Development Level

Tchem 1 | 1,598

Disease

AUDITORY NEUROPATHY, AUTOSOMAL DOMINANT, 1 1 | 2
Abnormality of the iris 1 | 14
Abortion, Spontaneous 1 | 109
Acquired flat foot 1 | 72
Acquired scoliosis 1 | 281
Aneurysm, Dissecting 1 | 8
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm 1 | 38
Aortic aneurysm, familial thoracic 3 1 | 13
Arachnodactyly 1 | 49
Arterial tortuosity 1 | 5
Arterial tortuosity syndrome 1 | 7
Ascending aortic dissection 1 | 13
Astrocytoma, Pilocytic 1 | 3,081
Atypical scarring of skin 1 | 62
Blue sclera 1 | 32
Breast cancer 1 | 3,578
Byzanthine arch palate 1 | 194
Camurati-Engelmann disease 1 | 6
Cancer 1 | 2,499
Carcinoma 1 | 11,493
Cardiomegaly 1 | 116
Chemical and Drug Induced Liver Injury 1 | 195
Chest Pain 1 | 38
Cleft Palate 1 | 271
Cleft palate with cleft lip 1 | 23
Cleft uvula 1 | 27
Colorectal Neoplasms 1 | 243
Coronary artery disease 1 | 268
Craniosynostosis 1 | 74
Curvature of spine 1 | 282
Cutis marmorata 1 | 32
Cystic medial necrosis of aorta 1 | 13
Descending aortic dissection 1 | 13
Dissection of aorta 1 | 9
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Ehlers-Danlos syndrome 1 | 43
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Flatfoot 1 | 73
Flexion contracture of proximal interphalangeal joint 1 | 75
Gaucher disease type 1 1 | 180
Hereditary hemorrhagic telangiectasia 1 | 13
Hypertensive disease 1 | 292
Hypoplastic mandible condyle 1 | 275
Hypotrophic malar bone 1 | 129
Idiopathic pulmonary fibrosis 1 | 23
Impaired left ventricular function 1 | 16
Increase in blood pressure 1 | 119
Keratoacanthoma familial 1 | 1
Kidney cancer 1 | 2,613
Left-Sided Heart Failure 1 | 16
Linear atrophy 1 | 15
Liver Cirrhosis 1 | 181
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Loeys-Dietz Syndrome 1 1 | 1
Loeys-Dietz syndrome 1 | 23
MULTIPLE SELF-HEALING SQUAMOUS EPITHELIOMA, SUSCEPTIBILITY TO 1 | 1
Macular degeneration 1 | 65
Malar flattening 1 | 129
Mandibular hypoplasia 1 | 275
Micrognathism 1 | 275
Multiple self-healing squamous epithelioma 1 | 1
Oral cleft 1 | 18
Orbital separation excessive 1 | 244
Patent ductus arteriosus 1 | 90
Prostate cancer 1 | 175
Pulmonary Fibrosis 1 | 106
Skin Neoplasms 1 | 69
Skull malformation 1 | 38
Spontaneous abortion 1 | 113
Systemic scleroderma 1 | 60
Tall stature 1 | 34
Thoracic aortic aneurysm 1 | 15
Uremia 1 | 19
Ureteral obstruction 1 | 33
Uterine Rupture 1 | 2
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
astrocytoma 1 | 1,146
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
juvenile dermatomyositis 1 | 1,187
medulloblastoma, large-cell 1 | 6,241
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
primitive neuroectodermal tumor 1 | 3,035

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Kinase 1 | 634

GO Process

epicardium morphogenesis 1 | 1
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413