Development Level

Tbio 17 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
vertebral fusion 2 | 23
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
increased circulating total pr... 1 | 28
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 13 | 8,520
Carcinoma 10 | 11,493
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
medulloblastoma, large-cell 6 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Kidney cancer 5 | 2,613
Rheumatoid arthritis 5 | 1,191
atypical teratoid / rhabdoid tumor 5 | 5,112
Astrocytoma, Pilocytic 4 | 3,081
ependymoma 4 | 4,679
lung cancer 4 | 4,740
progressive supranuclear palsy 4 | 676
psoriasis 4 | 6,694
Alzheimer's disease 3 | 658
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
malignant mesothelioma 3 | 3,232
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 336
Anemia 2 | 365
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Epilepsy 2 | 792
Familial encephalopathy with neuroserpin inclusion bodies 2 | 10
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Pick's disease 2 | 15
Seizures 2 | 596
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
tuberculosis 2 | 2,010
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Alpha 1-antitrypsin deficiency 1 | 11
Alzheimer Disease 1 | 83
Bladder Neoplasm 1 | 112
Broad eyebrows 1 | 4
Broad flat nasal bridge 1 | 236
Carcinoma, Renal Cell 1 | 124
Congenital disorder of glycosylation 1 | 54
Disease Progression 1 | 136
Downward slant of palpebral fissure 1 | 158
Dysgerminoma 1 | 11
Gaucher disease type 1 1 | 180
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Hyperplasia of nose 1 | 23
Hypersensitivity reaction type II disease 1 | 253
Hypertrophy of nose 1 | 23
Hypotrophic malar bone 1 | 129
Infertility 1 | 188
Isolated cases 1 | 72
Large nose 1 | 23
Liver cancer 1 | 604
Long eyebrows 1 | 2
Long narrow head 1 | 75
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 15 1 | 1
Malar flattening 1 | 129
Moderate mental retardation (I.Q. 35-49) 1 | 28
Multiple Sclerosis 1 | 540
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Nasal bridge wide 1 | 236
Neuroblastoma 1 | 80
Nevoid basal cell carcinoma syndrome 1 | 16
Pain agnosia 1 | 104
Physical aggression 1 | 76
Pointed chin 1 | 33
Polycystic ovary syndrome 1 | 360
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Renal Cell Carcinoma 1 | 214
Short philtrum 1 | 53
Smooth philtrum 1 | 43
Syringomyelia 1 | 15
Thin upper lip vermilion 1 | 67
Turridolichocephaly 1 | 75
Urinary Bladder Neoplasms 1 | 114
Vitiligo 1 | 73
breast carcinoma 1 | 1,638
pediatric high grade glioma 1 | 1,064
permanent atrial fibrillation 1 | 45
sarcoidosis 1 | 370
severe Alzheimer's disease 1 | 47
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Enzyme 11 | 4,145
Non-IDG 7 | 12,091

GO Process

endoplasmic reticulum mannose ... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase RNF5 RNF5 Tbio Enzyme -1.20054 15.1 166
UDP-glucose:glycoprotein glucosyltransferase 2 UGGT2 Tbio Enzyme -0.47145 1.64 93
Protein OS-9 OS9 Tbio Non-IDG -1.76074 57.1 170
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 Tchem Enzyme -1.80418 63.8 91
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
E3 ubiquitin-protein ligase RNF139 RNF139 Tbio Enzyme -1.17169 16.6 133
UDP-glucose:glycoprotein glucosyltransferase 1 UGGT1 Tbio Enzyme -1.60583 43.0 80
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143