Development Level

Tbio 3 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased grip strength 1 | 116
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged testis 1 | 6
hypoactivity 1 | 132
increased body weight 1 | 25
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 3 | 11,493
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
Abnormal liver function tests during pregnancy 1 | 2
Abnormal liver function tests during pregnancy, resolves postpartum 1 | 2
Alkaline phosphatase serum increased 1 | 29
Animal Mammary Neoplasms 1 | 136
Astrocytoma, Pilocytic 1 | 3,081
Biliary cirrhosis 1 | 45
Bipolar Disorder 1 | 666
CHOLESTASIS, INTRAHEPATIC, OF PREGNANCY 3 1 | 1
CHOLESTASIS, INTRAHEPATIC, OF PREGNANCY, 1 1 | 2
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Cholangitis 1 | 32
Cholangitis, Sclerosing 1 | 6
Cholecystitis 1 | 18
Cholecystolithiasis 1 | 5
Cholelithiasis 1 | 33
Cholestasis 1 | 155
Cholestasis of pregnancy 1 | 5
Cholestasis, progressive familial intrahepatic 1 1 | 3
Cholestasis, progressive familial intrahepatic 3 1 | 1
Cholesterol gallstones 1 | 2
Clostridium difficile colitis 1 | 12
Colorectal Neoplasms 1 | 243
Diarrhea 1 | 253
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Elevated hepatic transaminases 1 | 81
End Stage Liver Disease 1 | 4
Fibrosis, Liver 1 | 32
Gallbladder Disease 1 1 | 1
Hepatic enzyme increased 1 | 81
Hepatomegaly 1 | 285
Icterus 1 | 82
Increased serum bile acid concentration during pregnancy 1 | 2
Increased serum bile acid concentration during pregnancy, resolves 1 | 2
Infantile onset 1 | 238
Inflammation 1 | 120
Inguinal hernia 1 | 14
Intrahepatic Cholestasis of Pregnancy 1 | 4
Intrahepatic cholestasis 1 | 20
Jaundice, Obstructive 1 | 1
Kidney cancer 1 | 2,613
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Biliary 1 | 33
Liver Dysfunction 1 | 99
Liver cancer 1 | 604
Liver carcinoma 1 | 240
Liver disease 1 | 237
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Low phospholipid-associated cholelithiasis 1 | 1
MICROCEPHALY 15, PRIMARY, AUTOSOMAL RECESSIVE 1 | 1
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
Malabsorption 1 | 82
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Microcephaly 1 | 166
Non-alcoholic Fatty Liver Disease 1 | 42
Obstructive jaundice 1 | 7
Pancreatitis 1 | 123
Paragonimiasis 1 | 8
Portal fibrosis 1 | 2
Portal fibrosis shown on biopsy 1 | 2
Premature Birth 1 | 77
Premature birth of newborn 1 | 67
Primary autosomal recessive microcephaly 15 1 | 1
Progressive intrahepatic cholestasis 1 | 4
Progressive intrahepatic cholestasis (disorder) 1 | 3
Pruritus 1 | 58
Speech Disorders 1 | 58
Subclinical abnormal liver function tests 1 | 81
Transaminases increased 1 | 81
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,158
aldosterone-producing adenoma 1 | 665
cutaneous lupus erythematosus 1 | 1,057
esophageal adenocarcinoma 1 | 737
inflammatory breast cancer 1 | 286
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
sarcoidosis 1 | 370
sclerosing cholangitis 1 | 1
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Transporter 1 | 473

GO Process

establishment of blood-brain b... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73
Phosphatidylcholine translocator ABCB4 ABCB4 Tbio Transporter -2.91346 806.6 146
Lipolysis-stimulated lipoprotein receptor LSR Tbio Non-IDG -1.92670 81.8 89