Development Level

Tbio 11 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal vertebrae morphology 1 | 18
cleft palate 1 | 8
cyanosis 1 | 7
decreased bone mineral density 1 | 126
edema 1 | 59
enlarged heart 1 | 210
increased leukocyte cell numbe... 1 | 47
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19

Disease

Cancer 8 | 2,499
Carcinoma 8 | 11,493
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
Breast Neoplasms 5 | 445
Breast cancer 5 | 3,578
Craniofacial Abnormalities 5 | 151
Mammary Neoplasms 5 | 425
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
osteosarcoma 5 | 7,950
Astrocytoma, Pilocytic 4 | 3,081
Sparse hair 4 | 59
Thin, sparse hair 4 | 59
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Brachydactyly 3 | 156
Cleft Lip 3 | 141
Cleft Palate 3 | 271
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Hemangioma, Cavernous 3 | 20
Pediatric failure to thrive 3 | 365
Polydactyly 3 | 107
Seizures 3 | 596
Small head 3 | 374
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Telangiectasis 3 | 36
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Abnormality of pulmonary valve 2 | 23
Abnormality of the voice 2 | 46
Alzheimer's disease 2 | 658
Anemia 2 | 365
Aplasia Cutis Congenita 2 | 14
Carcinoma, Pancreatic Ductal 2 | 20
Cell Transformation, Neoplastic 2 | 97
Cholecystitis 2 | 18
Congenital scar 2 | 13
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Epistaxis 2 | 43
Fine hair 2 | 42
Heart disease 2 | 306
Hematochezia 2 | 9
Hemoglobin low 2 | 124
Hereditary hemorrhagic telangiectasia 2 | 13
Hypertension 2 | 396
Hypertension, Portal 2 | 22
Hypoplasia of the maxilla 2 | 66
Hypotrophic maxilla 2 | 66
Intermittent migraine headaches 2 | 68
Iron-Refractory Iron Deficiency Anemia 2 | 15
Juvenile polyposis syndrome 2 | 7
Kidney cancer 2 | 2,613
Liver Cirrhosis 2 | 181
Maxillary retrognathia 2 | 66
Migraine Disorders 2 | 76
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neoplastic Cell Transformation 2 | 89
Osteoarthritis 2 | 184
Parietal foramina 2 | 10
Retrusion of upper jaw bones 2 | 66
Short distal phalanges 2 | 50
Spontaneous haematoma 2 | 8
Syndactyly of fingers 2 | 48
Synostosis 2 | 15
Telangiectasia of the skin 2 | 39
Tetralogy of Fallot 2 | 63
Thyroid cancer, papillary 2 | 14
Tooth agenesis 2 | 44
Visceral angiomatosis 2 | 13
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
fibroadenoma 2 | 559
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Transcription Factor 8 | 1,400
Non-IDG 4 | 12,091

GO Process

epithelial to mesenchymal tran... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Hairy/enhancer-of-split related with YRPW motif protein 1 HEY1 Tbio Transcription Factor -2.28398 163.4 335
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.28636 1782.9 566
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266
Homeobox protein MSX-2 MSX2 Tbio Transcription Factor -2.43910 277.8 324
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916