Development Level

Tbio 7 | 11,445
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
group 3 medulloblastoma 7 | 4,104
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
Hirschsprung's disease 6 | 46
Megacolon 6 | 29
ependymoma 6 | 4,679
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Congenital central hypoventilation syndrome 5 | 18
Constipation 5 | 181
Dyschezia 5 | 135
Hirschsprung Disease 5 | 31
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
oligodendroglioma 5 | 2,850
Abdominal Pain 4 | 98
Autonomic dysregulation 4 | 6
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Intestinal Obstruction 4 | 31
Low set ears 4 | 181
Muscle hypotonia 4 | 571
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
Astrocytoma, Pilocytic 3 | 3,081
Body Temperature Changes 3 | 10
Broad flat nasal bridge 3 | 236
Cardiovascular Abnormalities 3 | 31
Cardiovascular Diseases 3 | 59
Central hypoventilation 3 | 8
Cognitive delay 3 | 608
Congenital central hypoventilation 3 | 6
Downward slant of palpebral fissure 3 | 158
Dull intelligence 3 | 645
Epilepsy 3 | 792
Feeding difficulties 3 | 127
Ganglioneuroblastoma 3 | 11
Ganglioneuroma 3 | 13
Global developmental delay 3 | 608
Heart failure 3 | 162
Hyperhidrosis disorder 3 | 81
Increased sweating 3 | 81
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Mouth Abnormalities 3 | 14
Multiple endocrine neoplasia type 2A 3 | 20
Multiple endocrine neoplasia type 2B 3 | 17
Nasal bridge wide 3 | 236
Nausea and vomiting 3 | 97
Peripheral Neuropathy 3 | 134
Pick disease 3 | 1,894
Poor school performance 3 | 645
Poor temperature regulation 3 | 10
Posteriorly rotated ear 3 | 61
Schizophrenia 3 | 1,160
Seizures 3 | 596
Sweating 3 | 81
Waardenburg's syndrome 3 | 17
Weight decreased 3 | 103
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
Congenital deafness 2 | 185
Congenital pes cavus 2 | 88
Congestive heart failure 2 | 113
Deafness 2 | 198
Death in early childhood 2 | 82
Death in infancy 2 | 82
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Down syndrome 2 | 499
Failure to gain weight 2 | 365
Gastroesophageal reflux disease 2 | 110
Hearing Loss, Partial 2 | 185
Heart disease 2 | 306
Heartburn 2 | 78
Hypertension 2 | 396
Kidney disease 2 | 430
Low Birth Weights 2 | 69
Neuropathy 2 | 261
Pectus excavatum 2 | 100
Pediatric failure to thrive 2 | 365
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Small for gestational age (disorder) 2 | 69
Status Epilepticus 2 | 98
Strabismus 2 | 270
hearing impairment 2 | 199
pulmonary arterial hypertension 2 | 75

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Blood and immune system 10 | 16,909
Nervous System 10 | 16,725
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Urinary Tract 9 | 16,678
Respiratory system 8 | 16,393

Target Family

Transcription Factor 5 | 1,400
GPCR 2 | 408
Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

enteric nervous system develop... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF26A KIF26A Tdark Non-IDG -0.20165 1.48 70
T-cell leukemia homeobox protein 2 TLX2 Tbio Transcription Factor -2.18879 155.8 57
Transcription factor SOX-8 SOX8 Tbio Transcription Factor -1.36449 24.3 254
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Paired mesoderm homeobox protein 2B PHOX2B Tbio Transcription Factor -2.49193 315.4 127
Endothelin-1 receptor EDNRA Tclin GPCR -2.86513 644.6 259
H2.0-like homeobox protein HLX Tbio Transcription Factor -1.82547 73.2 189
Endothelin receptor type B EDNRB Tclin GPCR -3.27771 1756.7 324
Phosphatase and actin regulator 4 PHACTR4 Tbio Enzyme -0.75900 6.19 88
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.34041 2403.4 393