Development Level

Tbio 11 | 11,651
Tchem 5 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal vertebrae morphology 1 | 18
decreased blood urea nitrogen ... 1 | 51
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278

Disease

Cancer 12 | 2,499
Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
psoriasis 10 | 6,694
osteosarcoma 9 | 7,950
lung adenocarcinoma 8 | 2,716
lung cancer 8 | 4,740
glioblastoma 7 | 5,792
Breast Neoplasms 6 | 445
Breast cancer 6 | 3,578
Heart disease 6 | 306
Mammary Neoplasms 6 | 425
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Astrocytoma, Pilocytic 5 | 3,081
Cleft Palate 5 | 271
Congenital heart disease 5 | 93
Short stature 5 | 531
astrocytoma 5 | 1,146
atypical teratoid / rhabdoid tumor 5 | 5,112
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
Brachydactyly 4 | 156
Craniofacial Abnormalities 4 | 151
Osteoarthritis 4 | 184
Osteoporosis 4 | 363
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
Acquired scoliosis 3 | 281
Anemia 3 | 365
Ankylosis 3 | 28
Bilateral fifth finger clinodactyly 3 | 110
Broad hallux 3 | 29
Bunion 3 | 26
Congenital Heart Defects 3 | 58
Congenital deafness 3 | 185
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Cyanosis 3 | 17
Deafness 3 | 198
Failure to gain weight 3 | 365
Fibrodysplasia ossificans progressiva 3 | 17
Hallux Valgus 3 | 26
Hearing Loss, Partial 3 | 185
Hemangioma, Cavernous 3 | 20
Hemoglobin low 3 | 124
Hereditary hemorrhagic telangiectasia 3 | 13
Hypertension 3 | 396
Idiopathic pulmonary arterial hypertension 3 | 40
Liver Cirrhosis 3 | 181
Orbital separation excessive 3 | 244
Otosclerosis 3 | 15
Pediatric failure to thrive 3 | 365
Pulmonary hypertension 3 | 86
Short hallux 3 | 16
Strabismus 3 | 270
Syndactyly of fingers 3 | 48
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
hearing impairment 3 | 199
pulmonary arterial hypertension 3 | 76
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Angiodysplasia 2 | 5
Arteriovenous malformation 2 | 6
Brain Abscess 2 | 2
Cholecystitis 2 | 18
Clubbing 2 | 9
Dyspnea 2 | 76
Epistaxis 2 | 43
Hematemesis 2 | 4
Hematochezia 2 | 9
Hypertension, Portal 2 | 22
Hypotrophic malar bone 2 | 129
Iron-Refractory Iron Deficiency Anemia 2 | 15
Lymphoma 2 | 81
Malar flattening 2 | 129
Melena 2 | 2
Migraine Disorders 2 | 76
Polycythemia 2 | 25
Primary pulmonary hypertension 2 | 14
Subarachnoid Hemorrhage 2 | 7
Telangiectasis 2 | 36
Transient Cerebral Ischemia 2 | 25
non-small cell lung carcinoma 2 | 317

Tissue

Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230

Target Family

Transcription Factor 7 | 1,400
Non-IDG 5 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145

GO Process

endocardial cushion morphogene... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX20 TBX20 Tbio Transcription Factor -1.74657 63.3 109
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.41690 2313.9 1252
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Hairy/enhancer-of-split related with YRPW motif protein 1 HEY1 Tbio Transcription Factor -2.28398 163.4 335