbio Non-IDG -1.96863 109.3 260
G-protein-signaling modulator 2 GPSM2 Tbio Non-IDG -2.92381 834.6 138
Rho guanine nucleotide exchange factor 2 ARHGEF2 Tbio Non-IDG -1.64721 53.8 302