Development Level

Tbio 23 | 10,625
Tchem 4 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 4 | 633
abnormal embryo size 3 | 112
embryonic lethality prior to t... 3 | 187
abnormal body wall morphology 2 | 7
cleft palate 2 | 6
preweaning lethality, incomple... 2 | 260
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal motor learning 1 | 4
abnormal nail morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal retinal vasculature m... 1 | 15
abnormal tail morphology 1 | 17
anophthalmia 1 | 20
cataract 1 | 26
craniofacial phenotype 1 | 9
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating insulin ... 1 | 75
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
hemorrhage 1 | 12
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
limb grasping 1 | 35
microphthalmia 1 | 15
prenatal lethality prior to he... 1 | 64

Disease

osteosarcoma 19 | 7,933
glioblastoma 16 | 5,572
ovarian cancer 16 | 8,491
medulloblastoma, large-cell 15 | 6,234
Cancer 13 | 2,346
invasive ductal carcinoma 13 | 2,950
interstitial cystitis 12 | 2,299
psoriasis 12 | 6,685
atypical teratoid / rhabdoid tumor 11 | 4,369
pilocytic astrocytoma 11 | 3,086
Breast cancer 10 | 3,098
non-small cell lung cancer 10 | 2,798
breast carcinoma 9 | 1,614
colon cancer 9 | 1,475
cystic fibrosis 9 | 1,670
lung cancer 8 | 4,473
malignant mesothelioma 8 | 3,163
pediatric high grade glioma 8 | 2,712
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,031
adult high grade glioma 7 | 2,148
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
oligodendroglioma 7 | 2,849
pancreatic cancer 7 | 2,300
astrocytic glioma 6 | 2,241
astrocytoma 6 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
medulloblastoma 6 | 1,524
Atopic dermatitis 5 | 944
Carcinoma 5 | 2,147
Cleft palate 5 | 125
adrenocortical carcinoma 5 | 1,427
posterior fossa group B ependymoma 5 | 1,530
primary pancreatic ductal adenocarcinoma 5 | 1,271
Acquired metabolic disease 4 | 267
Cleft Lip 4 | 91
active ulcerative colitis 4 | 477
acute quadriplegic myopathy 4 | 1,157
cutaneous lupus erythematosus 4 | 1,056
ependymoma 4 | 2,514
gastric carcinoma 4 | 832
group 3 medulloblastoma 4 | 2,254
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
juvenile dermatomyositis 4 | 1,189
lung adenocarcinoma 4 | 2,714
nasopharyngeal carcinoma 4 | 1,056
sonic hedgehog group medulloblastoma 4 | 1,482
ulcerative colitis 4 | 2,087
Multiple synostoses syndrome 3 | 8
Osteoporosis 3 | 259
Synostosis 3 | 18
aldosterone-producing adenoma 3 | 664
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
glioblastoma multiforme 3 | 347
posterior fossa group A ependymoma 3 | 1,511
primary Sjogren syndrome 3 | 788
spina bifida 3 | 1,064
Craniofacial Abnormalities 2 | 147
Duchenne muscular dystrophy 2 | 602
Esophageal atresia 2 | 25
Heart conduction disease 2 | 65
Hydrolethalus syndrome 2 | 128
Hypospadias 2 | 65
Intellectual disability 2 | 573
Joubert syndrome 2 | 62
Kidney Diseases 2 | 86
Lung Neoplasms 2 | 171
Microphthalmia 2 | 79
Multiple synostosis syndrome 2 | 3
Mycobacterium avium complex disease 2 | 11
Obesity 2 | 616
Otosclerosis 2 | 13
Polycystic Ovary Syndrome 2 | 334
Polydactyly 2 | 93
Proximal symphalangism 2 | 6
Spontaneous abortion 2 | 108
Symphalangism-brachydactyly syndrome 2 | 3
Syndactyly 2 | 56
X-linked cerebral adrenoleukodystrophy 2 | 115
acute myeloid leukemia 2 | 785
adrenocortical adenoma 2 | 134
dermatomyositis 2 | 966
fibroadenoma 2 | 557
head and neck cancer 2 | 270
inflammatory breast cancer 2 | 404
lung carcinoma 2 | 2,844
ovarian neoplasm 2 | 97
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
sarcoidosis 2 | 368
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
tuberculosis and treatment for 3 months 2 | 327
urothelial carcinoma 2 | 318
Bone Diseases, Developmental 1 | 25
Congenital ocular coloboma (disorder) 1 | 12
Jaw Abnormalities 1 | 5
Lower Extremity Deformities, Congenital 1 | 2

Tissue

Female tissues 30 | 18,646
Blood and immune system 29 | 17,994
Cardiovascular System 29 | 17,957
Digestive Tract 29 | 18,472
Endocrine System 29 | 18,511
Liver and Pancreas 29 | 18,135
Male tissues 29 | 17,968
Nervous System 29 | 18,560
Skin and soft tissues 29 | 18,114
Urinary Tract 29 | 18,443
Respiratory system 27 | 17,483

Target Family

Transcription Factor 14 | 1,400
Non-IDG 10 | 11,969
Enzyme 3 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

GO Process

embryonic skeletal system deve... 30 | 30
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.29669 19.6 50
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.94271 807.7 451
Pre-B-cell leukemia transcription factor 1 PBX1 Tbio Transcription Factor -2.29016 188.5 219
Transcription factor Sp3 SP3 Tbio Transcription Factor -2.48548 281.9 319
Deformed epidermal autoregulatory factor 1 homolog DEAF1 Tbio Transcription Factor -1.67990 49.3 219
Paired box protein Pax-7 PAX7 Tbio Transcription Factor -2.67125 430.7 354
Transmembrane anterior posterior transformation protein 1 homolog TAPT1 Tdark Non-IDG -0.44214 3.02 55
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.85392 697.2 118
Protein Wnt-11 WNT11 Tbio Non-IDG -2.06036 113.7 91
Homeobox protein DLX-1 DLX1 Tbio Transcription Factor -1.62612 40.2 209