Development Level

Tbio 10 | 10,625
Tchem 6 | 1,890

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal retina morphology 1 | 100
abnormal sleep behavior 1 | 63
decreased blood urea nitrogen ... 1 | 31

Disease

Cancer 11 | 2,346
ovarian cancer 10 | 8,492
psoriasis 10 | 6,685
osteosarcoma 9 | 7,933
lung adenocarcinoma 8 | 2,714
lung cancer 7 | 4,473
Heart disease 6 | 279
Mammary Neoplasms 6 | 410
astrocytoma 6 | 1,493
glioblastoma 6 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
malignant mesothelioma 6 | 3,163
Breast cancer 5 | 3,099
cystic fibrosis 5 | 1,670
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung carcinoma 5 | 2,844
medulloblastoma, large-cell 5 | 6,234
non-small cell lung cancer 5 | 2,798
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
Cleft palate 4 | 125
Craniofacial Abnormalities 4 | 147
Osteoarthritis 4 | 96
atypical teratoid/rhabdoid tumor 4 | 1,095
group 4 medulloblastoma 4 | 1,875
interstitial cystitis 4 | 2,299
invasive ductal carcinoma 4 | 2,950
pancreatic cancer 4 | 2,300
primitive neuroectodermal tumor 4 | 3,031
Ankylosis 3 | 25
Congenital heart disease 3 | 63
Fibrodysplasia ossificans progressiva 3 | 17
Hereditary hemorrhagic telangiectasia 3 | 14
Osteoporosis 3 | 259
Otosclerosis 3 | 13
acute quadriplegic myopathy 3 | 1,157
atypical teratoid / rhabdoid tumor 3 | 4,369
colon cancer 3 | 1,475
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
gastric carcinoma 3 | 832
non-small cell lung carcinoma 3 | 413
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Angiodysplasia 2 | 5
Arteriovenous malformation 2 | 8
Carcinoma, Pancreatic Ductal 2 | 19
Cerebrovascular disease 2 | 231
Child Development Disorders, Pervasive 2 | 55
Congenital Heart Defects 2 | 37
Craniosynostosis 2 | 47
Degenerative disc disease 2 | 28
Eye Abnormalities 2 | 15
Glaucoma 2 | 135
Hypertension 2 | 293
Juvenile polyposis syndrome 2 | 7
Lung disease 2 | 136
Myopia 2 | 99
Neoplastic Cell Transformation 2 | 81
Obesity 2 | 616
Radiculopathy 2 | 15
Stomach Neoplasms 2 | 282
Telangiectasis 2 | 20
active Crohn's disease 2 | 918
adrenocortical carcinoma 2 | 1,427
astrocytic glioma 2 | 2,241
breast carcinoma 2 | 1,614
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 2,254
nephrosclerosis 2 | 329
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
tuberculosis 2 | 1,563
urothelial carcinoma 2 | 318
46, XX Testicular Disorders of Sex Development 1 | 3
46,XY partial gonadal dysgenesis 1 | 9
46,Xx Sex Reversal 1 1 | 3
Acute stress disorder 1 | 6
Arthropathy 1 | 34
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Bone Diseases 1 | 8
Bone Diseases, Developmental 1 | 25
Congenital Abnormality 1 | 11
Congenital musculoskeletal anomalies 1 | 5
Craniometaphyseal dysplasia 1 | 5
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Hajdu-Cheney syndrome 1 | 8
Hereditary Nonpolyposis Colorectal Cancer 1 | 13
Loeys-Dietz syndrome 1 | 23
Loeys-Dietz syndrome 4 1 | 4
Macular holes 1 | 9
Neuroectodermal Tumor, Primitive 1 | 8
Ostium secundum atrial septal defect 1 | 8
Retinal detachment 1 | 33
Ureteral obstruction 1 | 6
XX males 1 | 3
bladder exstrophy 1 | 12

Tissue

Blood and immune system 16 | 17,995
Cardiovascular System 16 | 17,958
Digestive Tract 16 | 18,473
Endocrine System 16 | 18,512
Female tissues 16 | 18,647
Liver and Pancreas 16 | 18,136
Male tissues 16 | 17,969
Nervous System 16 | 18,561
Respiratory system 16 | 17,484
Skin and soft tissues 16 | 18,115
Urinary Tract 16 | 18,444

Target Family

Transcription Factor 7 | 1,400
Non-IDG 5 | 11,969
Kinase 3 | 634
Enzyme 1 | 4,146

GO Process

endocardial cushion morphogene... 16 | 16
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.94687 878.8 381
Endoglin ENG Tbio Non-IDG -3.07363 1147.6 1239
Hairy/enhancer-of-split related with YRPW motif protein 1 HEY1 Tbio Transcription Factor -2.25367 153.6 298
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.39065 2174.7 1062
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.61354 391.4 341
T-box transcription factor TBX20 TBX20 Tbio Transcription Factor -1.73587 64.8 87
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.09917 1202.5 546
Transforming growth factor beta-2 TGFB2 Tchem Non-IDG -3.13045 1015.3 342
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.31946 194.1 500
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.05076 11093.3 724