Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal iris morphology 1 | 13
abnormal retina morphology 1 | 71
increased lymphocyte cell numb... 1 | 32
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 4 | 8,520
Carcinoma 3 | 11,493
Gait abnormality 2 | 135
Multiple myeloma 2 | 1,332
Nerve Degeneration 2 | 121
Neuro-degenerative disease 2 | 43
Neurodegenerative Disorders 2 | 79
Neuropathy 2 | 261
Pick disease 2 | 1,894
osteosarcoma 2 | 7,950
progressive supranuclear palsy 2 | 676
psoriasis 2 | 6,694
Abnormal brain FDG positron emission tomography 1 | 9
Abnormality of multiple cell lineages in the bone marrow 1 | 1
Albinism, Ocular 1 | 8
Alexia 1 | 6
Alkaline phosphatase serum increased 1 | 29
Amblyopia 1 | 38
Aphasia 1 | 26
Apraxias 1 | 27
Attenuated Ch??diak-Higashi syndrome 1 | 1
Autosomal dominant Robinow syndrome 1 1 | 15
Autosomal dominant Robinow syndrome 2 1 | 22
Back Pain 1 | 7
Behavioral variant of frontotemporal dementia 1 | 8
Charcot-Marie-Tooth disease 1 | 62
Compulsive hoarding 1 | 7
Cranial nerve palsies 1 | 11
Dentin dysplasia 1 | 19
Developmental arithmetic disorder 1 | 8
Difficulty making arithmetical calculations 1 | 8
Dysgraphia 1 | 20
Dyslexia 1 | 43
Dysphasia 1 | 23
Dyspnea 1 | 76
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Edema 1 | 81
Excess nuchal skin 1 | 30
Exfoliation Syndrome 1 | 12
Fasciculation, Tongue 1 | 8
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Forgetful 1 | 40
Frontotemporal cerebral atrophy 1 | 8
Gait imbalance 1 | 17
Generalized hypopigmentation 1 | 12
Giant melanosomes in melanocytes 1 | 4
Gingival Diseases 1 | 19
Gingivitis 1 | 29
Grammar-specific speech disorder 1 | 6
Hair hypopigmentation 1 | 12
Hammer Toe 1 | 23
Hemophagocytic lymphohistiocytosis 1 | 30
Hyperorality 1 | 7
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Irritation - emotion 1 | 68
Lower limb hyperreflexia 1 | 10
Macular hypoplasia 1 | 3
Memory Loss 1 | 40
Memory impairment 1 | 40
Muscle Cramp 1 | 55
Muscle weakness of limb 1 | 21
Paget's disease of bone 1 | 36
Pain 1 | 103
Paralysed 1 | 42
Pelvic girdle weakness 1 | 7
Periodontal Diseases 1 | 21
Peripheral Neuropathy 1 | 134
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Poor speech 1 | 37
Primary Progressive Nonfluent Aphasia 1 | 7
Problems speaking 1 | 37
Progressive non-fluent aphasia 1 | 7
Recurrent bacterial skin infections 1 | 8
Recurrent cutaneous abscess formation 1 | 4
Recurrent systemic pyogenic infections 1 | 1
Reduced visual acuity 1 | 63
Reflex, Ankle, Absent 1 | 8
Repeated speech 1 | 9
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Semantic Dementia 1 | 7
Shoulder girdle muscle atrophy 1 | 6
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Skin Ulcer 1 | 48
Social disinhibition 1 | 14
Spoken Word Recognition Deficit 1 | 6
Stevens-Johnson syndrome 1 | 92
Temporal cortical atrophy 1 | 6
White hair 1 | 7
Winged scapula 1 | 23
Xerostomia 1 | 42

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145

GO Process

endosome to lysosome transport... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
UBX domain-containing protein 6 UBXN6 Tbio Non-IDG -0.94338 7.82 126
Vacuolar protein sorting-associated protein 4B VPS4B Tbio Non-IDG -1.88302 77.7 125
Transitional endoplasmic reticulum ATPase VCP Tchem Enzyme -2.84978 736.4 416