Development Level

Tbio 41 | 10,625
Tchem 8 | 1,890
Tdark 5 | 7,003
Tclin 2 | 602

IMPC Term

decreased body weight 3 | 174
decreased lean body mass 3 | 195
preweaning lethality, complete... 3 | 633
abnormal bone mineralization 2 | 55
abnormal startle reflex 2 | 14
impaired glucose tolerance 2 | 52
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal nail morphology 1 | 7
abnormal response to tactile s... 1 | 16
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased fasted circulating g... 1 | 49
decreased prepulse inhibition 1 | 52
embryonic lethality prior to t... 1 | 187
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating aspartat... 1 | 17
increased total body fat amoun... 1 | 57
kinked tail 1 | 3
limb grasping 1 | 35

Disease

osteosarcoma 34 | 7,933
ovarian cancer 30 | 8,484
Cancer 24 | 2,346
medulloblastoma, large-cell 23 | 6,234
psoriasis 23 | 6,685
Polydactyly 21 | 93
lung cancer 18 | 4,466
Breast cancer 15 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
atypical teratoid / rhabdoid tumor 13 | 4,369
glioblastoma 13 | 5,572
Carcinoma 12 | 2,147
invasive ductal carcinoma 12 | 2,950
pediatric high grade glioma 12 | 2,712
ductal carcinoma in situ 11 | 1,745
interstitial cystitis 11 | 2,299
non-small cell lung cancer 11 | 2,798
primitive neuroectodermal tumor 11 | 3,031
malignant mesothelioma 10 | 3,162
pancreatic cancer 10 | 2,300
posterior fossa group B ependymoma 10 | 1,530
sonic hedgehog group medulloblastoma 10 | 1,482
subependymal giant cell astrocytoma 10 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
pituitary cancer 9 | 1,972
atypical teratoid/rhabdoid tumor 8 | 1,095
ependymoma 8 | 2,514
group 4 medulloblastoma 8 | 1,875
ulcerative colitis 8 | 2,087
Intellectual disability 7 | 573
Syndactyly 7 | 56
cystic fibrosis 7 | 1,665
lung carcinoma 7 | 2,844
pilocytic astrocytoma 7 | 3,086
Atopic dermatitis 6 | 944
Brachydactyly 6 | 52
Cleft palate 6 | 125
Craniofacial Abnormalities 6 | 147
Synostosis 6 | 18
acute quadriplegic myopathy 6 | 1,157
adrenocortical carcinoma 6 | 1,427
breast carcinoma 6 | 1,614
cutaneous lupus erythematosus 6 | 1,056
lung adenocarcinoma 6 | 2,713
Adenoma 5 | 165
Endometriosis 5 | 535
Joubert syndrome 5 | 61
Limb Deformities, Congenital 5 | 16
Meckel syndrome 5 | 48
Obesity 5 | 616
astrocytoma 5 | 1,493
diabetes mellitus 5 | 1,663
group 3 medulloblastoma 5 | 2,254
oligodendroglioma 5 | 2,849
primary pancreatic ductal adenocarcinoma 5 | 1,271
Alzheimer's disease 4 | 644
Ciliopathy 4 | 57
Clubfoot 4 | 35
Colorectal Neoplasms 4 | 217
Female Urogenital Diseases 4 | 18
Holoprosencephaly 4 | 52
Mammary Neoplasms 4 | 410
Melanoma 4 | 261
Orofaciodigital syndrome 4 | 19
Osteoporosis 4 | 257
Pick disease 4 | 1,893
Prostatic Neoplasms 4 | 471
Rheumatoid Arthritis 4 | 1,160
Stomach Neoplasms 4 | 282
VACTERL association 4 | 23
adult high grade glioma 4 | 2,148
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,475
gastric carcinoma 4 | 832
medulloblastoma 4 | 1,524
nasopharyngeal carcinoma 4 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
posterior fossa group A ependymoma 4 | 1,511
tuberculosis and treatment for 3 months 4 | 327
Cleft Lip 3 | 91
Congenital Heart Defects 3 | 37
Craniosynostosis 3 | 47
Down syndrome 3 | 548
Hydrolethalus syndrome 3 | 128
Hypertension 3 | 287
Imperforate anus 3 | 14
Lung Neoplasms 3 | 171
Multiple myeloma 3 | 1,327
Neoplasm Invasiveness 3 | 127
Nephronophthisis 3 | 74
Osteoarthritis 3 | 96
active ulcerative colitis 3 | 477
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
inflammatory breast cancer 3 | 404
interstitial lung disease 3 | 291
juvenile dermatomyositis 3 | 1,189
spina bifida 3 | 1,064
tuberculosis 3 | 1,557

Tissue

Digestive Tract 56 | 18,473
Endocrine System 56 | 18,512
Female tissues 56 | 18,647
Male tissues 56 | 17,969
Nervous System 56 | 18,561
Urinary Tract 56 | 18,444
Cardiovascular System 55 | 17,958
Liver and Pancreas 55 | 18,136
Skin and soft tissues 55 | 18,115
Blood and immune system 54 | 17,995
Respiratory system 52 | 17,484

Target Family

Non-IDG 28 | 11,971
Transcription Factor 19 | 1,400
Enzyme 3 | 4,146
Epigenetic 3 | 242
Kinase 3 | 634

GO Process

embryonic digit morphogenesis 56 | 56
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase kinase kinase MLT MAP3K20 Tchem Kinase -1.14470 13.6 205
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.16723 1539.5 438
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.51321 325.2 174
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.06756 1202.0 278
Homeobox protein aristaless-like 4 ALX4 Tbio Transcription Factor -1.72143 58.9 149
Low-density lipoprotein receptor-related protein 4 LRP4 Tbio Non-IDG -1.98324 105.2 178
Heart- and neural crest derivatives-expressed protein 2 HAND2 Tbio Transcription Factor -2.96432 878.0 189
Protein inturned INTU Tbio Non-IDG -1.65090 47.8 50
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.29586 19.6 50