Development Level

Tbio 21 | 11,445
Tchem 4 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal body wall morphology 2 | 9
cleft palate 2 | 8
enlarged heart 2 | 210
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal vasculature m... 1 | 27
abnormal tail morphology 1 | 25
anophthalmia 1 | 33
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 18 | 11,493
osteosarcoma 18 | 7,950
glioblastoma 16 | 5,792
Cancer 15 | 2,499
medulloblastoma, large-cell 15 | 6,241
ovarian cancer 14 | 8,520
atypical teratoid / rhabdoid tumor 12 | 5,112
invasive ductal carcinoma 12 | 2,951
Astrocytoma, Pilocytic 11 | 3,081
interstitial cystitis 11 | 2,312
psoriasis 11 | 6,694
adult high grade glioma 10 | 3,801
ependymoma 10 | 4,679
non-small cell lung cancer 10 | 2,890
Breast cancer 9 | 3,578
astrocytic glioma 9 | 2,597
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
pancreatic cancer 8 | 2,398
primitive neuroectodermal tumor 8 | 3,035
ductal carcinoma in situ 7 | 1,745
malignant mesothelioma 7 | 3,232
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
Autosomal recessive predisposition 6 | 1,442
Cleft Lip 6 | 141
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Acquired metabolic disease 5 | 336
Cleft Palate 5 | 271
active ulcerative colitis 5 | 764
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Osteoporosis 4 | 363
Poor school performance 4 | 645
Short stature 4 | 531
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
Abnormally small eyeball 3 | 97
Congenital clinodactyly 3 | 57
Curvature of digit 3 | 57
Decreased projection of midface 3 | 105
Decreased size of eyeball 3 | 97
Hypoplastic mandible condyle 3 | 275
Hypotrophic malar bone 3 | 129
Hypotrophic midface 3 | 105
Liver cancer 3 | 604
Malar flattening 3 | 129
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Microphthalmos 3 | 100
Midface retrusion 3 | 105
Multiple synostoses syndrome 3 | 9
Orbital separation excessive 3 | 244
Ovarian Neoplasms 3 | 102
Pectus excavatum 3 | 100
Radially deviated fingers 3 | 38
Small midface 3 | 105
Syndactyly 3 | 88
Synostosis 3 | 15
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
spina bifida 3 | 1,074
Abortion, Spontaneous 2 | 109
Attention deficit hyperactivity disorder 2 | 278
Epilepsy 2 | 792
Hypertension 2 | 396
Polycystic ovary syndrome 2 | 360
Spontaneous abortion 2 | 113
Strabismus 2 | 270
Syndactyly of the toes 2 | 45
Umbilical hernia 2 | 93
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
fibroadenoma 2 | 559
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Skin and soft tissues 28 | 17,230
Male tissues 27 | 17,142
Blood and immune system 26 | 16,909
Female tissues 26 | 17,400
Urinary Tract 26 | 16,678
Nervous System 25 | 16,725
Liver and Pancreas 24 | 16,750
Respiratory system 24 | 16,393
Cardiovascular System 21 | 15,192

Target Family

Transcription Factor 13 | 1,400
Non-IDG 10 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

embryonic skeletal system deve... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MBT domain-containing protein 1 MBTD1 Tdark Epigenetic -0.59314 4.06 83
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Doublesex- and mab-3-related transcription factor 2 DMRT2 Tdark Transcription Factor -1.38317 20.7 50
Homeobox protein Hox-C5 HOXC5 Tbio Transcription Factor -1.08912 11.9 114
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Homeobox protein Hox-D1 HOXD1 Tbio Transcription Factor -1.21276 16.6 131
Homeobox protein Hox-C6 HOXC6 Tbio Transcription Factor -1.83911 68.9 201
Sickle tail protein homolog KIAA1217 Tbio Non-IDG -2.21538 156.5 15