Development Level

Tbio 4 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
long tibia 1 | 25

Disease

Brachydactyly 3 | 156
Cryptorchidism 3 | 296
osteosarcoma 3 | 7,950
Abnormal nasal morphology 2 | 16
Atrial heart septal defect 2 | 18
Autosomal recessive predisposition 2 | 1,442
Bilateral fifth finger clinodactyly 2 | 110
Broad forehead 2 | 59
Carcinoma 2 | 11,493
Congenital heart disease 2 | 93
Craniosynostosis 2 | 74
Curvature of little finger 2 | 110
Exophthalmos 2 | 112
Fetal Growth Retardation 2 | 189
Heart Septal Defects, Ventricular 2 | 6
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Kidney cancer 2 | 2,613
Long narrow head 2 | 75
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Ostium secundum atrial septal defect 2 | 9
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Right atrial isomerism 2 | 29
Tetralogy of Fallot 2 | 63
Thin lips 2 | 49
Turridolichocephaly 2 | 75
Underdeveloped brows 2 | 38
Underdeveloped supraorbital ridges 2 | 38
Ventricular Septal Defects 2 | 119
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
ovarian cancer 2 | 8,520
ventricular septal defect 2 | 20
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
ATRIAL SEPTAL DEFECT 8 1 | 1
Accessory nipple 1 | 11
Acrocephalopolysyndactyly Type II 1 | 2
Acrocephalopolysyndactyly type 2 1 | 2
Acrocephaly 1 | 12
Acrofacial dysostosis 1 | 8
Asphyxiating thoracic dystrophy 1 | 44
Atrial Septal Defect Sinus Venosus 1 | 1
Atrioventricular block 1 | 35
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Beemer-Langer syndrome 1 | 1
Bowed and upward slanting eyebrows 1 | 41
Broad hallux 1 | 29
Broad thumbs 1 | 28
Cardiomegaly 1 | 116
Chronic dacryocystitis 1 | 2
Ciliary Motility Disorders 1 | 38
Ciliopathy 1 | 71
Cloverleaf cranium shape 1 | 6
Cloverleaf skull 1 | 7
Congenital Camptodactyly 1 | 40
Congenital hypothyroidism 1 | 26
Congenital pectus carinatum 1 | 52
Conotruncal Heart Malformations 1 | 10
Corneal abnormalities 1 | 6
Cornela disease 1 | 6
Cutaneous finger syndactyly 1 | 11
Decreased projection of midface 1 | 105
Discordant ventriculoarterial connection 1 | 17
Ebstein anomaly 1 | 16
Ellis-Van Creveld syndrome 1 | 19
Familial hemophagocytic lymphohistiocytosis 1 1 | 11
Familial hemophagocytic lymphohistiocytosis 2 1 | 15
Holt-Oram syndrome 1 | 12
Hordeolum 1 | 5
Hypoplasia of nipple 1 | 16
Hypoplastic Left Heart Syndrome 1 | 14
Hypotrophic midface 1 | 105
Knee joint valgus deformity 1 | 56
Midface retrusion 1 | 105
Narrow palate 1 | 20
Neoplasms 1 | 63
POLYDACTYLY, POSTAXIAL 1 | 13
Perimembranous ventricular septal defect 1 | 3
Preaxial Hallucal Polydactyly 1 | 3
Preaxial foot polydactyly 1 | 3
Progressive mental retardation 1 | 37
Radial polydactyly 1 | 8
Sensenbrenner syndrome 1 | 17
Small midface 1 | 105
Sparse eyebrow 1 | 42
Syndactyly of fingers 1 | 48
Thick, flared eyebrows 1 | 41
Tricuspid atresia 1 | 7
Ventricular septal defect 2 1 | 1
Wide spaced nipples 1 | 46
heart septal defect 1 | 1

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Female tissues 4 | 17,400
Urinary Tract 4 | 16,678
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230

Target Family

Non-IDG 3 | 12,091
Transcription Factor 1 | 1,400

GO Process

embryonic heart tube left-righ... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Multiple epidermal growth factor-like domains protein 8 MEGF8 Tbio Non-IDG -0.21967 1.88 58
Intraflagellar transport protein 122 homolog IFT122 Tbio Non-IDG -1.52417 33.7 53
Cbp/p300-interacting transactivator 2 CITED2 Tbio Non-IDG -2.07760 134.8 167
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385