Development Level

Tbio 94 | 11,651
Tchem 18 | 1,388
Tdark 15 | 6,593
Tclin 1 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 5 | 278
decreased body weight 4 | 161
abnormal behavior 3 | 298
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
increased mean corpuscular vol... 3 | 92
abnormal coat- hair morphology 2 | 19
abnormal embryo size 2 | 220
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hypoactivity 2 | 132
increased erythrocyte cell num... 2 | 39
increased mean corpuscular hem... 2 | 96
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
increased vertical activity 2 | 24
thrombocytosis 2 | 27
abnormal cranium morphology 1 | 36
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating unsatura... 1 | 2
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 100 | 11,493
ovarian cancer 80 | 8,520
osteosarcoma 70 | 7,950
medulloblastoma, large-cell 59 | 6,241
glioblastoma 57 | 5,792
atypical teratoid / rhabdoid tumor 55 | 5,112
psoriasis 49 | 6,694
ependymoma 44 | 4,679
lung cancer 42 | 4,740
Kidney cancer 36 | 2,613
group 3 medulloblastoma 32 | 4,104
invasive ductal carcinoma 32 | 2,951
lung carcinoma 32 | 2,843
oligodendroglioma 31 | 2,850
subependymal giant cell astrocytoma 30 | 2,287
Astrocytoma, Pilocytic 29 | 3,081
Breast cancer 29 | 3,578
adult high grade glioma 29 | 3,801
Pick disease 27 | 1,894
astrocytic glioma 26 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
malignant mesothelioma 24 | 3,232
non-small cell lung cancer 23 | 2,890
primitive neuroectodermal tumor 22 | 3,035
tuberculosis 22 | 2,010
interstitial cystitis 21 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
group 4 medulloblastoma 20 | 1,855
Schizophrenia 19 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung adenocarcinoma 18 | 2,716
pancreatic cancer 18 | 2,398
Alzheimer's disease 16 | 658
Cancer 16 | 2,499
diabetes mellitus 15 | 1,728
ductal carcinoma in situ 15 | 1,745
juvenile dermatomyositis 15 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
pediatric high grade glioma 15 | 1,064
Autosomal recessive predisposition 14 | 1,442
gastric carcinoma 14 | 807
acute quadriplegic myopathy 13 | 1,158
cystic fibrosis 13 | 1,696
dermatomyositis 11 | 966
pituitary cancer 11 | 1,972
Liver cancer 10 | 604
Multiple myeloma 10 | 1,332
adrenocortical carcinoma 10 | 1,428
astrocytoma 10 | 1,146
breast carcinoma 10 | 1,638
colon cancer 10 | 1,478
primary pancreatic ductal adenocarcinoma 10 | 1,109
Bipolar Disorder 9 | 666
Down syndrome 9 | 499
Epilepsy 9 | 792
Intellectual disability 9 | 1,016
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
ulcerative colitis 9 | 1,819
Amyotrophic lateral sclerosis 8 | 451
Atopic dermatitis 8 | 952
Dull intelligence 8 | 645
Low intelligence 8 | 645
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Muscle hypotonia 8 | 571
Neurodegenerative disease 8 | 414
Poor school performance 8 | 645
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Liver Cirrhosis, Experimental 7 | 769
Mental and motor retardation 7 | 608
Parkinson's disease 7 | 392
Seizures 7 | 596
aldosterone-producing adenoma 7 | 665
cutaneous lupus erythematosus 7 | 1,057
medulloblastoma 7 | 720
mucosa-associated lymphoid tissue lymphoma 7 | 484
primary Sjogren syndrome 7 | 735
progressive supranuclear palsy 7 | 676
spina bifida 7 | 1,074
Big calvaria 6 | 147
Cardiovascular system disease 6 | 246
Dementia 6 | 175
Duchenne muscular dystrophy 6 | 601
Gaucher disease type 1 6 | 180
Increased head circumference 6 | 147
Increased size of cranium 6 | 147
Increased size of skull 6 | 147
Myocardial Ischemia 6 | 169
acute myeloid leukemia 6 | 783
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 559
Polycystic ovary syndrome 5 | 360
Rheumatoid arthritis 5 | 1,191
Short stature 5 | 531
Vascular disease 5 | 319
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
pancreatic carcinoma 5 | 562

Tissue

Digestive Tract 128 | 17,369
Endocrine System 128 | 18,159
Female tissues 128 | 17,400
Skin and soft tissues 128 | 17,230
Male tissues 127 | 17,142
Respiratory system 127 | 16,393
Urinary Tract 127 | 16,678
Blood and immune system 126 | 16,909
Liver and Pancreas 126 | 16,750
Nervous System 125 | 16,725
Cardiovascular System 121 | 15,192

Target Family

Non-IDG 91 | 12,091
Enzyme 22 | 4,145
Kinase 12 | 634
Transporter 2 | 473
Ion Channel 1 | 344

GO Process

endocytosis 128 | 128
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Equatorin EQTN Tdark Non-IDG -1.22168 17.0 17
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
Sorting nexin-9 SNX9 Tbio Non-IDG -2.00279 102.8 241
Sorting nexin-8 SNX8 Tbio Non-IDG -1.38931 25.5 152
Sorting nexin-32 SNX32 Tdark Non-IDG 0.35 0.28 89
Protein kinase C and casein kinase substrate in neurons protein 3 PACSIN3 Tbio Enzyme -0.67239 5.43 259
Sorting nexin-11 SNX11 Tdark Non-IDG -0.22185 1.79 111
Endophilin-A3 SH3GL3 Tbio Non-IDG -1.03962 9.87 97
Stabilin-2 STAB2 Tbio Non-IDG -2.81864 640.7 72