Development Level

Tbio 18 | 11,651
Tchem 2 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26

Disease

Carcinoma 17 | 11,493
ovarian cancer 16 | 8,520
osteosarcoma 15 | 7,950
group 3 medulloblastoma 11 | 4,104
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
psoriasis 9 | 6,694
Cancer 8 | 2,499
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
medulloblastoma, large-cell 7 | 6,241
glioblastoma 6 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Autosomal recessive predisposition 5 | 1,442
Short stature 5 | 531
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Abnormally small eyeball 4 | 97
Cataract 4 | 297
Cockayne syndrome 4 | 60
Cognitive delay 4 | 608
Craniofacial Abnormalities 4 | 151
Cryptorchidism 4 | 296
Decreased size of eyeball 4 | 97
Dull intelligence 4 | 645
Epilepsy 4 | 792
Global developmental delay 4 | 608
Hydrocephalus 4 | 152
Intellectual disability 4 | 1,016
Lens Opacities 4 | 231
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Microphthalmos 4 | 100
Photosensitive trichothiodystrophy 4 | 30
Poor school performance 4 | 645
Seizures 4 | 596
Strabismus 4 | 270
Xeroderma pigmentosum 4 | 43
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
non primary Sjogren syndrome sicca 4 | 891
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Brachydactyly 3 | 156
Broad flat nasal bridge 3 | 236
Broad forehead 3 | 59
Congenital anomaly of face 3 | 56
Congenital deafness 3 | 185
Deafness 3 | 198
Dilated ventricles (finding) 3 | 121
Electroencephalogram abnormal 3 | 101
Endometrial cancer 3 | 311
Failure to gain weight 3 | 365
Feeding difficulties in infancy 3 | 175
Fetal Growth Retardation 3 | 189
Flexion contracture of proximal interphalangeal joint 3 | 75
Hearing Loss, Partial 3 | 185
Highly variable severity 3 | 157
Hypogonadism 3 | 173
Hypoplastic mandible condyle 3 | 275
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Liver cancer 3 | 604
Low Vision 3 | 174
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Nasal bridge wide 3 | 236
Optic Atrophy 3 | 242
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Retinal Diseases 3 | 55
Schizophrenia 3 | 1,160
Sensorineural Hearing Loss (disorder) 3 | 284
Short neck 3 | 140
Small head 3 | 374
Stomach Neoplasms 3 | 300
Variable expressivity 3 | 157
Vertical Talus 3 | 25
Visual Impairment 3 | 174
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
hearing impairment 3 | 199
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 8 | 1,400
Enzyme 4 | 4,145
Kinase 2 | 634

GO Process

embryonic organ development 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
Pre-mRNA-splicing factor SYF2 SYF2 Tbio Non-IDG -1.04825 13.2 124
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.71108 45.2 164
Partner and localizer of BRCA2 PALB2 Tbio Non-IDG -2.16005 165.4 154
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.99412 96.8 313
DNA polymerase epsilon catalytic subunit A POLE Tclin Enzyme -2.22644 169.3 112
WD repeat-containing protein 48 WDR48 Tbio Non-IDG -1.30587 20.1 74
Transcriptional enhancer factor TEF-3 TEAD4 Tbio Transcription Factor -1.64976 46.2 191
Transcriptional enhancer factor TEF-4 TEAD2 Tbio Transcription Factor -1.43970 26.0 199