Development Level

Tbio 44 | 11,651
Tchem 8 | 1,388
Tdark 3 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
increased total body fat amoun... 4 | 134
decreased body weight 3 | 161
decreased lean body mass 3 | 135
increased startle reflex 3 | 112
abnormal bone mineralization 2 | 38
abnormal startle reflex 2 | 15
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
mammalian phenotype 2 | 17
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal nail morphology 1 | 8
abnormal response to tactile s... 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tail movements 1 | 12
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
kinked tail 1 | 2
limb grasping 1 | 41
long tibia 1 | 25
male infertility 1 | 123

Disease

Carcinoma 41 | 11,493
osteosarcoma 36 | 7,950
ovarian cancer 32 | 8,520
Cancer 25 | 2,499
Polydactyly 24 | 107
medulloblastoma, large-cell 24 | 6,241
psoriasis 23 | 6,694
ependymoma 21 | 4,679
Breast cancer 20 | 3,578
Short stature 19 | 531
atypical teratoid / rhabdoid tumor 19 | 5,112
lung cancer 19 | 4,740
Intellectual disability 16 | 1,016
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Small head 14 | 374
glioblastoma 14 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Autosomal recessive predisposition 13 | 1,442
Cryptorchidism 13 | 296
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Kidney cancer 12 | 2,613
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
invasive ductal carcinoma 12 | 2,951
pancreatic cancer 12 | 2,398
Brachydactyly 11 | 156
Cleft Palate 11 | 271
Congenital hypoplasia of penis 11 | 176
Hypoplastic mandible condyle 11 | 275
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
Orbital separation excessive 11 | 244
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
Syndactyly 10 | 88
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Patent ductus arteriosus 9 | 90
Strabismus 9 | 270
pediatric high grade glioma 9 | 1,064
pituitary cancer 9 | 1,972
Abnormally small eyeball 8 | 97
Astrocytoma, Pilocytic 8 | 3,081
Bilateral fifth finger clinodactyly 8 | 110
Broad flat nasal bridge 8 | 236
Congenital deafness 8 | 185
Curvature of little finger 8 | 110
Deafness 8 | 198
Decreased size of eyeball 8 | 97
Frontal bossing 8 | 157
Gastrointestinal Stromal Tumors 8 | 48
Hearing Loss, Partial 8 | 185
Microphthalmos 8 | 100
Nasal bridge wide 8 | 236
Ulnar polydactyly of fingers 8 | 47
Ventricular Septal Defects 8 | 119
adult high grade glioma 8 | 3,801
hearing impairment 8 | 199
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
ulcerative colitis 8 | 1,819
Cataract 7 | 297
Ciliopathy 7 | 71
Epilepsy 7 | 792
Fetal Growth Retardation 7 | 189
Hypotrophic malar bone 7 | 129
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Joubert syndrome 7 | 66
Lens Opacities 7 | 231
Malar flattening 7 | 129
Muscle hypotonia 7 | 571
Nephronophthisis 7 | 80
Seizures 7 | 596
Syndactyly of the toes 7 | 45
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
lung carcinoma 7 | 2,843
tuberculosis 7 | 2,010
Anteverted nostril 6 | 191
Atopic dermatitis 6 | 952
Congenital Epicanthus 6 | 177
Congenital clinodactyly 6 | 57
Craniosynostosis 6 | 74
Curvature of digit 6 | 57
Curvature of spine 6 | 282
Low set ears 6 | 181
Optic Atrophy 6 | 242
Pectus excavatum 6 | 100
Posteriorly rotated ear 6 | 61
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
lung adenocarcinoma 6 | 2,716

Tissue

Digestive Tract 56 | 17,369
Female tissues 56 | 17,400
Male tissues 56 | 17,142
Endocrine System 55 | 18,159
Skin and soft tissues 55 | 17,230
Urinary Tract 54 | 16,678
Liver and Pancreas 52 | 16,750
Nervous System 51 | 16,725
Blood and immune system 50 | 16,909
Respiratory system 50 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 29 | 12,091
Transcription Factor 19 | 1,400
Enzyme 3 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634

GO Process

embryonic digit morphogenesis 57 | 57
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Endoplasmic reticulum junction formation protein lunapark LNPK Tbio Non-IDG -1.07127 11.1 9
Inositol monophosphatase 3 IMPAD1 Tdark Enzyme -0.78606 4.97 79
Protein inturned INTU Tbio Non-IDG -1.76006 53.9 56
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.88065 80.4 419
Heart- and neural crest derivatives-expressed protein 2 HAND2 Tbio Transcription Factor -2.99854 926.7 220
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
Intraflagellar transport protein 122 homolog IFT122 Tbio Non-IDG -1.52417 33.7 53