Development Level

Tbio 23 | 11,445
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
cataract 2 | 92
increased circulating HDL chol... 2 | 80
abnormal lens morphology 1 | 81
absent startle reflex 1 | 24
decreased circulating free fat... 1 | 31
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 18 | 8,520
Carcinoma 16 | 11,493
osteosarcoma 15 | 7,950
medulloblastoma, large-cell 12 | 6,241
glioblastoma 10 | 5,792
psoriasis 10 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
Pick disease 6 | 1,894
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
lung cancer 6 | 4,740
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
primitive neuroectodermal tumor 5 | 3,035
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
gastric carcinoma 4 | 807
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010
Hypomyelinating leukodystrophy 6 3 | 26
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Chronic obstructive pulmonary disease 2 | 184
Prostate cancer 2 | 175
Prostatic Neoplasms 2 | 495
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
nephrosclerosis 2 | 333
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
Acquired scoliosis 1 | 281
Amyotrophic lateral sclerosis 1 | 451
Atrophy of cerebellum 1 | 103
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Contracture 1 | 96
Contracture of joint 1 | 93
Coronary artery disease 1 | 268
Crohn Disease 1 | 45
Curvature of spine 1 | 282
Degenerative brain disorder 1 | 100
Epilepsy 1 | 792
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Gaucher disease type 1 1 | 180
Globe disease 1 | 67
Hyperandrogenism 1 | 34
Hypohidrosis 1 | 34
Hypoplasia of corpus callosum 1 | 90
Infantile onset 1 | 238
Infratentorial atrophy 1 | 103
Liver cancer 1 | 604
Major Depressive Disorder 1 | 301
Microcephaly 1 | 166
Neonatal Hypotonia 1 | 64
Neurodegenerative disease 1 | 414
Osteoporosis 1 | 363
Pathological gambling 1 | 15
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Progressive disorder 1 | 142
Seizures 1 | 596
Supratentorial atrophy 1 | 94
Unipolar Depression 1 | 250
adrenocortical adenoma 1 | 131
interleukin-7 receptor alpha deficiency 1 | 18
medulloblastoma 1 | 720
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 6 | 4,145
Kinase 1 | 634

GO Process

endocytic recycling 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ectopic P granules protein 5 homolog EPG5 Tbio Non-IDG -1.36198 23.3 33
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.47825 30.5 103
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.40524 27.4 73
Rab11 family-interacting protein 3 RAB11FIP3 Tbio Non-IDG -0.89095 6.62 68
MICAL-like protein 2 MICALL2 Tbio Non-IDG -0.91217 11.2 67
Ras-related protein Rab-35 RAB35 Tbio Enzyme -1.61645 42.9 224
DENN domain-containing protein 1A DENND1A Tbio Non-IDG -1.14835 13.7 90
EH domain-containing protein 4 EHD4 Tbio Non-IDG -1.23645 15.9 103
Tyrosine-protein phosphatase non-receptor type 23 PTPN23 Tbio Enzyme -1.41527 29.6 103