Development Level

Tbio 39 | 11,651
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal craniofacial morpholo... 1 | 33
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased blood urea nitrogen ... 1 | 51
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
long tibia 1 | 25
preweaning lethality, complete... 1 | 979
shortened QT interval 1 | 4
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 25 | 11,493
ovarian cancer 22 | 8,520
Breast cancer 17 | 3,578
glioblastoma 17 | 5,792
psoriasis 17 | 6,694
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
lung cancer 12 | 4,740
osteosarcoma 12 | 7,950
Cancer 11 | 2,499
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
malignant mesothelioma 11 | 3,232
pancreatic cancer 11 | 2,398
Craniofacial Abnormalities 10 | 151
primitive neuroectodermal tumor 10 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Astrocytoma, Pilocytic 8 | 3,081
Cleft Palate 8 | 271
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
Intellectual disability 7 | 1,016
Kidney cancer 7 | 2,613
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
oligodendroglioma 7 | 2,850
Autosomal recessive predisposition 6 | 1,442
Broad flat nasal bridge 6 | 236
Concave bridge of nose 6 | 195
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Dull intelligence 6 | 645
Low intelligence 6 | 645
Low set ears 6 | 181
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Nasal bridge wide 6 | 236
Poor school performance 6 | 645
Short stature 6 | 531
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
cutaneous lupus erythematosus 6 | 1,057
group 4 medulloblastoma 6 | 1,855
pediatric high grade glioma 6 | 1,064
ulcerative colitis 6 | 1,819
Anteverted nostril 5 | 191
Byzanthine arch palate 5 | 194
Uranostaphyloschisis 5 | 167
adrenocortical carcinoma 5 | 1,428
Congenital Camptodactyly 4 | 40
Congenital Epicanthus 4 | 177
Congenital deafness 4 | 185
Cryptorchidism 4 | 296
Deafness 4 | 198
Decreased projection of midface 4 | 105
Esophageal atresia 4 | 43
Frontal bossing 4 | 157
Hearing Loss, Partial 4 | 185
Hypoplastic mandible condyle 4 | 275
Hypotrophic midface 4 | 105
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Midface retrusion 4 | 105
Obesity 4 | 678
Orbital separation excessive 4 | 244
Polydactyly 4 | 107
Small midface 4 | 105
VACTERL association 4 | 26
gastric carcinoma 4 | 807
hearing impairment 4 | 199
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Absent auditory canals 3 | 23
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Long face 3 | 71
Mental and motor retardation 3 | 608
Posteriorly rotated ear 3 | 61
RENAL ADYSPLASIA 3 | 25
Seizures 3 | 596
Short nose 3 | 132
Skin cancer 3 | 469
Small head 3 | 374
Small nose 3 | 132
Ulnar polydactyly of fingers 3 | 47
head and neck cancer 3 | 271
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Skin and soft tissues 40 | 17,230
Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Female tissues 38 | 17,400
Male tissues 38 | 17,142
Urinary Tract 37 | 16,678
Blood and immune system 35 | 16,909
Liver and Pancreas 35 | 16,750
Respiratory system 33 | 16,393
Nervous System 30 | 16,725
Cardiovascular System 25 | 15,192

Target Family

Transcription Factor 28 | 1,400
Non-IDG 11 | 12,091
Kinase 1 | 634

GO Process

embryonic skeletal system morp... 40 | 40
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Hox-D10 HOXD10 Tbio Transcription Factor -1.78620 51.3 214
Protein fuzzy homolog FUZ Tbio Non-IDG -1.55914 36.3 72
Feline leukemia virus subgroup C receptor-related protein 1 FLVCR1 Tbio Non-IDG -1.54460 33.8 139
Polycomb group RING finger protein 2 PCGF2 Tbio Non-IDG -1.59185 43.8 189
Disks large homolog 1 DLG1 Tbio Non-IDG -2.19822 171.8 185
DNA-binding protein SATB2 SATB2 Tbio Transcription Factor -2.88608 726.3 200
Myogenic factor 5 MYF5 Tbio Transcription Factor -2.51865 298.8 320
Homeobox protein Hox-B5 HOXB5 Tbio Transcription Factor -1.83782 66.4 179
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.19296 1388.8 190
Homeobox protein Hox-D4 HOXD4 Tbio Transcription Factor -1.70582 47.6 143