Development Level

Tchem 10 | 1,598
Tbio 6 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal bone structure 2 | 187
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal pericardium morpholog... 1 | 26
cardiovascular system phenotyp... 1 | 36
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased cardiac muscle contr... 1 | 11
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased heart rate 1 | 18
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
vertebral fusion 1 | 23

Disease

ovarian cancer 12 | 8,520
Cancer 11 | 2,499
Carcinoma 11 | 11,493
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
diabetes mellitus 6 | 1,728
non-small cell lung cancer 6 | 2,890
Arthritis 5 | 290
Hypertension 5 | 396
Vascular disease 5 | 319
atypical teratoid / rhabdoid tumor 5 | 5,112
cystic fibrosis 5 | 1,696
ependymoma 5 | 4,679
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Breast Neoplasms 4 | 445
Coronary artery disease 4 | 268
Kidney disease 4 | 430
Mammary Neoplasms 4 | 425
Schizophrenia 4 | 1,160
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
Anemia 3 | 365
Atherosclerosis 3 | 291
Cell Transformation, Neoplastic 3 | 97
Chemical and Drug Induced Liver Injury 3 | 195
Heart disease 3 | 306
Hypertensive disease 3 | 292
Inflammation 3 | 120
Kidney cancer 3 | 2,613
Liver disease 3 | 237
Neoplasm Invasiveness 3 | 161
Neoplastic Cell Transformation 3 | 89
Obesity 3 | 678
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Adenocarcinoma 2 | 122
Adenoma 2 | 167
Adverse reaction to drug 2 | 61
Alzheimer's disease 2 | 658
Blood Coagulation Disorders 2 | 42
Brain disease 2 | 96
Cerebrovascular disease 2 | 238
Chronic Obstructive Airway Disease 2 | 37
Clouding of corneal stroma 2 | 50
Corneal Opacity 2 | 53
Drug-Related Side Effects and Adverse Reactions 2 | 62
Esophageal Squamous Cell Carcinoma 2 | 77
Exanthema 2 | 43
Hematuria 2 | 36
Hepatitis C 2 | 94
Hepatomegaly 2 | 285
Hypersensitivity reaction type II disease 2 | 253
Increase in blood pressure 2 | 119
Insulin Resistance 2 | 72
Kidney Failure, Chronic 2 | 46
Lipid metabolism disorder 2 | 114
Liver Cirrhosis, Experimental 2 | 769
Liver diseases 2 | 87
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Mammary Neoplasms, Experimental 2 | 154
Myocardial Ischemia 2 | 169
Non-alcoholic Fatty Liver Disease 2 | 42
Osteoporosis 2 | 363
Pancreatitis 2 | 123
Pneumonia 2 | 174
Polycystic ovary syndrome 2 | 360
Proteinuria 2 | 144
Pulmonary Disease, Chronic Obstructive 2 | 31
Pulmonary Fibrosis 2 | 106
Renal Cell Carcinoma 2 | 214
Squamous cell carcinoma of esophagus 2 | 77
Stomach Neoplasms 2 | 300
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074
Biliary cirrhosis 1 | 45

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 16 | 15,192
Female tissues 16 | 17,400
Respiratory system 16 | 16,393

Target Family

Kinase 5 | 634
Non-IDG 5 | 12,091
Enzyme 4 | 4,145
Transcription Factor 3 | 1,400

GO Process

endothelial cell proliferation 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
cAMP-dependent protein kinase catalytic subunit PRKX PRKX Tchem Kinase -1.17196 28.7 183
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Calcitonin gene-related peptide 1 CALCA Tchem Non-IDG -3.70355 8831.3 1309
Angiopoietin-1 receptor TEK Tclin Kinase -3.00257 906.7 1009
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
NADPH oxidase 5 NOX5 Tchem Enzyme -1.82693 76.8 174
THAP domain-containing protein 1 THAP1 Tbio Transcription Factor -1.99752 104.3 67