Development Level

Tbio 35 | 11,651
Tchem 17 | 1,388
Tclin 4 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
decreased leukocyte cell numbe... 2 | 73
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coping response 1 | 1
abnormal cornea morphology 1 | 31
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal vibrissa morphology 1 | 25
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating glucose ... 1 | 24
increased heart left ventricle... 1 | 4
increased mean corpuscular vol... 1 | 92
increased vertical activity 1 | 24
prenatal lethality 1 | 28

Disease

Carcinoma 45 | 11,493
Cancer 39 | 2,499
osteosarcoma 38 | 7,950
ovarian cancer 37 | 8,520
glioblastoma 30 | 5,792
Breast cancer 26 | 3,578
lung cancer 26 | 4,740
psoriasis 25 | 6,694
medulloblastoma, large-cell 23 | 6,241
Kidney cancer 21 | 2,613
atypical teratoid / rhabdoid tumor 21 | 5,112
ependymoma 21 | 4,679
pancreatic cancer 21 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung adenocarcinoma 17 | 2,716
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
non-small cell lung cancer 16 | 2,890
astrocytic glioma 15 | 2,597
oligodendroglioma 15 | 2,850
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
juvenile dermatomyositis 14 | 1,187
malignant mesothelioma 14 | 3,232
pituitary cancer 14 | 1,972
primitive neuroectodermal tumor 14 | 3,035
subependymal giant cell astrocytoma 14 | 2,287
Breast Neoplasms 13 | 445
Mammary Neoplasms 13 | 425
cystic fibrosis 13 | 1,696
lung carcinoma 13 | 2,843
ulcerative colitis 13 | 1,819
Pick disease 12 | 1,894
Rheumatoid arthritis 12 | 1,191
diabetes mellitus 12 | 1,728
interstitial cystitis 12 | 2,312
primary pancreatic ductal adenocarcinoma 12 | 1,109
Adenocarcinoma 10 | 122
Stomach Neoplasms 10 | 300
acute quadriplegic myopathy 10 | 1,158
breast carcinoma 10 | 1,638
spina bifida 10 | 1,074
Autosomal recessive predisposition 9 | 1,442
Carcinoma, Squamous Cell 9 | 110
Hypoplastic mandible condyle 9 | 275
Lung Neoplasms 9 | 232
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Orbital separation excessive 9 | 244
Schizophrenia 9 | 1,160
Squamous cell carcinoma 9 | 129
colon cancer 9 | 1,478
Acquired scoliosis 8 | 281
Carcinoma, Hepatocellular 8 | 228
Colorectal Neoplasms 8 | 243
Curvature of spine 8 | 282
Downward slant of palpebral fissure 8 | 158
Liver carcinoma 8 | 240
Melanoma 8 | 711
Muscle hypotonia 8 | 571
Neoplasm Invasiveness 8 | 161
Blepharoptosis 7 | 231
Byzanthine arch palate 7 | 194
Concave bridge of nose 7 | 195
Cryptorchidism 7 | 296
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Endometriosis 7 | 540
Noonan syndrome 7 | 34
Pectus excavatum 7 | 100
adrenocortical carcinoma 7 | 1,428
dermatomyositis 7 | 966
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
hepatocellular carcinoma 7 | 547
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
tuberculosis 7 | 2,010
Congenital Epicanthus 6 | 177
Delayed bone age 6 | 136
Down syndrome 6 | 499
Exophthalmos 6 | 112
Frontal bossing 6 | 157
Heart disease 6 | 306
High forehead 6 | 102
Immune system cancer 6 | 140
Increased head circumference 6 | 147
Joint hyperflexibility 6 | 78
Liver Cirrhosis 6 | 181
Prominent eyes 6 | 96
Prominent globes 6 | 96
Prostatic Neoplasms 6 | 495
Protruding eyes 6 | 96
Short neck 6 | 140
Short stature 6 | 531
Tall forehead 6 | 102
Triangular face 6 | 58
astrocytoma 6 | 1,146
pediatric high grade glioma 6 | 1,064

Tissue

Digestive Tract 56 | 17,369
Endocrine System 56 | 18,159
Liver and Pancreas 56 | 16,750
Blood and immune system 55 | 16,909
Female tissues 55 | 17,400
Male tissues 55 | 17,142
Nervous System 55 | 16,725
Respiratory system 55 | 16,393
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 14 | 634
Enzyme 12 | 4,145
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

epidermal growth factor recept... 56 | 56
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase CBL-B CBLB Tbio Enzyme -0.82313 6.58 193
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 PAG1 Tbio Non-IDG -1.69647 50.1 216
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Cytoplasmic protein NCK2 NCK2 Tbio Non-IDG -1.57587 36.4 241
Erbin ERBIN Tbio Non-IDG -1.72357 59.1 117
Amphiregulin AREG Tbio Non-IDG -2.59721 307.5 389
EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 Tbio Non-IDG -2.17305 162.6 259
Tyrosine-protein kinase CSK CSK Tchem Kinase -2.54736 271.3 547
Disintegrin and metalloproteinase domain-containing protein 17 ADAM17 Tchem Enzyme -3.55216 3569.0 718